Estudio de tres loci hipervariables en población mixta chilena

Background: Genetic markers are useful to study evolution parameters in populations and to determine kinship. Aim: To characterize three short tandem repeat loci in a sample of Chilean subjects and compare them with Caucasian and Hispanic populations. Material and methods: Three hundred ninety three...

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Autores principales:	Novoa C,M del Rosario, Labbé C,Carolina, Jorquera G,Hugo, Moreno Ch,Fabián, Aguirre M,M Eugenia, Cifuentes O,Lucía
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Gene identity Genetic markers Genetic screening
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100010
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id	oai:scielo:S0034-98872001000100010
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spelling	oai:scielo:S0034-988720010001000102005-11-23Estudio de tres loci hipervariables en población mixta chilenaNovoa C,M del RosarioLabbé C,CarolinaJorquera G,HugoMoreno Ch,FabiánAguirre M,M EugeniaCifuentes O,Lucía Gene identity Genetic markers Genetic screening Background: Genetic markers are useful to study evolution parameters in populations and to determine kinship. Aim: To characterize three short tandem repeat loci in a sample of Chilean subjects and compare them with Caucasian and Hispanic populations. Material and methods: Three hundred ninety three unrelated subjects that were sent for genetic studies from courts of justice, were studied. The loci FESFPS, F13A01 and vWA in blood samples, were typified amplifying DNA by polymerase chain reactions. Results: The three studied loci were highly polymorphic. F13A01 and FESFPS were in Hardy-Weinberg genetic equilibrium. A significant excess of heterozygotes was detected for vWA locus. There were no differences in allele frequencies, according to ethnic origins of last names. Allele frequencies for F13A01 and vWA loci were similar to those of Hispanic populations of Unites States and FESFPS loci was different. Conclusions: All three loci had a high efficiency for genetic identification tests according to the estimated a priory exclusion probability (Rev Méd Chile 2001; 129: 75-79)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.1 20012001-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100010es10.4067/S0034-98872001000100010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Gene identity Genetic markers Genetic screening
spellingShingle	Gene identity Genetic markers Genetic screening Novoa C,M del Rosario Labbé C,Carolina Jorquera G,Hugo Moreno Ch,Fabián Aguirre M,M Eugenia Cifuentes O,Lucía Estudio de tres loci hipervariables en población mixta chilena
description	Background: Genetic markers are useful to study evolution parameters in populations and to determine kinship. Aim: To characterize three short tandem repeat loci in a sample of Chilean subjects and compare them with Caucasian and Hispanic populations. Material and methods: Three hundred ninety three unrelated subjects that were sent for genetic studies from courts of justice, were studied. The loci FESFPS, F13A01 and vWA in blood samples, were typified amplifying DNA by polymerase chain reactions. Results: The three studied loci were highly polymorphic. F13A01 and FESFPS were in Hardy-Weinberg genetic equilibrium. A significant excess of heterozygotes was detected for vWA locus. There were no differences in allele frequencies, according to ethnic origins of last names. Allele frequencies for F13A01 and vWA loci were similar to those of Hispanic populations of Unites States and FESFPS loci was different. Conclusions: All three loci had a high efficiency for genetic identification tests according to the estimated a priory exclusion probability (Rev Méd Chile 2001; 129: 75-79)
author	Novoa C,M del Rosario Labbé C,Carolina Jorquera G,Hugo Moreno Ch,Fabián Aguirre M,M Eugenia Cifuentes O,Lucía
author_facet	Novoa C,M del Rosario Labbé C,Carolina Jorquera G,Hugo Moreno Ch,Fabián Aguirre M,M Eugenia Cifuentes O,Lucía
author_sort	Novoa C,M del Rosario
title	Estudio de tres loci hipervariables en población mixta chilena
title_short	Estudio de tres loci hipervariables en población mixta chilena
title_full	Estudio de tres loci hipervariables en población mixta chilena
title_fullStr	Estudio de tres loci hipervariables en población mixta chilena
title_full_unstemmed	Estudio de tres loci hipervariables en población mixta chilena
title_sort	estudio de tres loci hipervariables en población mixta chilena
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000100010
work_keys_str_mv	AT novoacmdelrosario estudiodetreslocihipervariablesenpoblacionmixtachilena AT labbeccarolina estudiodetreslocihipervariablesenpoblacionmixtachilena AT jorqueraghugo estudiodetreslocihipervariablesenpoblacionmixtachilena AT morenochfabian estudiodetreslocihipervariablesenpoblacionmixtachilena AT aguirremmeugenia estudiodetreslocihipervariablesenpoblacionmixtachilena AT cifuentesolucia estudiodetreslocihipervariablesenpoblacionmixtachilena
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Estudio de tres loci hipervariables en población mixta chilena

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