Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile

Background: Mapuche, Chilean natives, represent approximately 9.8% of Chilean population and in the IX region of the country, they account for 18.4% of population over 15 years old. They preserve some socio-cultural characteristics that make them different to the rest of the population. Aim: To desc...

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Autores principales: Kaliski K,Sonia, Bustos M,Luis, Artigas A,Carmen, Alarcón V,César, Vega V,Miguel Angel, Cárdenas R,Cristián
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2001
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300003
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spelling oai:scielo:S0034-988720010003000032001-05-22Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de ChileKaliski K,SoniaBustos M,LuisArtigas A,CarmenAlarcón V,CésarVega V,Miguel AngelCárdenas R,Cristián Aborigines Rheumatic diseases Arthritis rheumatoid Background: Mapuche, Chilean natives, represent approximately 9.8% of Chilean population and in the IX region of the country, they account for 18.4% of population over 15 years old. They preserve some socio-cultural characteristics that make them different to the rest of the population. Aim: To describe the epidemiological characteristics rheumatoid arthritis among Mapuche natives. Subjects and methods: Retrospective review of patients of Mapuche origin with rheumatoid arthritis, seen at Temuco Hospital between 1980 and 1996. Results: Among 308 cases gathered, only 106 (93 women, aged 55 ± 10 years old) complied with 1987 American College of Rheumatology (ACR) criteria for rheumatoid arthritis. The disease began between 29 and 52 years old in 73% of patients and the mean delay in diagnosis was 4.4 years. At diagnosis, 99% had symmetric poliarthritis, 28.3% had either fatigue, fever or weight loss, and 46.9% were in class III or in class IV of ACR-1991. Fifty three percent of patients developed Sicca syndrome, 36% developed nodules, 23% developed Raynaud phenomenon, 11% developed pulmonary involvement, 7% developed vasculitis, 5% developed neurological manifestations and 19% developed ophthalmologic involvement. Rheumatoid factor was positive in 78% and 73% had erosions. HLA DR4 was (+) in 60% of 30 patients. Thirty percent required 3 or more disease modifying drugs and prednisone over 10 mg/day. There was no correlation between functional capacity and several other features of the disease. Conclusions: Mapuche rheumatoid arthritis patients are detected late and have a poor functional capacity at the time of diagnosis. They also have a higher proportion of extraarticular manifestations, more erosions and require more aggressive treatments. (Rev Méd Chile 2001; 129: 253-8).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.3 20012001-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300003es10.4067/S0034-98872001000300003
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Aborigines
Rheumatic diseases
Arthritis rheumatoid
spellingShingle Aborigines
Rheumatic diseases
Arthritis rheumatoid
Kaliski K,Sonia
Bustos M,Luis
Artigas A,Carmen
Alarcón V,César
Vega V,Miguel Angel
Cárdenas R,Cristián
Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile
description Background: Mapuche, Chilean natives, represent approximately 9.8% of Chilean population and in the IX region of the country, they account for 18.4% of population over 15 years old. They preserve some socio-cultural characteristics that make them different to the rest of the population. Aim: To describe the epidemiological characteristics rheumatoid arthritis among Mapuche natives. Subjects and methods: Retrospective review of patients of Mapuche origin with rheumatoid arthritis, seen at Temuco Hospital between 1980 and 1996. Results: Among 308 cases gathered, only 106 (93 women, aged 55 ± 10 years old) complied with 1987 American College of Rheumatology (ACR) criteria for rheumatoid arthritis. The disease began between 29 and 52 years old in 73% of patients and the mean delay in diagnosis was 4.4 years. At diagnosis, 99% had symmetric poliarthritis, 28.3% had either fatigue, fever or weight loss, and 46.9% were in class III or in class IV of ACR-1991. Fifty three percent of patients developed Sicca syndrome, 36% developed nodules, 23% developed Raynaud phenomenon, 11% developed pulmonary involvement, 7% developed vasculitis, 5% developed neurological manifestations and 19% developed ophthalmologic involvement. Rheumatoid factor was positive in 78% and 73% had erosions. HLA DR4 was (+) in 60% of 30 patients. Thirty percent required 3 or more disease modifying drugs and prednisone over 10 mg/day. There was no correlation between functional capacity and several other features of the disease. Conclusions: Mapuche rheumatoid arthritis patients are detected late and have a poor functional capacity at the time of diagnosis. They also have a higher proportion of extraarticular manifestations, more erosions and require more aggressive treatments. (Rev Méd Chile 2001; 129: 253-8).
author Kaliski K,Sonia
Bustos M,Luis
Artigas A,Carmen
Alarcón V,César
Vega V,Miguel Angel
Cárdenas R,Cristián
author_facet Kaliski K,Sonia
Bustos M,Luis
Artigas A,Carmen
Alarcón V,César
Vega V,Miguel Angel
Cárdenas R,Cristián
author_sort Kaliski K,Sonia
title Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile
title_short Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile
title_full Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile
title_fullStr Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile
title_full_unstemmed Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile
title_sort artritis reumatoidea en población mapuche.: una experiencia de 16 años en la ix región de chile
publisher Sociedad Médica de Santiago
publishDate 2001
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300003
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