Asociación obesidad y leptina en tres poblaciones aborígenes de Chile

Background: Although there is a clear relationship between body mass index and leptin levels, few authors have addressed the possible influence of ethnic factors on these levels. Aim: To measure serum leptin in three different Chilean aboriginal populations. Subjects and methods: Fasting serum lepti...

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Autores principales:	Pérez B,Francisco, Santos M,José Luis, Albala B,Cecilia, Calvillán C,Marcelo, Carrasco P,Elena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2000
Materias:	Ethnic groups Leptin, Obesity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100006
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spelling	oai:scielo:S0034-988720000001000062000-05-25Asociación obesidad y leptina en tres poblaciones aborígenes de ChilePérez B,FranciscoSantos M,José LuisAlbala B,CeciliaCalvillán C,MarceloCarrasco P,Elena Ethnic groups Leptin, Obesity Background: Although there is a clear relationship between body mass index and leptin levels, few authors have addressed the possible influence of ethnic factors on these levels. Aim: To measure serum leptin in three different Chilean aboriginal populations. Subjects and methods: Fasting serum leptin and insulin levels were measured by radioimmunoassay in 345 rural mapuche individuals, 247 rural aymara subjects and 162 urban mapuche subjects. A body mass index of 27.5 kg/m2 was used as cutoff point to classify study subjects. Results: Among the three ethnic groups, women had serum leptin levels three times higher than men. In all three ethnic groups, there was a significant association between leptin levels, body mass index and gender (r2= 0.32 and 0.5 p <0.001, in rural mapuche, r2= 0.32 and 0.5 p <0.001, in aymara and r2= 0.24 and 0.49, p <0.001 in urban mapuche populations). No differences in leptin levels were observed for the interaction between age and insulin. The increments per quartile in leptin levels were lower among mapuche than aymara individuals. Conclusions: Rural mapuche individuals have a high frequency of obesity. However their leptin levels are lower than those of aymara or urban mapuche populations. The higher leptin levels observed in urban mapuche subjects could be due to environmental influences. (Rev Méd Chile 2000; 128: 45-52)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.1 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100006es10.4067/S0034-98872000000100006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Ethnic groups Leptin, Obesity
spellingShingle	Ethnic groups Leptin, Obesity Pérez B,Francisco Santos M,José Luis Albala B,Cecilia Calvillán C,Marcelo Carrasco P,Elena Asociación obesidad y leptina en tres poblaciones aborígenes de Chile
description	Background: Although there is a clear relationship between body mass index and leptin levels, few authors have addressed the possible influence of ethnic factors on these levels. Aim: To measure serum leptin in three different Chilean aboriginal populations. Subjects and methods: Fasting serum leptin and insulin levels were measured by radioimmunoassay in 345 rural mapuche individuals, 247 rural aymara subjects and 162 urban mapuche subjects. A body mass index of 27.5 kg/m2 was used as cutoff point to classify study subjects. Results: Among the three ethnic groups, women had serum leptin levels three times higher than men. In all three ethnic groups, there was a significant association between leptin levels, body mass index and gender (r2= 0.32 and 0.5 p <0.001, in rural mapuche, r2= 0.32 and 0.5 p <0.001, in aymara and r2= 0.24 and 0.49, p <0.001 in urban mapuche populations). No differences in leptin levels were observed for the interaction between age and insulin. The increments per quartile in leptin levels were lower among mapuche than aymara individuals. Conclusions: Rural mapuche individuals have a high frequency of obesity. However their leptin levels are lower than those of aymara or urban mapuche populations. The higher leptin levels observed in urban mapuche subjects could be due to environmental influences. (Rev Méd Chile 2000; 128: 45-52)
author	Pérez B,Francisco Santos M,José Luis Albala B,Cecilia Calvillán C,Marcelo Carrasco P,Elena
author_facet	Pérez B,Francisco Santos M,José Luis Albala B,Cecilia Calvillán C,Marcelo Carrasco P,Elena
author_sort	Pérez B,Francisco
title	Asociación obesidad y leptina en tres poblaciones aborígenes de Chile
title_short	Asociación obesidad y leptina en tres poblaciones aborígenes de Chile
title_full	Asociación obesidad y leptina en tres poblaciones aborígenes de Chile
title_fullStr	Asociación obesidad y leptina en tres poblaciones aborígenes de Chile
title_full_unstemmed	Asociación obesidad y leptina en tres poblaciones aborígenes de Chile
title_sort	asociación obesidad y leptina en tres poblaciones aborígenes de chile
publisher	Sociedad Médica de Santiago
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100006
work_keys_str_mv	AT perezbfrancisco asociacionobesidadyleptinaentrespoblacionesaborigenesdechile AT santosmjoseluis asociacionobesidadyleptinaentrespoblacionesaborigenesdechile AT albalabcecilia asociacionobesidadyleptinaentrespoblacionesaborigenesdechile AT calvillancmarcelo asociacionobesidadyleptinaentrespoblacionesaborigenesdechile AT carrascopelena asociacionobesidadyleptinaentrespoblacionesaborigenesdechile
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Asociación obesidad y leptina en tres poblaciones aborígenes de Chile

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