Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica

Background: Third generation beta blockers have an intrinsic simpatico-mimetic activity and are cardioselective. Therefore, they should not have adverse bronchial effects and could even have a slight bronchodilator activity. Aim: To test the efficacy and safety of celiprolol in hypertensive patients...

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Autores principales:	Chahuán Y,Marco, Corradi H,Luis, Román A,Oscar, Bravo G,Cecilia
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2000
Materias:	Adrenergic beta-antagonists Celiprolol Lung diseases, obstructive
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100008
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spelling	oai:scielo:S0034-988720000001000082000-05-25Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónicaChahuán Y,MarcoCorradi H,LuisRomán A,OscarBravo G,Cecilia Adrenergic beta-antagonists Celiprolol Lung diseases, obstructive Background: Third generation beta blockers have an intrinsic simpatico-mimetic activity and are cardioselective. Therefore, they should not have adverse bronchial effects and could even have a slight bronchodilator activity. Aim: To test the efficacy and safety of celiprolol in hypertensive patients with chronic obstructive lung disease. Patients and methods: Uncomplicated hypertensive patients with chronic obstructive lung disease received celiprolol during 12 weeks. They were subjected to monthly clinical assessment and ventilatory function was measured on the basal period and at the end of the trial. Results: During the study period, blood pressure fell significantly from 179±6/112±8 to 161±4,7/98±1.6 mmHg. No changes were observed in forced expiratory volume in 1 s or in forced expiratory flow between 25 and 75% of the vital capacity. No subjective changes in respiratory function were reported during the trial. Conclusions: No changes in ventilatory function were observed in these patients with chronic obstructive lung disease, treated with celiprolol during 12 weeks. (Rev Méd Chile 2000; 128: 59-63)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.1 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100008es10.4067/S0034-98872000000100008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Adrenergic beta-antagonists Celiprolol Lung diseases, obstructive
spellingShingle	Adrenergic beta-antagonists Celiprolol Lung diseases, obstructive Chahuán Y,Marco Corradi H,Luis Román A,Oscar Bravo G,Cecilia Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica
description	Background: Third generation beta blockers have an intrinsic simpatico-mimetic activity and are cardioselective. Therefore, they should not have adverse bronchial effects and could even have a slight bronchodilator activity. Aim: To test the efficacy and safety of celiprolol in hypertensive patients with chronic obstructive lung disease. Patients and methods: Uncomplicated hypertensive patients with chronic obstructive lung disease received celiprolol during 12 weeks. They were subjected to monthly clinical assessment and ventilatory function was measured on the basal period and at the end of the trial. Results: During the study period, blood pressure fell significantly from 179±6/112±8 to 161±4,7/98±1.6 mmHg. No changes were observed in forced expiratory volume in 1 s or in forced expiratory flow between 25 and 75% of the vital capacity. No subjective changes in respiratory function were reported during the trial. Conclusions: No changes in ventilatory function were observed in these patients with chronic obstructive lung disease, treated with celiprolol during 12 weeks. (Rev Méd Chile 2000; 128: 59-63)
author	Chahuán Y,Marco Corradi H,Luis Román A,Oscar Bravo G,Cecilia
author_facet	Chahuán Y,Marco Corradi H,Luis Román A,Oscar Bravo G,Cecilia
author_sort	Chahuán Y,Marco
title	Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica
title_short	Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica
title_full	Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica
title_fullStr	Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica
title_full_unstemmed	Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica
title_sort	seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica
publisher	Sociedad Médica de Santiago
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100008
work_keys_str_mv	AT chahuanymarco seguridadyeficaciadeceliprololenhipertensosconenfermedadpulmonarobstructivacronica AT corradihluis seguridadyeficaciadeceliprololenhipertensosconenfermedadpulmonarobstructivacronica AT romanaoscar seguridadyeficaciadeceliprololenhipertensosconenfermedadpulmonarobstructivacronica AT bravogcecilia seguridadyeficaciadeceliprololenhipertensosconenfermedadpulmonarobstructivacronica
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Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva crónica

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