Células natural killer y el sistema inmune innato en la patología infecciosa
Natural killer (NK) cells form a unique third group of lymphocytes that differs from T and B cells in surface phenotype, target cell recognition and function. NK cells have two relevant functions, related to the innate immune response against pathogens microorganisms. One is cytotoxicity, mediated b...
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| Lenguaje: | Spanish / Castilian |
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Sociedad Médica de Santiago
2000
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| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000001200009 |
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oai:scielo:S0034-988720000012000092001-02-08Células natural killer y el sistema inmune innato en la patología infecciosaSepúlveda C,CeciliaPuente P,Javier Cytokines Killer cells Lymphocytes Natural killer (NK) cells form a unique third group of lymphocytes that differs from T and B cells in surface phenotype, target cell recognition and function. NK cells have two relevant functions, related to the innate immune response against pathogens microorganisms. One is cytotoxicity, mediated by the recognition and lysis of target cells such as virus and bacteria infected-cells. The second NK cell function is to produce cytokines, mainly IFN-g, that can modulate innate and specific immune responses. Cytotoxicity and cytokine secretion contribute to host resistance against microorganisms and both functions are significantly altered in infectious diseases (Rev Méd Chile 2000; 128: 1361-70).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.12 20002000-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000001200009es10.4067/S0034-98872000001200009 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Cytokines Killer cells Lymphocytes |
| spellingShingle |
Cytokines Killer cells Lymphocytes Sepúlveda C,Cecilia Puente P,Javier Células natural killer y el sistema inmune innato en la patología infecciosa |
| description |
Natural killer (NK) cells form a unique third group of lymphocytes that differs from T and B cells in surface phenotype, target cell recognition and function. NK cells have two relevant functions, related to the innate immune response against pathogens microorganisms. One is cytotoxicity, mediated by the recognition and lysis of target cells such as virus and bacteria infected-cells. The second NK cell function is to produce cytokines, mainly IFN-g, that can modulate innate and specific immune responses. Cytotoxicity and cytokine secretion contribute to host resistance against microorganisms and both functions are significantly altered in infectious diseases (Rev Méd Chile 2000; 128: 1361-70). |
| author |
Sepúlveda C,Cecilia Puente P,Javier |
| author_facet |
Sepúlveda C,Cecilia Puente P,Javier |
| author_sort |
Sepúlveda C,Cecilia |
| title |
Células natural killer y el sistema inmune innato en la patología infecciosa |
| title_short |
Células natural killer y el sistema inmune innato en la patología infecciosa |
| title_full |
Células natural killer y el sistema inmune innato en la patología infecciosa |
| title_fullStr |
Células natural killer y el sistema inmune innato en la patología infecciosa |
| title_full_unstemmed |
Células natural killer y el sistema inmune innato en la patología infecciosa |
| title_sort |
células natural killer y el sistema inmune innato en la patología infecciosa |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2000 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000001200009 |
| work_keys_str_mv |
AT sepulvedaccecilia celulasnaturalkilleryelsistemainmuneinnatoenlapatologiainfecciosa AT puentepjavier celulasnaturalkilleryelsistemainmuneinnatoenlapatologiainfecciosa |
| _version_ |
1718435949138935808 |