Deficits in executive and memory processes in delusional disorder: a case-control study.

<h4>Objective</h4>Delusional disorder has been traditionally considered a psychotic syndrome that does not evolve to cognitive deterioration. However, to date, very little empirical research has been done to explore cognitive executive components and memory processes in Delusional Disord...

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Autores principales:	Inmaculada Ibanez-Casas, Enrique De Portugal, Nieves Gonzalez, Kathryn A McKenney, Josep M Haro, Judith Usall, Miguel Perez-Garcia, Jorge A Cervilla
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fffbb8b6171d4516ab8e05d7956d02c2
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spelling	oai:doaj.org-article:fffbb8b6171d4516ab8e05d7956d02c22021-11-18T07:39:09ZDeficits in executive and memory processes in delusional disorder: a case-control study.1932-620310.1371/journal.pone.0067341https://doaj.org/article/fffbb8b6171d4516ab8e05d7956d02c22013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23844005/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>Delusional disorder has been traditionally considered a psychotic syndrome that does not evolve to cognitive deterioration. However, to date, very little empirical research has been done to explore cognitive executive components and memory processes in Delusional Disorder patients. This study will investigate whether patients with delusional disorder are intact in both executive function components (such as flexibility, impulsivity and updating components) and memory processes (such as immediate, short term and long term recall, learning and recognition).<h4>Methods</h4>A large sample of patients with delusional disorder (n = 86) and a group of healthy controls (n = 343) were compared with regard to their performance in a broad battery of neuropsychological tests including Trail Making Test, Wisconsin Card Sorting Test, Colour-Word Stroop Test, and Complutense Verbal Learning Test (TAVEC).<h4>Results</h4>When compared to controls, cases of delusional disorder showed a significantly poorer performance in most cognitive tests. Thus, we demonstrate deficits in flexibility, impulsivity and updating components of executive functions as well as in memory processes. These findings held significant after taking into account sex, age, educational level and premorbid IQ.<h4>Conclusions</h4>Our results do not support the traditional notion of patients with delusional disorder being cognitively intact.Inmaculada Ibanez-CasasEnrique De PortugalNieves GonzalezKathryn A McKenneyJosep M HaroJudith UsallMiguel Perez-GarciaJorge A CervillaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 7, p e67341 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Inmaculada Ibanez-Casas Enrique De Portugal Nieves Gonzalez Kathryn A McKenney Josep M Haro Judith Usall Miguel Perez-Garcia Jorge A Cervilla Deficits in executive and memory processes in delusional disorder: a case-control study.
description	<h4>Objective</h4>Delusional disorder has been traditionally considered a psychotic syndrome that does not evolve to cognitive deterioration. However, to date, very little empirical research has been done to explore cognitive executive components and memory processes in Delusional Disorder patients. This study will investigate whether patients with delusional disorder are intact in both executive function components (such as flexibility, impulsivity and updating components) and memory processes (such as immediate, short term and long term recall, learning and recognition).<h4>Methods</h4>A large sample of patients with delusional disorder (n = 86) and a group of healthy controls (n = 343) were compared with regard to their performance in a broad battery of neuropsychological tests including Trail Making Test, Wisconsin Card Sorting Test, Colour-Word Stroop Test, and Complutense Verbal Learning Test (TAVEC).<h4>Results</h4>When compared to controls, cases of delusional disorder showed a significantly poorer performance in most cognitive tests. Thus, we demonstrate deficits in flexibility, impulsivity and updating components of executive functions as well as in memory processes. These findings held significant after taking into account sex, age, educational level and premorbid IQ.<h4>Conclusions</h4>Our results do not support the traditional notion of patients with delusional disorder being cognitively intact.
format	article
author	Inmaculada Ibanez-Casas Enrique De Portugal Nieves Gonzalez Kathryn A McKenney Josep M Haro Judith Usall Miguel Perez-Garcia Jorge A Cervilla
author_facet	Inmaculada Ibanez-Casas Enrique De Portugal Nieves Gonzalez Kathryn A McKenney Josep M Haro Judith Usall Miguel Perez-Garcia Jorge A Cervilla
author_sort	Inmaculada Ibanez-Casas
title	Deficits in executive and memory processes in delusional disorder: a case-control study.
title_short	Deficits in executive and memory processes in delusional disorder: a case-control study.
title_full	Deficits in executive and memory processes in delusional disorder: a case-control study.
title_fullStr	Deficits in executive and memory processes in delusional disorder: a case-control study.
title_full_unstemmed	Deficits in executive and memory processes in delusional disorder: a case-control study.
title_sort	deficits in executive and memory processes in delusional disorder: a case-control study.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/fffbb8b6171d4516ab8e05d7956d02c2
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Deficits in executive and memory processes in delusional disorder: a case-control study.

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