Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos

Background: Little information is available in Chile about hepatitis C virus (HCV) in hematological and oncohematological patients. Aim: To evaluate the prevalence of hepatitis C virus markers in a group of hematological and oncohematological pediatric patients seen at Valdivia Regional Hospital. Pa...

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Autores principales:	Vega R,Inés, León R,Alvaro, Zolezzi R,Paolina, Ibarra V,Humberto, Faúndez V,Cecilia, Montecinos V,Jorge
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Hematologic diseases Hepatitis C Hepatitis C antibodies Polymerase chain reaction
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100003
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spelling	oai:scielo:S0034-988720010001000032005-11-23Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicosVega R,InésLeón R,AlvaroZolezzi R,PaolinaIbarra V,HumbertoFaúndez V,CeciliaMontecinos V,Jorge Hematologic diseases Hepatitis C Hepatitis C antibodies Polymerase chain reaction Background: Little information is available in Chile about hepatitis C virus (HCV) in hematological and oncohematological patients. Aim: To evaluate the prevalence of hepatitis C virus markers in a group of hematological and oncohematological pediatric patients seen at Valdivia Regional Hospital. Patients and methods: Antibodies against virus C, determined by ELISA and viral RNA, determined using RT-polymerase chain reaction, were measured in 54 blood samples from children with hematological diseases (34 with Acute Lymphoblastic Leukaemia, 4 with Hodgkin Diseases, 4 with Haemolytic Anemia, 5 with Sarcomas, 2 with Non-Hodgkin Lymphoma, 2 with Thrombocytopenic Purpura, 1 with an Ependimoma, one with a Wilms Tumor and 1 with a Von Willebrand Disease). Results: All samples were negative for antibodies against hepatitis C virus. Viral RNA was found in four children, all with a diagnosis of acute lymphoblastic leukemia and who received chemotherapy and multiple transfusions. Conclusions: The prevalence of Viral RNA for hepatitis C virus in oncohematological patients in our study is high and associated with the use of chemotherapy and multiple transfusions (Rev Méd Chile 2001; 129: 18-22)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.1 20012001-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100003es10.4067/S0034-98872001000100003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hematologic diseases Hepatitis C Hepatitis C antibodies Polymerase chain reaction
spellingShingle	Hematologic diseases Hepatitis C Hepatitis C antibodies Polymerase chain reaction Vega R,Inés León R,Alvaro Zolezzi R,Paolina Ibarra V,Humberto Faúndez V,Cecilia Montecinos V,Jorge Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos
description	Background: Little information is available in Chile about hepatitis C virus (HCV) in hematological and oncohematological patients. Aim: To evaluate the prevalence of hepatitis C virus markers in a group of hematological and oncohematological pediatric patients seen at Valdivia Regional Hospital. Patients and methods: Antibodies against virus C, determined by ELISA and viral RNA, determined using RT-polymerase chain reaction, were measured in 54 blood samples from children with hematological diseases (34 with Acute Lymphoblastic Leukaemia, 4 with Hodgkin Diseases, 4 with Haemolytic Anemia, 5 with Sarcomas, 2 with Non-Hodgkin Lymphoma, 2 with Thrombocytopenic Purpura, 1 with an Ependimoma, one with a Wilms Tumor and 1 with a Von Willebrand Disease). Results: All samples were negative for antibodies against hepatitis C virus. Viral RNA was found in four children, all with a diagnosis of acute lymphoblastic leukemia and who received chemotherapy and multiple transfusions. Conclusions: The prevalence of Viral RNA for hepatitis C virus in oncohematological patients in our study is high and associated with the use of chemotherapy and multiple transfusions (Rev Méd Chile 2001; 129: 18-22)
author	Vega R,Inés León R,Alvaro Zolezzi R,Paolina Ibarra V,Humberto Faúndez V,Cecilia Montecinos V,Jorge
author_facet	Vega R,Inés León R,Alvaro Zolezzi R,Paolina Ibarra V,Humberto Faúndez V,Cecilia Montecinos V,Jorge
author_sort	Vega R,Inés
title	Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos
title_short	Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos
title_full	Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos
title_fullStr	Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos
title_full_unstemmed	Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos
title_sort	virus de la hepatitis c en un grupo de pacientes hematológicos y oncohematológicos
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100003
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Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos

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