La inmunología clínica actual: una perspectiva genética y molecular

During the last few decades, basic scientists and clinicians have gained a deeper insight of the cellular and molecular physiology of the immune system. The widespread application of molecular biology and genetic techniques has advanced our understanding of states of health and disease, bringing for...

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Autores principales:	Carrión A,Flavio, E Figueroa,Fernando, Rodríguez G,Cristián
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2000
Materias:	Molecular Biology Immunologic techniques Immunological diseases Autoimmunity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000600013
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spelling	oai:scielo:S0034-988720000006000132005-11-14La inmunología clínica actual: una perspectiva genética y molecularCarrión A,FlavioE Figueroa,FernandoRodríguez G,Cristián Molecular Biology Immunologic techniques Immunological diseases Autoimmunity During the last few decades, basic scientists and clinicians have gained a deeper insight of the cellular and molecular physiology of the immune system. The widespread application of molecular biology and genetic techniques has advanced our understanding of states of health and disease, bringing forth renewed hopes concerning the advent of a more "specific" therapeutic era of clinical immunology. The precise structural and genetic characterization of molecular complexes such as B and T-cell receptors, the Major Histocompatibility Complex (MHC), cytokines, chemokines, cellular receptors and co-receptors has produced a wealth of information open to both diagnostic and therapeutic purposes. We herein review several recent advances in the molecular and genetic characterization of immune deficiency states, autoimmunity and the induction of antigen specific immune unresponsiveness or tolerance, together with the therapeutic implications of these findings. (Rev Méd Chile 2000; 128: 650-8).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.6 20002000-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000600013es10.4067/S0034-98872000000600013
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Molecular Biology Immunologic techniques Immunological diseases Autoimmunity
spellingShingle	Molecular Biology Immunologic techniques Immunological diseases Autoimmunity Carrión A,Flavio E Figueroa,Fernando Rodríguez G,Cristián La inmunología clínica actual: una perspectiva genética y molecular
description	During the last few decades, basic scientists and clinicians have gained a deeper insight of the cellular and molecular physiology of the immune system. The widespread application of molecular biology and genetic techniques has advanced our understanding of states of health and disease, bringing forth renewed hopes concerning the advent of a more "specific" therapeutic era of clinical immunology. The precise structural and genetic characterization of molecular complexes such as B and T-cell receptors, the Major Histocompatibility Complex (MHC), cytokines, chemokines, cellular receptors and co-receptors has produced a wealth of information open to both diagnostic and therapeutic purposes. We herein review several recent advances in the molecular and genetic characterization of immune deficiency states, autoimmunity and the induction of antigen specific immune unresponsiveness or tolerance, together with the therapeutic implications of these findings. (Rev Méd Chile 2000; 128: 650-8).
author	Carrión A,Flavio E Figueroa,Fernando Rodríguez G,Cristián
author_facet	Carrión A,Flavio E Figueroa,Fernando Rodríguez G,Cristián
author_sort	Carrión A,Flavio
title	La inmunología clínica actual: una perspectiva genética y molecular
title_short	La inmunología clínica actual: una perspectiva genética y molecular
title_full	La inmunología clínica actual: una perspectiva genética y molecular
title_fullStr	La inmunología clínica actual: una perspectiva genética y molecular
title_full_unstemmed	La inmunología clínica actual: una perspectiva genética y molecular
title_sort	la inmunología clínica actual: una perspectiva genética y molecular
publisher	Sociedad Médica de Santiago
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000600013
work_keys_str_mv	AT carrionaflavio lainmunologiaclinicaactualunaperspectivageneticaymolecular AT efigueroafernando lainmunologiaclinicaactualunaperspectivageneticaymolecular AT rodriguezgcristian lainmunologiaclinicaactualunaperspectivageneticaymolecular
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La inmunología clínica actual: una perspectiva genética y molecular

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