Factores causales de infertilidad masculina: Contribución del factor endocrino

Background: Male infertility is responsible for 35% of infertile couples. Aim: To investigate the causes of male infertility and the relative importance of endocrine factors. Patients and methods: Patients referred to an andrology clinic due to an abnormal spermiogram were studied. A testitular exam...

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Autores principales:	Devoto C,Enzo, Madariaga A,Marcia, Lioi C,Ximena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2000
Materias:	End crine diseases Infertility male Klinefelter syndrome Testicular diseases Testicular hormones
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000200008
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spelling	oai:scielo:S0034-988720000002000082014-05-06Factores causales de infertilidad masculina: Contribución del factor endocrinoDevoto C,EnzoMadariaga A,MarciaLioi C,Ximena End crine diseases Infertility male Klinefelter syndrome Testicular diseases Testicular hormones Background: Male infertility is responsible for 35% of infertile couples. Aim: To investigate the causes of male infertility and the relative importance of endocrine factors. Patients and methods: Patients referred to an andrology clinic due to an abnormal spermiogram were studied. A testitular examination, spermiogram and determination of FSH, LH, testosterone and prolactin were done to all. Testicular biopsy was done to patients with severe oligospermia or azoospermia. Causes of infertility were defined and classified as pretesticular, testicular, posttesticular or unclassified. Results: Two hundred fifty seven males were studied. In 3.5% of them, the cause of infertility was defined as pretesticular (that included hypothalamic and pituitary endocrine causes), in 66.9% it was classified as testicular, in 15.6% as posttesticular and in 14%, as unclassified. Thirty percent of infertility cases were idiopathic, 17.9% were associated to varicocele, 12.8% were associated to cryptorchidism, 8.9% to Klinefelter syndrome and 6.6% to exposure to toxic substances. In 50% of patients with cryptorchidism, this abnormality was found during the specialized andrological examination and referrals for surgical correction were made late. Two thirds of patients with Klinefelter syndrome were hypoandrogenic. Conclusions: Causes for male infertility should be investigated and diagnosed accurately. Primary hypoandrogenic testicular failures must be treated with hormone replacement therapyinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.2 20002000-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000200008es10.4067/S0034-98872000000200008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	End crine diseases Infertility male Klinefelter syndrome Testicular diseases Testicular hormones
spellingShingle	End crine diseases Infertility male Klinefelter syndrome Testicular diseases Testicular hormones Devoto C,Enzo Madariaga A,Marcia Lioi C,Ximena Factores causales de infertilidad masculina: Contribución del factor endocrino
description	Background: Male infertility is responsible for 35% of infertile couples. Aim: To investigate the causes of male infertility and the relative importance of endocrine factors. Patients and methods: Patients referred to an andrology clinic due to an abnormal spermiogram were studied. A testitular examination, spermiogram and determination of FSH, LH, testosterone and prolactin were done to all. Testicular biopsy was done to patients with severe oligospermia or azoospermia. Causes of infertility were defined and classified as pretesticular, testicular, posttesticular or unclassified. Results: Two hundred fifty seven males were studied. In 3.5% of them, the cause of infertility was defined as pretesticular (that included hypothalamic and pituitary endocrine causes), in 66.9% it was classified as testicular, in 15.6% as posttesticular and in 14%, as unclassified. Thirty percent of infertility cases were idiopathic, 17.9% were associated to varicocele, 12.8% were associated to cryptorchidism, 8.9% to Klinefelter syndrome and 6.6% to exposure to toxic substances. In 50% of patients with cryptorchidism, this abnormality was found during the specialized andrological examination and referrals for surgical correction were made late. Two thirds of patients with Klinefelter syndrome were hypoandrogenic. Conclusions: Causes for male infertility should be investigated and diagnosed accurately. Primary hypoandrogenic testicular failures must be treated with hormone replacement therapy
author	Devoto C,Enzo Madariaga A,Marcia Lioi C,Ximena
author_facet	Devoto C,Enzo Madariaga A,Marcia Lioi C,Ximena
author_sort	Devoto C,Enzo
title	Factores causales de infertilidad masculina: Contribución del factor endocrino
title_short	Factores causales de infertilidad masculina: Contribución del factor endocrino
title_full	Factores causales de infertilidad masculina: Contribución del factor endocrino
title_fullStr	Factores causales de infertilidad masculina: Contribución del factor endocrino
title_full_unstemmed	Factores causales de infertilidad masculina: Contribución del factor endocrino
title_sort	factores causales de infertilidad masculina: contribución del factor endocrino
publisher	Sociedad Médica de Santiago
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000200008
work_keys_str_mv	AT devotocenzo factorescausalesdeinfertilidadmasculinacontribuciondelfactorendocrino AT madariagaamarcia factorescausalesdeinfertilidadmasculinacontribuciondelfactorendocrino AT lioicximena factorescausalesdeinfertilidadmasculinacontribuciondelfactorendocrino
_version_	1718435904616398848

Factores causales de infertilidad masculina: Contribución del factor endocrino

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