Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana

Background: Serum leptin levels increase during pregnancy and this increase is more pronounced in women with preemclapsia. Aim: To determine if there is a significant correlation of serum leptin with insulin and glucose levels in normotensive pregnant women and in preeclampsia patients. Material and...

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Autores principales:	Martínez-Abundis,Esperanza, González-Ortiz,Manuel
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Insulin Leptin Preeclampsia Pregnancy complications
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000200004
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spelling	oai:scielo:S0034-988720010002000042001-04-09Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicanaMartínez-Abundis,EsperanzaGonzález-Ortiz,Manuel Insulin Leptin Preeclampsia Pregnancy complications Background: Serum leptin levels increase during pregnancy and this increase is more pronounced in women with preemclapsia. Aim: To determine if there is a significant correlation of serum leptin with insulin and glucose levels in normotensive pregnant women and in preeclampsia patients. Material and methods: A nested case-control study in 16 normotensive pregnant women and in 16 preeclampsia mestizo Mexicans in the third trimester of the gestation, matched by age, gestational age and pre gestational body mass index. Venous blood samples after at least 6 h fast, were obtained and stored at -70 °C to measure serum leptin levels by ELISA, insulin concentrations by RIA and glucose by the glucose oxidase technique. Results: There were no differences between normotensive women and those with preeclampsia in serum leptin, insulin and glucose levels. There was a positive correlation between leptin and insulin concentrations (p=0.005), a negative correlation between leptin and glucose levels (p=0.02) and no correlation between leptin and pre gestational body mass index. Conclusions: In this study, women with preeclampsia did not have higher leptin levels than normotensive pregnant women (Rev Méd Chile 2001; 129: 149-54).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.2 20012001-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000200004es10.4067/S0034-98872001000200004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Insulin Leptin Preeclampsia Pregnancy complications
spellingShingle	Insulin Leptin Preeclampsia Pregnancy complications Martínez-Abundis,Esperanza González-Ortiz,Manuel Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana
description	Background: Serum leptin levels increase during pregnancy and this increase is more pronounced in women with preemclapsia. Aim: To determine if there is a significant correlation of serum leptin with insulin and glucose levels in normotensive pregnant women and in preeclampsia patients. Material and methods: A nested case-control study in 16 normotensive pregnant women and in 16 preeclampsia mestizo Mexicans in the third trimester of the gestation, matched by age, gestational age and pre gestational body mass index. Venous blood samples after at least 6 h fast, were obtained and stored at -70 °C to measure serum leptin levels by ELISA, insulin concentrations by RIA and glucose by the glucose oxidase technique. Results: There were no differences between normotensive women and those with preeclampsia in serum leptin, insulin and glucose levels. There was a positive correlation between leptin and insulin concentrations (p=0.005), a negative correlation between leptin and glucose levels (p=0.02) and no correlation between leptin and pre gestational body mass index. Conclusions: In this study, women with preeclampsia did not have higher leptin levels than normotensive pregnant women (Rev Méd Chile 2001; 129: 149-54).
author	Martínez-Abundis,Esperanza González-Ortiz,Manuel
author_facet	Martínez-Abundis,Esperanza González-Ortiz,Manuel
author_sort	Martínez-Abundis,Esperanza
title	Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana
title_short	Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana
title_full	Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana
title_fullStr	Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana
title_full_unstemmed	Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana
title_sort	relación leptina-insulina en preeclampsia.: estudio en población mestiza mexicana
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000200004
work_keys_str_mv	AT martinezabundisesperanza relacionleptinainsulinaenpreeclampsiaestudioenpoblacionmestizamexicana AT gonzalezortizmanuel relacionleptinainsulinaenpreeclampsiaestudioenpoblacionmestizamexicana
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Relación leptina-insulina en preeclampsia.: Estudio en población mestiza mexicana

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