Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage

Abstract Background Being the native inhabitants of the Neolithic Fertile Crescent, Kurds were included in several maternal lineage studies concerning the Eurasian population. However, no study was performed on the Kurdish population of Sulaymaniyah city (latitude 33.314690 and longitude 44.376759)....

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Autores principales:	Han Nihad Mohammed Fadhl, Shad Arif Mohammed, Farhad M. Abdulkarim
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Whole mitochondrial DNA Haplogroup West Eurasia Kurds Sulaymaniyah city Region of Kurdistan Law in general. Comparative and uniform law. Jurisprudence K1-7720 Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/ffeff6434cbd4fc4a1c0f5ec10f512a6
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spelling	oai:doaj.org-article:ffeff6434cbd4fc4a1c0f5ec10f512a62021-11-07T12:18:00ZMitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage10.1186/s41935-021-00246-22090-5939https://doaj.org/article/ffeff6434cbd4fc4a1c0f5ec10f512a62021-11-01T00:00:00Zhttps://doi.org/10.1186/s41935-021-00246-2https://doaj.org/toc/2090-5939Abstract Background Being the native inhabitants of the Neolithic Fertile Crescent, Kurds were included in several maternal lineage studies concerning the Eurasian population. However, no study was performed on the Kurdish population of Sulaymaniyah city (latitude 33.314690 and longitude 44.376759). This study was carried out on a sample of Sorani Kurds living in Sulaymaniyah for the identification of population-related single nucleotide polymorphisms (SNPs) and modes of maternal lineage. Results In this study, 36 randomly selected healthy unrelated Kurdish subjects were enrolled. Whole mitochondrial DNA sequencing was performed. HaploGrep 2.0 and neutrality test (Tajima’s D) were employed for haplogroup identification and historical demography determination. When the outcomes were compared with previous studies in Kurds and the neighbouring nations, the identified haplogroups in the sample of study were members of the Western Eurasian haplogroups with a predominance of haplogroup H. Conclusions The whole mitochondrial DNA sequence is superior to the traditional analysis of the non-coding (control) region. Our study indicates a stronger relation of the studied group to the European lineage than to their neighbouring nations.Han Nihad Mohammed FadhlShad Arif MohammedFarhad M. AbdulkarimSpringerOpenarticleWhole mitochondrial DNAHaplogroupWest EurasiaKurdsSulaymaniyah cityRegion of KurdistanLaw in general. Comparative and uniform law. JurisprudenceK1-7720Medicine (General)R5-920ENEgyptian Journal of Forensic Sciences, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Whole mitochondrial DNA Haplogroup West Eurasia Kurds Sulaymaniyah city Region of Kurdistan Law in general. Comparative and uniform law. Jurisprudence K1-7720 Medicine (General) R5-920
spellingShingle	Whole mitochondrial DNA Haplogroup West Eurasia Kurds Sulaymaniyah city Region of Kurdistan Law in general. Comparative and uniform law. Jurisprudence K1-7720 Medicine (General) R5-920 Han Nihad Mohammed Fadhl Shad Arif Mohammed Farhad M. Abdulkarim Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage
description	Abstract Background Being the native inhabitants of the Neolithic Fertile Crescent, Kurds were included in several maternal lineage studies concerning the Eurasian population. However, no study was performed on the Kurdish population of Sulaymaniyah city (latitude 33.314690 and longitude 44.376759). This study was carried out on a sample of Sorani Kurds living in Sulaymaniyah for the identification of population-related single nucleotide polymorphisms (SNPs) and modes of maternal lineage. Results In this study, 36 randomly selected healthy unrelated Kurdish subjects were enrolled. Whole mitochondrial DNA sequencing was performed. HaploGrep 2.0 and neutrality test (Tajima’s D) were employed for haplogroup identification and historical demography determination. When the outcomes were compared with previous studies in Kurds and the neighbouring nations, the identified haplogroups in the sample of study were members of the Western Eurasian haplogroups with a predominance of haplogroup H. Conclusions The whole mitochondrial DNA sequence is superior to the traditional analysis of the non-coding (control) region. Our study indicates a stronger relation of the studied group to the European lineage than to their neighbouring nations.
format	article
author	Han Nihad Mohammed Fadhl Shad Arif Mohammed Farhad M. Abdulkarim
author_facet	Han Nihad Mohammed Fadhl Shad Arif Mohammed Farhad M. Abdulkarim
author_sort	Han Nihad Mohammed Fadhl
title	Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage
title_short	Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage
title_full	Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage
title_fullStr	Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage
title_full_unstemmed	Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage
title_sort	mitochondrial dna haplogroup study: residents of sulaymaniyah city in the iraqi kurdistan region may be genetically closer to european lineage
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/ffeff6434cbd4fc4a1c0f5ec10f512a6
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Mitochondrial DNA haplogroup study: residents of Sulaymaniyah city in the Iraqi Kurdistan Region may be genetically closer to European lineage

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