Colorectal Injuries in Minimal Invasive Urologic Surgery

Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histo...

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Autores principales: Mohammad Mehdi Hosseini, Alireza Aminsharifi, Mohsen Rastegari, Ali Eslahi, Shahrokh Jahanbini
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Publicado: Shiraz University of Medical Sciences 2014
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spelling oai:doaj.org-article:fff909cbd7cd476fa3df4182e4bb91cb2021-11-14T07:57:19ZColorectal Injuries in Minimal Invasive Urologic Surgery2783-243010.17795/acr-17983https://doaj.org/article/fff909cbd7cd476fa3df4182e4bb91cb2014-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_45463_0b1ed0f70bcdfd5878d186df3c6149d8.pdfhttps://doaj.org/toc/2783-2430Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histological outcomes of applying human amniotic membrane (HAM) in colonic anastomosis in dogs. Materials and Methods Eight cross-breed male dogs were divided into two equal groups. After anesthesia and exploration, 5cm of left colon was resected, and end-to-end anastomosis was performed in a single layer. In the treatment group (B), HAM patch measuring 2×3 cm was wrapped around the anastomotic line. Mann-Whitney U test was used to compare the results in the two groups due to small sample size, and normal distribution of data was examined using the kolmogorov-simirnov test (P = 0.03). Results Modified scoring system for surgical wound healing was used to identify the grade of healing in all samples. The healing score was significantly higher in the HAM group (P = 0.01). Conclusions HAM plays a positive role in healing of colonic anastomosis, and would lead to better histological outcomes compared to simple anastomosis in dogs.Mohammad Mehdi HosseiniAlireza AminsharifiMohsen RastegariAli EslahiShahrokh JahanbiniShiraz University of Medical Sciencesarticleurologic surgical procedurescolorectal surgerycomplicationsMedicineRENIranian Journal of Colorectal Research, Vol 2, Iss 2, Pp 0-0 (2014)
institution DOAJ
collection DOAJ
language EN
topic urologic surgical procedures
colorectal surgery
complications
Medicine
R
spellingShingle urologic surgical procedures
colorectal surgery
complications
Medicine
R
Mohammad Mehdi Hosseini
Alireza Aminsharifi
Mohsen Rastegari
Ali Eslahi
Shahrokh Jahanbini
Colorectal Injuries in Minimal Invasive Urologic Surgery
description Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histological outcomes of applying human amniotic membrane (HAM) in colonic anastomosis in dogs. Materials and Methods Eight cross-breed male dogs were divided into two equal groups. After anesthesia and exploration, 5cm of left colon was resected, and end-to-end anastomosis was performed in a single layer. In the treatment group (B), HAM patch measuring 2×3 cm was wrapped around the anastomotic line. Mann-Whitney U test was used to compare the results in the two groups due to small sample size, and normal distribution of data was examined using the kolmogorov-simirnov test (P = 0.03). Results Modified scoring system for surgical wound healing was used to identify the grade of healing in all samples. The healing score was significantly higher in the HAM group (P = 0.01). Conclusions HAM plays a positive role in healing of colonic anastomosis, and would lead to better histological outcomes compared to simple anastomosis in dogs.
format article
author Mohammad Mehdi Hosseini
Alireza Aminsharifi
Mohsen Rastegari
Ali Eslahi
Shahrokh Jahanbini
author_facet Mohammad Mehdi Hosseini
Alireza Aminsharifi
Mohsen Rastegari
Ali Eslahi
Shahrokh Jahanbini
author_sort Mohammad Mehdi Hosseini
title Colorectal Injuries in Minimal Invasive Urologic Surgery
title_short Colorectal Injuries in Minimal Invasive Urologic Surgery
title_full Colorectal Injuries in Minimal Invasive Urologic Surgery
title_fullStr Colorectal Injuries in Minimal Invasive Urologic Surgery
title_full_unstemmed Colorectal Injuries in Minimal Invasive Urologic Surgery
title_sort colorectal injuries in minimal invasive urologic surgery
publisher Shiraz University of Medical Sciences
publishDate 2014
url https://doaj.org/article/fff909cbd7cd476fa3df4182e4bb91cb
work_keys_str_mv AT mohammadmehdihosseini colorectalinjuriesinminimalinvasiveurologicsurgery
AT alirezaaminsharifi colorectalinjuriesinminimalinvasiveurologicsurgery
AT mohsenrastegari colorectalinjuriesinminimalinvasiveurologicsurgery
AT alieslahi colorectalinjuriesinminimalinvasiveurologicsurgery
AT shahrokhjahanbini colorectalinjuriesinminimalinvasiveurologicsurgery
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