Hiponatremia e hipokalemia graves, recientes, asociadas a hidroclorotiazida, enalaprila y citalopram.: Caso clínico

We report a 72 years old hypertensive female, treated with enalapril 10 mg/day and hydrochlorothiazide 25 mg/day during three years. She presented a depressive disorder and cytalopram was prescribed in a dose of 10 mg/day. Two weeks before admission, a serum electrolyte analysis disclosed normal res...

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Autores principales: Riquelme P,Arnoldo, Méndez R,Felipe, Ortiz M,Ana Mireya, Müller O,Hans, Campos O,Carolina, Rocha R,Víctor, Valdivieso D,Andrés
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 1999
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001000010
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Sumario:We report a 72 years old hypertensive female, treated with enalapril 10 mg/day and hydrochlorothiazide 25 mg/day during three years. She presented a depressive disorder and cytalopram was prescribed in a dose of 10 mg/day. Two weeks before admission, a serum electrolyte analysis disclosed normal results and the cytalopram dose was increased to 20 mg/day. The patient was admitted with a hyponatremic encephalopathy with a plasma sodium of 100 mEq/L and a plasma potassium of 2.0 mEq/L. Cytalopram, enalapril and hydrochlorothiazide were discontinued, hypertonic NaCl and KCl were administered. The patient had a favorable evolution with a remarkable improvement of her symptoms.