El estudio HERS conmociona a la terapia de sustitución hormonal

El estudio HERS conmociona a la terapia de sustitución hormonal

Cardiovascular protection of hormonal replacement therapy was considered a fact. The effects of estrogens on lipid levels and vascular health gave biological support to estrogen cardioprotection. The recently published HERS study showing no protective effects of estrogen and progesterone replacement...

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Autores principales: Cano S,Antonio, Blümel M,Juan E
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2000
Materias:
Cardiovascular diseases
Estrogen replacement therapy
Hormone replacement therapy
post-menopausal
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100014
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spelling oai:scielo:S0034-988720000001000142000-05-25El estudio HERS conmociona a la terapia de sustitución hormonalCano S,AntonioBlümel M,Juan E Cardiovascular diseases Estrogen replacement therapy Hormone replacement therapy post-menopausal Cardiovascular protection of hormonal replacement therapy was considered a fact. The effects of estrogens on lipid levels and vascular health gave biological support to estrogen cardioprotection. The recently published HERS study showing no protective effects of estrogen and progesterone replacement therapy on the risk of myocardial infarction or coronary deaths is provoking perplexity. These surprising results may have several causes such as the use of progesterone, the associated use of cardioprotective agents or the short observation period. However, the study results scope is rectricted to secondary prevention. These cannot be extrapolated to frequent conditions of postmenopausal women such as primary prevention or sequential schemes. Likewise, this investigation underscores the importance of a critical and continued evaluation of apparently well established therapeutic approaches. (Rev Méd Chile 2000; 128: 98-104)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.1 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100014es10.4067/S0034-98872000000100014
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Cardiovascular diseases
Estrogen replacement therapy
Hormone replacement therapy
post-menopausal
spellingShingle Cardiovascular diseases
Estrogen replacement therapy
Hormone replacement therapy
post-menopausal
Cano S,Antonio
Blümel M,Juan E
El estudio HERS conmociona a la terapia de sustitución hormonal
description Cardiovascular protection of hormonal replacement therapy was considered a fact. The effects of estrogens on lipid levels and vascular health gave biological support to estrogen cardioprotection. The recently published HERS study showing no protective effects of estrogen and progesterone replacement therapy on the risk of myocardial infarction or coronary deaths is provoking perplexity. These surprising results may have several causes such as the use of progesterone, the associated use of cardioprotective agents or the short observation period. However, the study results scope is rectricted to secondary prevention. These cannot be extrapolated to frequent conditions of postmenopausal women such as primary prevention or sequential schemes. Likewise, this investigation underscores the importance of a critical and continued evaluation of apparently well established therapeutic approaches. (Rev Méd Chile 2000; 128: 98-104)
author Cano S,Antonio
Blümel M,Juan E
author_facet Cano S,Antonio
Blümel M,Juan E
author_sort Cano S,Antonio
title El estudio HERS conmociona a la terapia de sustitución hormonal
title_short El estudio HERS conmociona a la terapia de sustitución hormonal
title_full El estudio HERS conmociona a la terapia de sustitución hormonal
title_fullStr El estudio HERS conmociona a la terapia de sustitución hormonal
title_full_unstemmed El estudio HERS conmociona a la terapia de sustitución hormonal
title_sort el estudio hers conmociona a la terapia de sustitución hormonal
publisher Sociedad Médica de Santiago
publishDate 2000
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100014
work_keys_str_mv AT canosantonio elestudiohersconmocionaalaterapiadesustitucionhormonal
AT blumelmjuane elestudiohersconmocionaalaterapiadesustitucionhormonal
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