Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile
Background: Mapuche, Chilean natives, represent approximately 9.8% of Chilean population and in the IX region of the country, they account for 18.4% of population over 15 years old. They preserve some socio-cultural characteristics that make them different to the rest of the population. Aim: To desc...
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Sociedad Médica de Santiago
2001
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oai:scielo:S0034-988720010003000032001-05-22Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de ChileKaliski K,SoniaBustos M,LuisArtigas A,CarmenAlarcón V,CésarVega V,Miguel AngelCárdenas R,Cristián Aborigines Rheumatic diseases Arthritis rheumatoid Background: Mapuche, Chilean natives, represent approximately 9.8% of Chilean population and in the IX region of the country, they account for 18.4% of population over 15 years old. They preserve some socio-cultural characteristics that make them different to the rest of the population. Aim: To describe the epidemiological characteristics rheumatoid arthritis among Mapuche natives. Subjects and methods: Retrospective review of patients of Mapuche origin with rheumatoid arthritis, seen at Temuco Hospital between 1980 and 1996. Results: Among 308 cases gathered, only 106 (93 women, aged 55 ± 10 years old) complied with 1987 American College of Rheumatology (ACR) criteria for rheumatoid arthritis. The disease began between 29 and 52 years old in 73% of patients and the mean delay in diagnosis was 4.4 years. At diagnosis, 99% had symmetric poliarthritis, 28.3% had either fatigue, fever or weight loss, and 46.9% were in class III or in class IV of ACR-1991. Fifty three percent of patients developed Sicca syndrome, 36% developed nodules, 23% developed Raynaud phenomenon, 11% developed pulmonary involvement, 7% developed vasculitis, 5% developed neurological manifestations and 19% developed ophthalmologic involvement. Rheumatoid factor was positive in 78% and 73% had erosions. HLA DR4 was (+) in 60% of 30 patients. Thirty percent required 3 or more disease modifying drugs and prednisone over 10 mg/day. There was no correlation between functional capacity and several other features of the disease. Conclusions: Mapuche rheumatoid arthritis patients are detected late and have a poor functional capacity at the time of diagnosis. They also have a higher proportion of extraarticular manifestations, more erosions and require more aggressive treatments. (Rev Méd Chile 2001; 129: 253-8).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.3 20012001-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300003es10.4067/S0034-98872001000300003 |
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Scielo Chile |
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Scielo Chile |
language |
Spanish / Castilian |
topic |
Aborigines Rheumatic diseases Arthritis rheumatoid |
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Aborigines Rheumatic diseases Arthritis rheumatoid Kaliski K,Sonia Bustos M,Luis Artigas A,Carmen Alarcón V,César Vega V,Miguel Angel Cárdenas R,Cristián Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile |
description |
Background: Mapuche, Chilean natives, represent approximately 9.8% of Chilean population and in the IX region of the country, they account for 18.4% of population over 15 years old. They preserve some socio-cultural characteristics that make them different to the rest of the population. Aim: To describe the epidemiological characteristics rheumatoid arthritis among Mapuche natives. Subjects and methods: Retrospective review of patients of Mapuche origin with rheumatoid arthritis, seen at Temuco Hospital between 1980 and 1996. Results: Among 308 cases gathered, only 106 (93 women, aged 55 ± 10 years old) complied with 1987 American College of Rheumatology (ACR) criteria for rheumatoid arthritis. The disease began between 29 and 52 years old in 73% of patients and the mean delay in diagnosis was 4.4 years. At diagnosis, 99% had symmetric poliarthritis, 28.3% had either fatigue, fever or weight loss, and 46.9% were in class III or in class IV of ACR-1991. Fifty three percent of patients developed Sicca syndrome, 36% developed nodules, 23% developed Raynaud phenomenon, 11% developed pulmonary involvement, 7% developed vasculitis, 5% developed neurological manifestations and 19% developed ophthalmologic involvement. Rheumatoid factor was positive in 78% and 73% had erosions. HLA DR4 was (+) in 60% of 30 patients. Thirty percent required 3 or more disease modifying drugs and prednisone over 10 mg/day. There was no correlation between functional capacity and several other features of the disease. Conclusions: Mapuche rheumatoid arthritis patients are detected late and have a poor functional capacity at the time of diagnosis. They also have a higher proportion of extraarticular manifestations, more erosions and require more aggressive treatments. (Rev Méd Chile 2001; 129: 253-8). |
author |
Kaliski K,Sonia Bustos M,Luis Artigas A,Carmen Alarcón V,César Vega V,Miguel Angel Cárdenas R,Cristián |
author_facet |
Kaliski K,Sonia Bustos M,Luis Artigas A,Carmen Alarcón V,César Vega V,Miguel Angel Cárdenas R,Cristián |
author_sort |
Kaliski K,Sonia |
title |
Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile |
title_short |
Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile |
title_full |
Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile |
title_fullStr |
Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile |
title_full_unstemmed |
Artritis reumatoidea en población mapuche.: Una experiencia de 16 años en la IX región de Chile |
title_sort |
artritis reumatoidea en población mapuche.: una experiencia de 16 años en la ix región de chile |
publisher |
Sociedad Médica de Santiago |
publishDate |
2001 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300003 |
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