Designed and biologically active protein lattices
Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retenti...
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Nature Portfolio
2021
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oai:doaj.org-article:fff27e4143024037b51fe7d8436773cc2021-12-02T17:23:15ZDesigned and biologically active protein lattices10.1038/s41467-021-23966-42041-1723https://doaj.org/article/fff27e4143024037b51fe7d8436773cc2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23966-4https://doaj.org/toc/2041-1723Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retention of protein function.Shih-Ting WangBrian MinevichJianfang LiuHonghu ZhangDmytro NykypanchukJames ByrnesWu LiuLev BershadskyQun LiuTong WangGang RenOleg GangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
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Science Q Shih-Ting Wang Brian Minevich Jianfang Liu Honghu Zhang Dmytro Nykypanchuk James Byrnes Wu Liu Lev Bershadsky Qun Liu Tong Wang Gang Ren Oleg Gang Designed and biologically active protein lattices |
description |
Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retention of protein function. |
format |
article |
author |
Shih-Ting Wang Brian Minevich Jianfang Liu Honghu Zhang Dmytro Nykypanchuk James Byrnes Wu Liu Lev Bershadsky Qun Liu Tong Wang Gang Ren Oleg Gang |
author_facet |
Shih-Ting Wang Brian Minevich Jianfang Liu Honghu Zhang Dmytro Nykypanchuk James Byrnes Wu Liu Lev Bershadsky Qun Liu Tong Wang Gang Ren Oleg Gang |
author_sort |
Shih-Ting Wang |
title |
Designed and biologically active protein lattices |
title_short |
Designed and biologically active protein lattices |
title_full |
Designed and biologically active protein lattices |
title_fullStr |
Designed and biologically active protein lattices |
title_full_unstemmed |
Designed and biologically active protein lattices |
title_sort |
designed and biologically active protein lattices |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/fff27e4143024037b51fe7d8436773cc |
work_keys_str_mv |
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1718381005038944256 |