Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico

Background: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in...

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Autores principales: Csendes J,Attila, Burdiles P,Patricio, Maluenda G,Fernando, Cortés D,Claudio, Korn B,Owen, Rojas C,Jorge, Tepper J,Patricio, Huertas M,César, Sagastume G,Héctor, Puente Q,Guillermo, Quezada M,Fernando, Csendes G,Paula
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 1998
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871998000700004
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spelling oai:scielo:S0034-988719980007000041999-06-15Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológicoCsendes J,AttilaBurdiles P,PatricioMaluenda G,FernandoCortés D,ClaudioKorn B,OwenRojas C,JorgeTepper J,PatricioHuertas M,CésarSagastume G,HéctorPuente Q,GuillermoQuezada M,FernandoCsendes G,Paula Esophageal motility disorders Esophagitis, peptic Gastro esophageal reflux Manometry Background: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in a prospective protocol that included clinical analysis, manometry and endoscopy in all patients, barium swallow in 427, scintigraphy in 195, acid reflux test in 359, 24 h pH in 175, and differential potential of gastroesophageal mucosa in 73 patients. Results: There was no correlation between the severity of symptoms and the endoscopical severity. Patients with Barret esophagus were 12 years older, were male in a greater proportion and had a higher proportion of manometrically incompetent sphincters than patients with esophageal reflux but without esophagitis or with erosive esophagitis. Severity of acid reflux, measured with 24 h pH monitoring was proportional to the endoscopical damage of the mucosa. There was a close relationship between the mucosal change limit determined with differential potentials and with endoscopy. No short esophagi were found. Conclusions: Patients with symptoms of gastroesophageal reflux must be assessed using several objective measures to determine the severity of their pathological alterations.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.126 n.7 19981998-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871998000700004es10.4067/S0034-98871998000700004
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Esophageal motility disorders
Esophagitis, peptic
Gastro esophageal reflux
Manometry
spellingShingle Esophageal motility disorders
Esophagitis, peptic
Gastro esophageal reflux
Manometry
Csendes J,Attila
Burdiles P,Patricio
Maluenda G,Fernando
Cortés D,Claudio
Korn B,Owen
Rojas C,Jorge
Tepper J,Patricio
Huertas M,César
Sagastume G,Héctor
Puente Q,Guillermo
Quezada M,Fernando
Csendes G,Paula
Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
description Background: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in a prospective protocol that included clinical analysis, manometry and endoscopy in all patients, barium swallow in 427, scintigraphy in 195, acid reflux test in 359, 24 h pH in 175, and differential potential of gastroesophageal mucosa in 73 patients. Results: There was no correlation between the severity of symptoms and the endoscopical severity. Patients with Barret esophagus were 12 years older, were male in a greater proportion and had a higher proportion of manometrically incompetent sphincters than patients with esophageal reflux but without esophagitis or with erosive esophagitis. Severity of acid reflux, measured with 24 h pH monitoring was proportional to the endoscopical damage of the mucosa. There was a close relationship between the mucosal change limit determined with differential potentials and with endoscopy. No short esophagi were found. Conclusions: Patients with symptoms of gastroesophageal reflux must be assessed using several objective measures to determine the severity of their pathological alterations.
author Csendes J,Attila
Burdiles P,Patricio
Maluenda G,Fernando
Cortés D,Claudio
Korn B,Owen
Rojas C,Jorge
Tepper J,Patricio
Huertas M,César
Sagastume G,Héctor
Puente Q,Guillermo
Quezada M,Fernando
Csendes G,Paula
author_facet Csendes J,Attila
Burdiles P,Patricio
Maluenda G,Fernando
Cortés D,Claudio
Korn B,Owen
Rojas C,Jorge
Tepper J,Patricio
Huertas M,César
Sagastume G,Héctor
Puente Q,Guillermo
Quezada M,Fernando
Csendes G,Paula
author_sort Csendes J,Attila
title Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
title_short Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
title_full Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
title_fullStr Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
title_full_unstemmed Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
title_sort características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
publisher Sociedad Médica de Santiago
publishDate 1998
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871998000700004
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