Serum lipids in newborns with intrauterine growth retardation

Background: The X syndrome, related to coronary disease in adults, could be possibly programmed priory to delivery, in children with intrauterine growth retardation. Aim: To measure serum lipids in newborns with symmetrical or asymmetrical intrauterine growth retardation. Patients and methods: One h...

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Autores principales: Molina S,Marta, Casanueva E,Víctor, Ferrada N,María Cristina, Pérez V,Ruth, Dios T,Gabriela, Reyes R,Marina, Venegas B,Héctor, Cid S,Luis
Lenguaje:English
Publicado: Sociedad Médica de Santiago 2000
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000700006
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spelling oai:scielo:S0034-988720000007000062000-09-01Serum lipids in newborns with intrauterine growth retardationMolina S,MartaCasanueva E,VíctorFerrada N,María CristinaPérez V,RuthDios T,GabrielaReyes R,MarinaVenegas B,HéctorCid S,Luis Child development Fetal growth retardation Syndrome X Background: The X syndrome, related to coronary disease in adults, could be possibly programmed priory to delivery, in children with intrauterine growth retardation. Aim: To measure serum lipids in newborns with symmetrical or asymmetrical intrauterine growth retardation. Patients and methods: One hundred thirty five newborns with intrauterine growth retardation and 116 normal term newborns, with 38 to 41 gestational weeks, were studied. Total, HDL, and LDL cholesterol, triglycerides and apoproteins. A1 and B were measured in imbilical cord blood samples. Results: No differences in total, HDL, LDL cholesterol, apoproteins A1 and B were observed between the study groups. Triglycerides were higher in newborns with intrauterine growth retardation, compared to normal term newborns (45 ± 27 and 36 ± 19 mg/dl respectively, p<0,001). Differences in serum triglyceride levels respect to controls were observed in both male and female newborns with asymmetrical growth retardation. Likewise the differences respect to controls were observed in newborns with mild or severe but not with moderate growth retardation. Conclusions: Newborns with intrauterine growth retardation have higher triglyceride levels than normal term newborns. (Rev Méd Chile 2000; 128: 741-8).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.7 20002000-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000700006en10.4067/S0034-98872000000700006
institution Scielo Chile
collection Scielo Chile
language English
topic Child development
Fetal growth retardation
Syndrome X
spellingShingle Child development
Fetal growth retardation
Syndrome X
Molina S,Marta
Casanueva E,Víctor
Ferrada N,María Cristina
Pérez V,Ruth
Dios T,Gabriela
Reyes R,Marina
Venegas B,Héctor
Cid S,Luis
Serum lipids in newborns with intrauterine growth retardation
description Background: The X syndrome, related to coronary disease in adults, could be possibly programmed priory to delivery, in children with intrauterine growth retardation. Aim: To measure serum lipids in newborns with symmetrical or asymmetrical intrauterine growth retardation. Patients and methods: One hundred thirty five newborns with intrauterine growth retardation and 116 normal term newborns, with 38 to 41 gestational weeks, were studied. Total, HDL, and LDL cholesterol, triglycerides and apoproteins. A1 and B were measured in imbilical cord blood samples. Results: No differences in total, HDL, LDL cholesterol, apoproteins A1 and B were observed between the study groups. Triglycerides were higher in newborns with intrauterine growth retardation, compared to normal term newborns (45 ± 27 and 36 ± 19 mg/dl respectively, p<0,001). Differences in serum triglyceride levels respect to controls were observed in both male and female newborns with asymmetrical growth retardation. Likewise the differences respect to controls were observed in newborns with mild or severe but not with moderate growth retardation. Conclusions: Newborns with intrauterine growth retardation have higher triglyceride levels than normal term newborns. (Rev Méd Chile 2000; 128: 741-8).
author Molina S,Marta
Casanueva E,Víctor
Ferrada N,María Cristina
Pérez V,Ruth
Dios T,Gabriela
Reyes R,Marina
Venegas B,Héctor
Cid S,Luis
author_facet Molina S,Marta
Casanueva E,Víctor
Ferrada N,María Cristina
Pérez V,Ruth
Dios T,Gabriela
Reyes R,Marina
Venegas B,Héctor
Cid S,Luis
author_sort Molina S,Marta
title Serum lipids in newborns with intrauterine growth retardation
title_short Serum lipids in newborns with intrauterine growth retardation
title_full Serum lipids in newborns with intrauterine growth retardation
title_fullStr Serum lipids in newborns with intrauterine growth retardation
title_full_unstemmed Serum lipids in newborns with intrauterine growth retardation
title_sort serum lipids in newborns with intrauterine growth retardation
publisher Sociedad Médica de Santiago
publishDate 2000
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000700006
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