Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999

Background: Fortification of wheat flour with folic acid in Chile, started in January 2000. This fortification should decrease the incidence of neural tube defects. Aim: To study the incidence of neural tube defects among Chilean newborns, during 1999. Material and methods: The records of all newbor...

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Autores principales: Cortés M,Fanny, Mellado S,Cecilia, Hertrampf D,Eva, Alliende R,Angélica, Castillo T,Silvia
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2001
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300007
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spelling oai:scielo:S0034-988720010003000072001-05-22Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999Cortés M,FannyMellado S,CeciliaHertrampf D,EvaAlliende R,AngélicaCastillo T,Silvia Abnormalities Folic acid Neural tube defects Wheat Background: Fortification of wheat flour with folic acid in Chile, started in January 2000. This fortification should decrease the incidence of neural tube defects. Aim: To study the incidence of neural tube defects among Chilean newborns, during 1999. Material and methods: The records of all newborns and stillbirths with a birth weight over 500 g from 9 public maternity hospitals in Santiago in 1999, were reviewed. All neural tube defects, associated or not to other malformations were taken into account. Results: During the study period, 59.627 newborns and 455 stillbirths were analyzed. The global incidence of neural tube defects was 1.56 per 1.000 born (57% women, 42% men and 1% ambiguous sex). Spina bifida was the most frequent neural tube defect found. Conclusion: These baseline data will be useful to assess the impact of folic acid fortification of wheat flour. (Rev Méd Chile 2001; 129: 277-84).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.3 20012001-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300007es10.4067/S0034-98872001000300007
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Abnormalities
Folic acid
Neural tube defects
Wheat
spellingShingle Abnormalities
Folic acid
Neural tube defects
Wheat
Cortés M,Fanny
Mellado S,Cecilia
Hertrampf D,Eva
Alliende R,Angélica
Castillo T,Silvia
Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999
description Background: Fortification of wheat flour with folic acid in Chile, started in January 2000. This fortification should decrease the incidence of neural tube defects. Aim: To study the incidence of neural tube defects among Chilean newborns, during 1999. Material and methods: The records of all newborns and stillbirths with a birth weight over 500 g from 9 public maternity hospitals in Santiago in 1999, were reviewed. All neural tube defects, associated or not to other malformations were taken into account. Results: During the study period, 59.627 newborns and 455 stillbirths were analyzed. The global incidence of neural tube defects was 1.56 per 1.000 born (57% women, 42% men and 1% ambiguous sex). Spina bifida was the most frequent neural tube defect found. Conclusion: These baseline data will be useful to assess the impact of folic acid fortification of wheat flour. (Rev Méd Chile 2001; 129: 277-84).
author Cortés M,Fanny
Mellado S,Cecilia
Hertrampf D,Eva
Alliende R,Angélica
Castillo T,Silvia
author_facet Cortés M,Fanny
Mellado S,Cecilia
Hertrampf D,Eva
Alliende R,Angélica
Castillo T,Silvia
author_sort Cortés M,Fanny
title Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999
title_short Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999
title_full Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999
title_fullStr Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999
title_full_unstemmed Frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de Santiago durante el año 1999
title_sort frecuencia de los defectos de cierre del tubo neural en las maternidades públicas de santiago durante el año 1999
publisher Sociedad Médica de Santiago
publishDate 2001
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000300007
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