Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile
Background: Ambiguous sex has a great phenotypic variability and is a serious medical and social problem. Aim: To study the prevalence of ambiguous sex among newborns. Material and methods: As part of the ECLAMC (Cooperative Latin American Study of Congenital Malformations) all newborns with malform...
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Sociedad Médica de Santiago
2001
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oai:scielo:S0034-988720010005000062005-11-24Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de ChileHubner G,María EugeniaNazer H,JulioCifuentes O,Lucía Abnormalities Sex characteristics Sex differentiation Background: Ambiguous sex has a great phenotypic variability and is a serious medical and social problem. Aim: To study the prevalence of ambiguous sex among newborns. Material and methods: As part of the ECLAMC (Cooperative Latin American Study of Congenital Malformations) all newborns with malformations are registered and the next normal newborn is considered as a control. Results: 50.253 births occurred (between 1982 and 1999) in the University of Chile Maternity Hospital. The rate of congenital malformations was 6.78% and the prevalence of ambiguous sex was 4.7 per 10.000 births. Affected children had a lower birth weight, lower gestational age and a lower maternal age than controls. The most frequent associated malformations were of the urinary (64%) and cardiovascular systems (60.7%). Thirty two percent of affected children had specific syndromes. Conclusions: The prevalence of ambiguous sex in this study was 4.7 per 10.000 births, which is higher than that reported in the ECLAMC (1.9 per 10000). (Rev Méd Chile 2001; 129: 509-14)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.5 20012001-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500006es10.4067/S0034-98872001000500006 |
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Scielo Chile |
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Scielo Chile |
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Spanish / Castilian |
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Abnormalities Sex characteristics Sex differentiation |
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Abnormalities Sex characteristics Sex differentiation Hubner G,María Eugenia Nazer H,Julio Cifuentes O,Lucía Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile |
description |
Background: Ambiguous sex has a great phenotypic variability and is a serious medical and social problem. Aim: To study the prevalence of ambiguous sex among newborns. Material and methods: As part of the ECLAMC (Cooperative Latin American Study of Congenital Malformations) all newborns with malformations are registered and the next normal newborn is considered as a control. Results: 50.253 births occurred (between 1982 and 1999) in the University of Chile Maternity Hospital. The rate of congenital malformations was 6.78% and the prevalence of ambiguous sex was 4.7 per 10.000 births. Affected children had a lower birth weight, lower gestational age and a lower maternal age than controls. The most frequent associated malformations were of the urinary (64%) and cardiovascular systems (60.7%). Thirty two percent of affected children had specific syndromes. Conclusions: The prevalence of ambiguous sex in this study was 4.7 per 10.000 births, which is higher than that reported in the ECLAMC (1.9 per 10000). (Rev Méd Chile 2001; 129: 509-14) |
author |
Hubner G,María Eugenia Nazer H,Julio Cifuentes O,Lucía |
author_facet |
Hubner G,María Eugenia Nazer H,Julio Cifuentes O,Lucía |
author_sort |
Hubner G,María Eugenia |
title |
Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile |
title_short |
Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile |
title_full |
Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile |
title_fullStr |
Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile |
title_full_unstemmed |
Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile |
title_sort |
sexo ambiguo: prevalencia al nacimiento en la maternidad del hospital clínico de la universidad de chile |
publisher |
Sociedad Médica de Santiago |
publishDate |
2001 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500006 |
work_keys_str_mv |
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1718435970770010112 |