Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicos

Background: The restless legs syndrome (RLS) is a movement disorder characterized by an imperative urge to move the legs, associated with paraesthesias, motor restlessness and worsening of symptoms at night with at least partial relief by activity. Its prevalence ranges between 2-15% of general adul...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Miranda C,Marcelo, Araya D,Fernando, Castillo C,José Luis, Durán S,Cristina, González F,Fernando, Arís T,Luis
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2001
Materias:
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000200009
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:scielo:S0034-98872001000200009
record_format dspace
spelling oai:scielo:S0034-988720010002000092001-04-09Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicosMiranda C,MarceloAraya D,FernandoCastillo C,José LuisDurán S,CristinaGonzález F,FernandoArís T,Luis Hemodialysis Restless legs Uremia Background: The restless legs syndrome (RLS) is a movement disorder characterized by an imperative urge to move the legs, associated with paraesthesias, motor restlessness and worsening of symptoms at night with at least partial relief by activity. Its prevalence ranges between 2-15% of general adult population and 20-30% of uremic patients. Aim: To evaluate the frecuency and the clinical features of RLS in a sample of general adult population and in uremic patients, in Chile, correlating it with biochemical parameters. Method: 100 relatives of outpatients and 166 uremic patients undergoing chronic haemodialysis were interviewed assessing the presence and severity of RLS according to current diagnostic criteria. Biochemical parameters assessed were hematocrit, serum ferritin, phosphate, intact parathyroid hormone (iPTH) levels. Results: 13% of the general population sample was affected, 15% of them were severe. Forty three cases were found among uremic patients (25.9%) (p <0.01 vs general population), 60% of them were severe and women were affected with higher frequency (p <0.05) and severity (p <0.01). Four patients presented RLS even during hemodialysis. No correlation was found with biochemical parameters. Most RLS cases had not been diagnosed previously. Conclusions: In our population RLS is common and undetected. It is especially prevalent and severe in uremic patients: we found no evidence that anaemia, iron deficiency or iPTH level play a major pathogenic role. Our findings emphasize the need of greater medical awareness of RLS because available therapy may improve the quality of life (Rev Méd Chile 2001; 129: 179-86).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.2 20012001-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000200009es10.4067/S0034-98872001000200009
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Hemodialysis
Restless legs
Uremia
spellingShingle Hemodialysis
Restless legs
Uremia
Miranda C,Marcelo
Araya D,Fernando
Castillo C,José Luis
Durán S,Cristina
González F,Fernando
Arís T,Luis
Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicos
description Background: The restless legs syndrome (RLS) is a movement disorder characterized by an imperative urge to move the legs, associated with paraesthesias, motor restlessness and worsening of symptoms at night with at least partial relief by activity. Its prevalence ranges between 2-15% of general adult population and 20-30% of uremic patients. Aim: To evaluate the frecuency and the clinical features of RLS in a sample of general adult population and in uremic patients, in Chile, correlating it with biochemical parameters. Method: 100 relatives of outpatients and 166 uremic patients undergoing chronic haemodialysis were interviewed assessing the presence and severity of RLS according to current diagnostic criteria. Biochemical parameters assessed were hematocrit, serum ferritin, phosphate, intact parathyroid hormone (iPTH) levels. Results: 13% of the general population sample was affected, 15% of them were severe. Forty three cases were found among uremic patients (25.9%) (p <0.01 vs general population), 60% of them were severe and women were affected with higher frequency (p <0.05) and severity (p <0.01). Four patients presented RLS even during hemodialysis. No correlation was found with biochemical parameters. Most RLS cases had not been diagnosed previously. Conclusions: In our population RLS is common and undetected. It is especially prevalent and severe in uremic patients: we found no evidence that anaemia, iron deficiency or iPTH level play a major pathogenic role. Our findings emphasize the need of greater medical awareness of RLS because available therapy may improve the quality of life (Rev Méd Chile 2001; 129: 179-86).
author Miranda C,Marcelo
Araya D,Fernando
Castillo C,José Luis
Durán S,Cristina
González F,Fernando
Arís T,Luis
author_facet Miranda C,Marcelo
Araya D,Fernando
Castillo C,José Luis
Durán S,Cristina
González F,Fernando
Arís T,Luis
author_sort Miranda C,Marcelo
title Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicos
title_short Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicos
title_full Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicos
title_fullStr Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicos
title_full_unstemmed Síndrome de piernas inquietas: Estudio clínico en población general adulta y en pacientes urémicos
title_sort síndrome de piernas inquietas: estudio clínico en población general adulta y en pacientes urémicos
publisher Sociedad Médica de Santiago
publishDate 2001
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000200009
work_keys_str_mv AT mirandacmarcelo sindromedepiernasinquietasestudioclinicoenpoblaciongeneraladultayenpacientesuremicos
AT arayadfernando sindromedepiernasinquietasestudioclinicoenpoblaciongeneraladultayenpacientesuremicos
AT castillocjoseluis sindromedepiernasinquietasestudioclinicoenpoblaciongeneraladultayenpacientesuremicos
AT duranscristina sindromedepiernasinquietasestudioclinicoenpoblaciongeneraladultayenpacientesuremicos
AT gonzalezffernando sindromedepiernasinquietasestudioclinicoenpoblaciongeneraladultayenpacientesuremicos
AT aristluis sindromedepiernasinquietasestudioclinicoenpoblaciongeneraladultayenpacientesuremicos
_version_ 1718435957381791744