Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas

Background: AgNOR technique detects, using silver salts, argyrophylic proteins of the nucleolar organizer region (NOR). The number and size of NOR reflect cell activity, proliferation and transformation and may help to differentiate benign from malignant cells. Aim: To assess the value of AgNOR assa...

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Autores principales:	Rocher,Adriana E, Blanco,Ana María, Palaoro,Luis A
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2000
Materias:	Cytodiagnosis Cytological techniques Neoplasm metastasis Serous membrane
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000900002
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spelling	oai:scielo:S0034-988720000009000022005-11-15Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosasRocher,Adriana EBlanco,Ana MaríaPalaoro,Luis A Cytodiagnosis Cytological techniques Neoplasm metastasis Serous membrane Background: AgNOR technique detects, using silver salts, argyrophylic proteins of the nucleolar organizer region (NOR). The number and size of NOR reflect cell activity, proliferation and transformation and may help to differentiate benign from malignant cells. Aim: To assess the value of AgNOR assay to differentiate reactive mesothelial cells from malignant cells in serous effusions. Material and methods: Thirty one fluids obtained from 16 pleural, 14 peritoneal and one pericardial effusion, were studied. The fluids were processed with Giemsa and Papanicolau stains and with the AgNOR technique. The number of AgNOR dots were counted (only when it was possible to distinguish each individual dot) and the mean value per nucleus was calculated for each smear. Results: Mesothelial cells had a mean of 4,88 ± 1,5 dots compared with 13,78 ± 3,88 dots in the malignant cells (p<0,001). Conclusions: AgNOR assay can be useful for the differentiation of benign and malignant cells in serous effusions. (Rev Méd Chile 2000; 128: 963-8)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.9 20002000-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000900002es10.4067/S0034-98872000000900002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cytodiagnosis Cytological techniques Neoplasm metastasis Serous membrane
spellingShingle	Cytodiagnosis Cytological techniques Neoplasm metastasis Serous membrane Rocher,Adriana E Blanco,Ana María Palaoro,Luis A Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas
description	Background: AgNOR technique detects, using silver salts, argyrophylic proteins of the nucleolar organizer region (NOR). The number and size of NOR reflect cell activity, proliferation and transformation and may help to differentiate benign from malignant cells. Aim: To assess the value of AgNOR assay to differentiate reactive mesothelial cells from malignant cells in serous effusions. Material and methods: Thirty one fluids obtained from 16 pleural, 14 peritoneal and one pericardial effusion, were studied. The fluids were processed with Giemsa and Papanicolau stains and with the AgNOR technique. The number of AgNOR dots were counted (only when it was possible to distinguish each individual dot) and the mean value per nucleus was calculated for each smear. Results: Mesothelial cells had a mean of 4,88 ± 1,5 dots compared with 13,78 ± 3,88 dots in the malignant cells (p<0,001). Conclusions: AgNOR assay can be useful for the differentiation of benign and malignant cells in serous effusions. (Rev Méd Chile 2000; 128: 963-8)
author	Rocher,Adriana E Blanco,Ana María Palaoro,Luis A
author_facet	Rocher,Adriana E Blanco,Ana María Palaoro,Luis A
author_sort	Rocher,Adriana E
title	Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas
title_short	Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas
title_full	Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas
title_fullStr	Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas
title_full_unstemmed	Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas
title_sort	utilidad de la técnica de agnor en la interpretación de los derrames de cavidades serosas
publisher	Sociedad Médica de Santiago
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000900002
work_keys_str_mv	AT rocheradrianae utilidaddelatecnicadeagnorenlainterpretaciondelosderramesdecavidadesserosas AT blancoanamaria utilidaddelatecnicadeagnorenlainterpretaciondelosderramesdecavidadesserosas AT palaoroluisa utilidaddelatecnicadeagnorenlainterpretaciondelosderramesdecavidadesserosas
_version_	1718435934223990784

Utilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas

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