Emergencia de resistencia a macrólidos en Streptococcus pyogenes
Background: Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, suc...
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Sociedad Médica de Santiago
1999
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oai:scielo:S0034-988719990012000052000-04-05Emergencia de resistencia a macrólidos en Streptococcus pyogenesVinagre del P,ClaudiaCifuentes D,MarcelaValdivieso R,FranciscaOjeda S,AliciaPrado J,Valeria Antibiotics Antibiotics, Macrolide Bacterial Infections Gram-Positive, Bacterial Infections Background: Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, such as erythromycin, new macrolides and cephalosporins. Nevertheless, resistant strains are appearing due to the indiscriminate use of macrolides. Aim: To assess present antimicrobial susceptibility of S Pyogenes strains isolated from chilean patients. Material and Methods: The susceptibility to penicillin, macrolides, clindamycin, cephalotin and vancomycin of 153 S Pyogenes strains, obtained from different health centers of the Metropolitan Region and isolated between 1996 and 1998, was assessed using the Kirby-Bauer method. Agar dilution minimal inhibitory concentration was then determined to macrolide resistant strains. Results: All strains were susceptible to penicillin. There was a 7.2% cross-resistance to macrolides. Conclusions: These results confirm that S Pyogenes resistance to macrolides has increased considerably in the Metropolitan Region of Chile during the last years.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.127 n.12 19991999-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001200005es10.4067/S0034-98871999001200005 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Antibiotics Antibiotics, Macrolide Bacterial Infections Gram-Positive, Bacterial Infections |
spellingShingle |
Antibiotics Antibiotics, Macrolide Bacterial Infections Gram-Positive, Bacterial Infections Vinagre del P,Claudia Cifuentes D,Marcela Valdivieso R,Francisca Ojeda S,Alicia Prado J,Valeria Emergencia de resistencia a macrólidos en Streptococcus pyogenes |
description |
Background: Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, such as erythromycin, new macrolides and cephalosporins. Nevertheless, resistant strains are appearing due to the indiscriminate use of macrolides. Aim: To assess present antimicrobial susceptibility of S Pyogenes strains isolated from chilean patients. Material and Methods: The susceptibility to penicillin, macrolides, clindamycin, cephalotin and vancomycin of 153 S Pyogenes strains, obtained from different health centers of the Metropolitan Region and isolated between 1996 and 1998, was assessed using the Kirby-Bauer method. Agar dilution minimal inhibitory concentration was then determined to macrolide resistant strains. Results: All strains were susceptible to penicillin. There was a 7.2% cross-resistance to macrolides. Conclusions: These results confirm that S Pyogenes resistance to macrolides has increased considerably in the Metropolitan Region of Chile during the last years. |
author |
Vinagre del P,Claudia Cifuentes D,Marcela Valdivieso R,Francisca Ojeda S,Alicia Prado J,Valeria |
author_facet |
Vinagre del P,Claudia Cifuentes D,Marcela Valdivieso R,Francisca Ojeda S,Alicia Prado J,Valeria |
author_sort |
Vinagre del P,Claudia |
title |
Emergencia de resistencia a macrólidos en Streptococcus pyogenes |
title_short |
Emergencia de resistencia a macrólidos en Streptococcus pyogenes |
title_full |
Emergencia de resistencia a macrólidos en Streptococcus pyogenes |
title_fullStr |
Emergencia de resistencia a macrólidos en Streptococcus pyogenes |
title_full_unstemmed |
Emergencia de resistencia a macrólidos en Streptococcus pyogenes |
title_sort |
emergencia de resistencia a macrólidos en streptococcus pyogenes |
publisher |
Sociedad Médica de Santiago |
publishDate |
1999 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001200005 |
work_keys_str_mv |
AT vinagredelpclaudia emergenciaderesistenciaamacrolidosenstreptococcuspyogenes AT cifuentesdmarcela emergenciaderesistenciaamacrolidosenstreptococcuspyogenes AT valdiviesorfrancisca emergenciaderesistenciaamacrolidosenstreptococcuspyogenes AT ojedasalicia emergenciaderesistenciaamacrolidosenstreptococcuspyogenes AT pradojvaleria emergenciaderesistenciaamacrolidosenstreptococcuspyogenes |
_version_ |
1718435894236545024 |