Helicobacter pylori: La revolución bacteriológica
The finding of H pylori in the gastric mucosa has changed the understanding of the pathogenesis of common diseases of the stomach and duodenum. The bacteria causes acute and chronic gastritis and is the precursor of peptic ulcers, gastric lymphoma and gastric cancer. The most common test used to dia...
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| Lenguaje: | Spanish / Castilian |
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| Publicado: |
Sociedad Médica de Santiago
1999
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| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999000800001 |
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oai:scielo:S0034-988719990008000012005-11-14Helicobacter pylori: La revolución bacteriológica Antibiotics, combined Gastric mucosa Gastritis Helicobacter pylori Lymphoma Peptic ulcer Vaccines The finding of H pylori in the gastric mucosa has changed the understanding of the pathogenesis of common diseases of the stomach and duodenum. The bacteria causes acute and chronic gastritis and is the precursor of peptic ulcers, gastric lymphoma and gastric cancer. The most common test used to diagnose the infection is the urease test on a gastric biopsy but an endoscopy must be performed to obtain the biopsy. Determination of serum levels of IgG appears the most suitable test to perform in large population studies. Patients with peptic ulcers, gastric lymphoma and early gastric cancer should be treated. Combinations of antibiotics such as amoxicillin, chlaritromycin and a proton pump inhibitor have yielded the best results in erradicating H pylori. Unfortunately this therapy is expensive and new combinations should be explored. Vaccination should be the treatment of choice for prevention and erradication in countries like Chile with high infection rate. Preliminary results are encouraging.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.127 n.8 19991999-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999000800001es10.4067/S0034-98871999000800001 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Antibiotics, combined Gastric mucosa Gastritis Helicobacter pylori Lymphoma Peptic ulcer Vaccines |
| spellingShingle |
Antibiotics, combined Gastric mucosa Gastritis Helicobacter pylori Lymphoma Peptic ulcer Vaccines Helicobacter pylori: La revolución bacteriológica |
| description |
The finding of H pylori in the gastric mucosa has changed the understanding of the pathogenesis of common diseases of the stomach and duodenum. The bacteria causes acute and chronic gastritis and is the precursor of peptic ulcers, gastric lymphoma and gastric cancer. The most common test used to diagnose the infection is the urease test on a gastric biopsy but an endoscopy must be performed to obtain the biopsy. Determination of serum levels of IgG appears the most suitable test to perform in large population studies. Patients with peptic ulcers, gastric lymphoma and early gastric cancer should be treated. Combinations of antibiotics such as amoxicillin, chlaritromycin and a proton pump inhibitor have yielded the best results in erradicating H pylori. Unfortunately this therapy is expensive and new combinations should be explored. Vaccination should be the treatment of choice for prevention and erradication in countries like Chile with high infection rate. Preliminary results are encouraging. |
| title |
Helicobacter pylori: La revolución bacteriológica |
| title_short |
Helicobacter pylori: La revolución bacteriológica |
| title_full |
Helicobacter pylori: La revolución bacteriológica |
| title_fullStr |
Helicobacter pylori: La revolución bacteriológica |
| title_full_unstemmed |
Helicobacter pylori: La revolución bacteriológica |
| title_sort |
helicobacter pylori: la revolución bacteriológica |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
1999 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999000800001 |
| _version_ |
1718435872502710272 |