Autonomic dysfunction in chronic liver disease

James Frith, Julia L NewtonNIHR Biomedical Research Centre in Ageing, Institute for Ageing and Health, Newcastle University, Newcastle, UKAbstract: It is becoming increasingly clear that quality of life (QOL) is impaired in those with chronic liver disease (CLD). One of the most important contributo...

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Autores principales:	Frith J, Newton JL
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/ffeba19974414435af7c17ccfbdae1ab
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spelling	oai:doaj.org-article:ffeba19974414435af7c17ccfbdae1ab2021-12-02T01:29:20ZAutonomic dysfunction in chronic liver disease1179-1535https://doaj.org/article/ffeba19974414435af7c17ccfbdae1ab2011-08-01T00:00:00Zhttp://www.dovepress.com/autonomic-dysfunction-in-chronic-liver-disease-a8128https://doaj.org/toc/1179-1535James Frith, Julia L NewtonNIHR Biomedical Research Centre in Ageing, Institute for Ageing and Health, Newcastle University, Newcastle, UKAbstract: It is becoming increasingly clear that quality of life (QOL) is impaired in those with chronic liver disease (CLD). One of the most important contributors to impaired QOL is the symptomatic burden which can range from slight to debilitating. Autonomic dysfunction accounts for a significant proportion of these symptoms, which can be common, non-specific and challenging to treat. Investigating the autonomic nervous system can be straight forward and can assist the clinician to diagnose and treat specific symptoms. Evidence-based treatment options for autonomic symptoms, specifically in CLD, can be lacking and must be extrapolated from other studies and expert opinion. For those with severely impaired quality of life, liver transplantation may offer an improvement; however, more research is needed to confirm this.Keywords: quality of life, treatment, fatigue, angiotensin IIFrith JNewton JLDove Medical PressarticleDiseases of the digestive system. GastroenterologyRC799-869ENHepatic Medicine: Evidence and Research, Vol 2011, Iss default, Pp 81-87 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	Diseases of the digestive system. Gastroenterology RC799-869 Frith J Newton JL Autonomic dysfunction in chronic liver disease
description	James Frith, Julia L NewtonNIHR Biomedical Research Centre in Ageing, Institute for Ageing and Health, Newcastle University, Newcastle, UKAbstract: It is becoming increasingly clear that quality of life (QOL) is impaired in those with chronic liver disease (CLD). One of the most important contributors to impaired QOL is the symptomatic burden which can range from slight to debilitating. Autonomic dysfunction accounts for a significant proportion of these symptoms, which can be common, non-specific and challenging to treat. Investigating the autonomic nervous system can be straight forward and can assist the clinician to diagnose and treat specific symptoms. Evidence-based treatment options for autonomic symptoms, specifically in CLD, can be lacking and must be extrapolated from other studies and expert opinion. For those with severely impaired quality of life, liver transplantation may offer an improvement; however, more research is needed to confirm this.Keywords: quality of life, treatment, fatigue, angiotensin II
format	article
author	Frith J Newton JL
author_facet	Frith J Newton JL
author_sort	Frith J
title	Autonomic dysfunction in chronic liver disease
title_short	Autonomic dysfunction in chronic liver disease
title_full	Autonomic dysfunction in chronic liver disease
title_fullStr	Autonomic dysfunction in chronic liver disease
title_full_unstemmed	Autonomic dysfunction in chronic liver disease
title_sort	autonomic dysfunction in chronic liver disease
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/ffeba19974414435af7c17ccfbdae1ab
work_keys_str_mv	AT frithj autonomicdysfunctioninchronicliverdisease AT newtonjl autonomicdysfunctioninchronicliverdisease
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Autonomic dysfunction in chronic liver disease

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