Malformaciones congénitas y exposición a pesticidas

Background: Chronic pesticide exposure is a recognized risk for human health. The frequency of congenital malformations in exposed people, can be used for epidemiological studies assessing reproductive risk secondary to toxic exposure. Aim: To study the association between the incidence of congenita...

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Autores principales:	Rojas R,Alejandra, Ojeda B,María Elena, Barraza O,Ximena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2000
Materias:	Abnormalities Abnormalities, drug induced Pesticides Pesticide residues
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000400006
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spelling	oai:scielo:S0034-988720000004000062005-11-29Malformaciones congénitas y exposición a pesticidasRojas R,AlejandraOjeda B,María ElenaBarraza O,Ximena Abnormalities Abnormalities, drug induced Pesticides Pesticide residues Background: Chronic pesticide exposure is a recognized risk for human health. The frequency of congenital malformations in exposed people, can be used for epidemiological studies assessing reproductive risk secondary to toxic exposure. Aim: To study the association between the incidence of congenital malformations and parents exposure to pesticides. Material and methods: A prospective study of cases and controls. The exposure could be caused by occupational activities or residence around fumigated crops. The records of cases and controls from the surveillance carried out in the Hospital Regional de Rancagua were analyzed. This hospital is active member of a collaborative study of congenital malformations in Latin America. Results: In two years there was a total of 453 newborns (18 stillborn) with congenital malformations, with an incidence of 41.24 . Considering only children born alive, the paired analysis of cases and controls showed an association of congenital malformations with a history of maternal exposure, with an attributable fraction of 54.4%. Conclusions: These results, showing an association between pesticide exposure and congenital malformations, should be analyzed in the future by a logistic regression test. (Rev Méd Chile 2000; 128: 399-404)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.4 20002000-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000400006es10.4067/S0034-98872000000400006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Abnormalities Abnormalities, drug induced Pesticides Pesticide residues
spellingShingle	Abnormalities Abnormalities, drug induced Pesticides Pesticide residues Rojas R,Alejandra Ojeda B,María Elena Barraza O,Ximena Malformaciones congénitas y exposición a pesticidas
description	Background: Chronic pesticide exposure is a recognized risk for human health. The frequency of congenital malformations in exposed people, can be used for epidemiological studies assessing reproductive risk secondary to toxic exposure. Aim: To study the association between the incidence of congenital malformations and parents exposure to pesticides. Material and methods: A prospective study of cases and controls. The exposure could be caused by occupational activities or residence around fumigated crops. The records of cases and controls from the surveillance carried out in the Hospital Regional de Rancagua were analyzed. This hospital is active member of a collaborative study of congenital malformations in Latin America. Results: In two years there was a total of 453 newborns (18 stillborn) with congenital malformations, with an incidence of 41.24 . Considering only children born alive, the paired analysis of cases and controls showed an association of congenital malformations with a history of maternal exposure, with an attributable fraction of 54.4%. Conclusions: These results, showing an association between pesticide exposure and congenital malformations, should be analyzed in the future by a logistic regression test. (Rev Méd Chile 2000; 128: 399-404)
author	Rojas R,Alejandra Ojeda B,María Elena Barraza O,Ximena
author_facet	Rojas R,Alejandra Ojeda B,María Elena Barraza O,Ximena
author_sort	Rojas R,Alejandra
title	Malformaciones congénitas y exposición a pesticidas
title_short	Malformaciones congénitas y exposición a pesticidas
title_full	Malformaciones congénitas y exposición a pesticidas
title_fullStr	Malformaciones congénitas y exposición a pesticidas
title_full_unstemmed	Malformaciones congénitas y exposición a pesticidas
title_sort	malformaciones congénitas y exposición a pesticidas
publisher	Sociedad Médica de Santiago
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000400006
work_keys_str_mv	AT rojasralejandra malformacionescongenitasyexposicionapesticidas AT ojedabmariaelena malformacionescongenitasyexposicionapesticidas AT barrazaoximena malformacionescongenitasyexposicionapesticidas
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Malformaciones congénitas y exposición a pesticidas

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