Designed and biologically active protein lattices

Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retenti...

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Autores principales: Shih-Ting Wang, Brian Minevich, Jianfang Liu, Honghu Zhang, Dmytro Nykypanchuk, James Byrnes, Wu Liu, Lev Bershadsky, Qun Liu, Tong Wang, Gang Ren, Oleg Gang
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fff27e4143024037b51fe7d8436773cc
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spelling oai:doaj.org-article:fff27e4143024037b51fe7d8436773cc2021-12-02T17:23:15ZDesigned and biologically active protein lattices10.1038/s41467-021-23966-42041-1723https://doaj.org/article/fff27e4143024037b51fe7d8436773cc2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23966-4https://doaj.org/toc/2041-1723Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retention of protein function.Shih-Ting WangBrian MinevichJianfang LiuHonghu ZhangDmytro NykypanchukJames ByrnesWu LiuLev BershadskyQun LiuTong WangGang RenOleg GangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shih-Ting Wang
Brian Minevich
Jianfang Liu
Honghu Zhang
Dmytro Nykypanchuk
James Byrnes
Wu Liu
Lev Bershadsky
Qun Liu
Tong Wang
Gang Ren
Oleg Gang
Designed and biologically active protein lattices
description Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retention of protein function.
format article
author Shih-Ting Wang
Brian Minevich
Jianfang Liu
Honghu Zhang
Dmytro Nykypanchuk
James Byrnes
Wu Liu
Lev Bershadsky
Qun Liu
Tong Wang
Gang Ren
Oleg Gang
author_facet Shih-Ting Wang
Brian Minevich
Jianfang Liu
Honghu Zhang
Dmytro Nykypanchuk
James Byrnes
Wu Liu
Lev Bershadsky
Qun Liu
Tong Wang
Gang Ren
Oleg Gang
author_sort Shih-Ting Wang
title Designed and biologically active protein lattices
title_short Designed and biologically active protein lattices
title_full Designed and biologically active protein lattices
title_fullStr Designed and biologically active protein lattices
title_full_unstemmed Designed and biologically active protein lattices
title_sort designed and biologically active protein lattices
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/fff27e4143024037b51fe7d8436773cc
work_keys_str_mv AT shihtingwang designedandbiologicallyactiveproteinlattices
AT brianminevich designedandbiologicallyactiveproteinlattices
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AT dmytronykypanchuk designedandbiologicallyactiveproteinlattices
AT jamesbyrnes designedandbiologicallyactiveproteinlattices
AT wuliu designedandbiologicallyactiveproteinlattices
AT levbershadsky designedandbiologicallyactiveproteinlattices
AT qunliu designedandbiologicallyactiveproteinlattices
AT tongwang designedandbiologicallyactiveproteinlattices
AT gangren designedandbiologicallyactiveproteinlattices
AT oleggang designedandbiologicallyactiveproteinlattices
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