Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón
Background: Heart transplantation currently provides the most effective treatment for advanced heart failure. However, medical therapy for this condition has also improved, heart donors are scarce and the cost of the procedure is high. Therefore the indications and management of these patients need...
Guardado en:
Autores principales: | , , , , , , , , , , , , |
---|---|
Lenguaje: | Spanish / Castilian |
Publicado: |
Sociedad Médica de Santiago
2001
|
Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100002 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:scielo:S0034-98872001000100002 |
---|---|
record_format |
dspace |
spelling |
oai:scielo:S0034-988720010001000022005-11-23Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazónMorán V,SergioCastro G,PabloZalaquett S,RicardoBecker R,PedroGarayar P,BernarditaIrarrázaval Ll,Manuel JoséJalil M,orgeLema F,GuillermoFajuri N,AlejandroPérez P,OsvaldoMartínez S,AlejandroMarchant D,EugenioChamorro S,Gastón Heart failure congestive Heart transplantation Surgical procedures, operative Background: Heart transplantation currently provides the most effective treatment for advanced heart failure. However, medical therapy for this condition has also improved, heart donors are scarce and the cost of the procedure is high. Therefore the indications and management of these patients need reevaluation. Aim: To analyze the results of 24 patients submitted to heart transplantation for end-stage heart failure needing repeated hospitalizations and i.v. inotropes for compensation. Patients and methods: The group was comprised by 21 men and 3 women with a mean age of 36.8 years, mean left ventricular ejection fraction 19±4.5%, mean systolic pulmonary artery pressure 48±13 mmHg (24-70) and mean pulmonary vascular resistance 2.6 Wood Units (1-5). Fourteen patients (58%) had a previous median sternotomy. Immunosupression did not include induction therapy and steroids were discontinued early. Results: Operative mortality was 4% at 30 days. Actuarial survival at one year was 90% and at 5 years 72%. Freedom from rejection at one year was 76% and at 5 years 50%. Freedom from infection was 70% at one year and 56.5% at five years. All patients with more than 3 months of follow-up were in functional class I. Conclusions: These results justify the proposed modifications for transplantation protocols (Rev Méd Chile 2001; 129: 9-17).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.1 20012001-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100002es10.4067/S0034-98872001000100002 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Heart failure congestive Heart transplantation Surgical procedures, operative |
spellingShingle |
Heart failure congestive Heart transplantation Surgical procedures, operative Morán V,Sergio Castro G,Pablo Zalaquett S,Ricardo Becker R,Pedro Garayar P,Bernardita Irarrázaval Ll,Manuel José Jalil M,orge Lema F,Guillermo Fajuri N,Alejandro Pérez P,Osvaldo Martínez S,Alejandro Marchant D,Eugenio Chamorro S,Gastón Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón |
description |
Background: Heart transplantation currently provides the most effective treatment for advanced heart failure. However, medical therapy for this condition has also improved, heart donors are scarce and the cost of the procedure is high. Therefore the indications and management of these patients need reevaluation. Aim: To analyze the results of 24 patients submitted to heart transplantation for end-stage heart failure needing repeated hospitalizations and i.v. inotropes for compensation. Patients and methods: The group was comprised by 21 men and 3 women with a mean age of 36.8 years, mean left ventricular ejection fraction 19±4.5%, mean systolic pulmonary artery pressure 48±13 mmHg (24-70) and mean pulmonary vascular resistance 2.6 Wood Units (1-5). Fourteen patients (58%) had a previous median sternotomy. Immunosupression did not include induction therapy and steroids were discontinued early. Results: Operative mortality was 4% at 30 days. Actuarial survival at one year was 90% and at 5 years 72%. Freedom from rejection at one year was 76% and at 5 years 50%. Freedom from infection was 70% at one year and 56.5% at five years. All patients with more than 3 months of follow-up were in functional class I. Conclusions: These results justify the proposed modifications for transplantation protocols (Rev Méd Chile 2001; 129: 9-17). |
author |
Morán V,Sergio Castro G,Pablo Zalaquett S,Ricardo Becker R,Pedro Garayar P,Bernardita Irarrázaval Ll,Manuel José Jalil M,orge Lema F,Guillermo Fajuri N,Alejandro Pérez P,Osvaldo Martínez S,Alejandro Marchant D,Eugenio Chamorro S,Gastón |
author_facet |
Morán V,Sergio Castro G,Pablo Zalaquett S,Ricardo Becker R,Pedro Garayar P,Bernardita Irarrázaval Ll,Manuel José Jalil M,orge Lema F,Guillermo Fajuri N,Alejandro Pérez P,Osvaldo Martínez S,Alejandro Marchant D,Eugenio Chamorro S,Gastón |
author_sort |
Morán V,Sergio |
title |
Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón |
title_short |
Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón |
title_full |
Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón |
title_fullStr |
Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón |
title_full_unstemmed |
Tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón |
title_sort |
tratamiento de la insuficiencia cardíaca avanzada mediante trasplante de corazón |
publisher |
Sociedad Médica de Santiago |
publishDate |
2001 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100002 |
work_keys_str_mv |
AT moranvsergio tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT castrogpablo tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT zalaquettsricardo tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT beckerrpedro tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT garayarpbernardita tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT irarrazavalllmanueljose tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT jalilmorge tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT lemafguillermo tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT fajurinalejandro tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT perezposvaldo tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT martinezsalejandro tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT marchantdeugenio tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon AT chamorrosgaston tratamientodelainsuficienciacardiacaavanzadamediantetrasplantedecorazon |
_version_ |
1718435950900543488 |