Emergencia de resistencia a macrólidos en Streptococcus pyogenes

Background: Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, suc...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vinagre del P,Claudia, Cifuentes D,Marcela, Valdivieso R,Francisca, Ojeda S,Alicia, Prado J,Valeria
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 1999
Materias:
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001200005
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:scielo:S0034-98871999001200005
record_format dspace
spelling oai:scielo:S0034-988719990012000052000-04-05Emergencia de resistencia a macrólidos en Streptococcus pyogenesVinagre del P,ClaudiaCifuentes D,MarcelaValdivieso R,FranciscaOjeda S,AliciaPrado J,Valeria Antibiotics Antibiotics, Macrolide Bacterial Infections Gram-Positive, Bacterial Infections Background: Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, such as erythromycin, new macrolides and cephalosporins. Nevertheless, resistant strains are appearing due to the indiscriminate use of macrolides. Aim: To assess present antimicrobial susceptibility of S Pyogenes strains isolated from chilean patients. Material and Methods: The susceptibility to penicillin, macrolides, clindamycin, cephalotin and vancomycin of 153 S Pyogenes strains, obtained from different health centers of the Metropolitan Region and isolated between 1996 and 1998, was assessed using the Kirby-Bauer method. Agar dilution minimal inhibitory concentration was then determined to macrolide resistant strains. Results: All strains were susceptible to penicillin. There was a 7.2% cross-resistance to macrolides. Conclusions: These results confirm that S Pyogenes resistance to macrolides has increased considerably in the Metropolitan Region of Chile during the last years.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.127 n.12 19991999-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001200005es10.4067/S0034-98871999001200005
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Antibiotics
Antibiotics, Macrolide
Bacterial Infections
Gram-Positive, Bacterial Infections
spellingShingle Antibiotics
Antibiotics, Macrolide
Bacterial Infections
Gram-Positive, Bacterial Infections
Vinagre del P,Claudia
Cifuentes D,Marcela
Valdivieso R,Francisca
Ojeda S,Alicia
Prado J,Valeria
Emergencia de resistencia a macrólidos en Streptococcus pyogenes
description Background: Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, such as erythromycin, new macrolides and cephalosporins. Nevertheless, resistant strains are appearing due to the indiscriminate use of macrolides. Aim: To assess present antimicrobial susceptibility of S Pyogenes strains isolated from chilean patients. Material and Methods: The susceptibility to penicillin, macrolides, clindamycin, cephalotin and vancomycin of 153 S Pyogenes strains, obtained from different health centers of the Metropolitan Region and isolated between 1996 and 1998, was assessed using the Kirby-Bauer method. Agar dilution minimal inhibitory concentration was then determined to macrolide resistant strains. Results: All strains were susceptible to penicillin. There was a 7.2% cross-resistance to macrolides. Conclusions: These results confirm that S Pyogenes resistance to macrolides has increased considerably in the Metropolitan Region of Chile during the last years.
author Vinagre del P,Claudia
Cifuentes D,Marcela
Valdivieso R,Francisca
Ojeda S,Alicia
Prado J,Valeria
author_facet Vinagre del P,Claudia
Cifuentes D,Marcela
Valdivieso R,Francisca
Ojeda S,Alicia
Prado J,Valeria
author_sort Vinagre del P,Claudia
title Emergencia de resistencia a macrólidos en Streptococcus pyogenes
title_short Emergencia de resistencia a macrólidos en Streptococcus pyogenes
title_full Emergencia de resistencia a macrólidos en Streptococcus pyogenes
title_fullStr Emergencia de resistencia a macrólidos en Streptococcus pyogenes
title_full_unstemmed Emergencia de resistencia a macrólidos en Streptococcus pyogenes
title_sort emergencia de resistencia a macrólidos en streptococcus pyogenes
publisher Sociedad Médica de Santiago
publishDate 1999
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001200005
work_keys_str_mv AT vinagredelpclaudia emergenciaderesistenciaamacrolidosenstreptococcuspyogenes
AT cifuentesdmarcela emergenciaderesistenciaamacrolidosenstreptococcuspyogenes
AT valdiviesorfrancisca emergenciaderesistenciaamacrolidosenstreptococcuspyogenes
AT ojedasalicia emergenciaderesistenciaamacrolidosenstreptococcuspyogenes
AT pradojvaleria emergenciaderesistenciaamacrolidosenstreptococcuspyogenes
_version_ 1718435894236545024