Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico
Background: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in...
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Sociedad Médica de Santiago
1998
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oai:scielo:S0034-988719980007000041999-06-15Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológicoCsendes J,AttilaBurdiles P,PatricioMaluenda G,FernandoCortés D,ClaudioKorn B,OwenRojas C,JorgeTepper J,PatricioHuertas M,CésarSagastume G,HéctorPuente Q,GuillermoQuezada M,FernandoCsendes G,Paula Esophageal motility disorders Esophagitis, peptic Gastro esophageal reflux Manometry Background: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in a prospective protocol that included clinical analysis, manometry and endoscopy in all patients, barium swallow in 427, scintigraphy in 195, acid reflux test in 359, 24 h pH in 175, and differential potential of gastroesophageal mucosa in 73 patients. Results: There was no correlation between the severity of symptoms and the endoscopical severity. Patients with Barret esophagus were 12 years older, were male in a greater proportion and had a higher proportion of manometrically incompetent sphincters than patients with esophageal reflux but without esophagitis or with erosive esophagitis. Severity of acid reflux, measured with 24 h pH monitoring was proportional to the endoscopical damage of the mucosa. There was a close relationship between the mucosal change limit determined with differential potentials and with endoscopy. No short esophagi were found. Conclusions: Patients with symptoms of gastroesophageal reflux must be assessed using several objective measures to determine the severity of their pathological alterations.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.126 n.7 19981998-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871998000700004es10.4067/S0034-98871998000700004 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Esophageal motility disorders Esophagitis, peptic Gastro esophageal reflux Manometry |
spellingShingle |
Esophageal motility disorders Esophagitis, peptic Gastro esophageal reflux Manometry Csendes J,Attila Burdiles P,Patricio Maluenda G,Fernando Cortés D,Claudio Korn B,Owen Rojas C,Jorge Tepper J,Patricio Huertas M,César Sagastume G,Héctor Puente Q,Guillermo Quezada M,Fernando Csendes G,Paula Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico |
description |
Background: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in a prospective protocol that included clinical analysis, manometry and endoscopy in all patients, barium swallow in 427, scintigraphy in 195, acid reflux test in 359, 24 h pH in 175, and differential potential of gastroesophageal mucosa in 73 patients. Results: There was no correlation between the severity of symptoms and the endoscopical severity. Patients with Barret esophagus were 12 years older, were male in a greater proportion and had a higher proportion of manometrically incompetent sphincters than patients with esophageal reflux but without esophagitis or with erosive esophagitis. Severity of acid reflux, measured with 24 h pH monitoring was proportional to the endoscopical damage of the mucosa. There was a close relationship between the mucosal change limit determined with differential potentials and with endoscopy. No short esophagi were found. Conclusions: Patients with symptoms of gastroesophageal reflux must be assessed using several objective measures to determine the severity of their pathological alterations. |
author |
Csendes J,Attila Burdiles P,Patricio Maluenda G,Fernando Cortés D,Claudio Korn B,Owen Rojas C,Jorge Tepper J,Patricio Huertas M,César Sagastume G,Héctor Puente Q,Guillermo Quezada M,Fernando Csendes G,Paula |
author_facet |
Csendes J,Attila Burdiles P,Patricio Maluenda G,Fernando Cortés D,Claudio Korn B,Owen Rojas C,Jorge Tepper J,Patricio Huertas M,César Sagastume G,Héctor Puente Q,Guillermo Quezada M,Fernando Csendes G,Paula |
author_sort |
Csendes J,Attila |
title |
Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico |
title_short |
Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico |
title_full |
Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico |
title_fullStr |
Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico |
title_full_unstemmed |
Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico |
title_sort |
características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico |
publisher |
Sociedad Médica de Santiago |
publishDate |
1998 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871998000700004 |
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