The footprint of genome architecture in the largest genome expansion in RNA viruses.

The small size of RNA virus genomes (2-to-32 kb) has been attributed to high mutation rates during replication, which is thought to lack proof-reading. This paradigm is being revisited owing to the discovery of a 3'-to-5' exoribonuclease (ExoN) in nidoviruses, a monophyletic group of posit...

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Auteurs principaux: Chris Lauber, Jelle J Goeman, Maria del Carmen Parquet, Phan Thi Nga, Eric J Snijder, Kouichi Morita, Alexander E Gorbalenya
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/ffe37aa6492648b288f00d6c33ddf777
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