Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile

Background: Ambiguous sex has a great phenotypic variability and is a serious medical and social problem. Aim: To study the prevalence of ambiguous sex among newborns. Material and methods: As part of the ECLAMC (Cooperative Latin American Study of Congenital Malformations) all newborns with malform...

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Autores principales: Hubner G,María Eugenia, Nazer H,Julio, Cifuentes O,Lucía
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2001
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500006
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spelling oai:scielo:S0034-988720010005000062005-11-24Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de ChileHubner G,María EugeniaNazer H,JulioCifuentes O,Lucía Abnormalities Sex characteristics Sex differentiation Background: Ambiguous sex has a great phenotypic variability and is a serious medical and social problem. Aim: To study the prevalence of ambiguous sex among newborns. Material and methods: As part of the ECLAMC (Cooperative Latin American Study of Congenital Malformations) all newborns with malformations are registered and the next normal newborn is considered as a control. Results: 50.253 births occurred (between 1982 and 1999) in the University of Chile Maternity Hospital. The rate of congenital malformations was 6.78% and the prevalence of ambiguous sex was 4.7 per 10.000 births. Affected children had a lower birth weight, lower gestational age and a lower maternal age than controls. The most frequent associated malformations were of the urinary (64%) and cardiovascular systems (60.7%). Thirty two percent of affected children had specific syndromes. Conclusions: The prevalence of ambiguous sex in this study was 4.7 per 10.000 births, which is higher than that reported in the ECLAMC (1.9 per 10000). (Rev Méd Chile 2001; 129: 509-14)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.5 20012001-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500006es10.4067/S0034-98872001000500006
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Abnormalities
Sex characteristics
Sex differentiation
spellingShingle Abnormalities
Sex characteristics
Sex differentiation
Hubner G,María Eugenia
Nazer H,Julio
Cifuentes O,Lucía
Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile
description Background: Ambiguous sex has a great phenotypic variability and is a serious medical and social problem. Aim: To study the prevalence of ambiguous sex among newborns. Material and methods: As part of the ECLAMC (Cooperative Latin American Study of Congenital Malformations) all newborns with malformations are registered and the next normal newborn is considered as a control. Results: 50.253 births occurred (between 1982 and 1999) in the University of Chile Maternity Hospital. The rate of congenital malformations was 6.78% and the prevalence of ambiguous sex was 4.7 per 10.000 births. Affected children had a lower birth weight, lower gestational age and a lower maternal age than controls. The most frequent associated malformations were of the urinary (64%) and cardiovascular systems (60.7%). Thirty two percent of affected children had specific syndromes. Conclusions: The prevalence of ambiguous sex in this study was 4.7 per 10.000 births, which is higher than that reported in the ECLAMC (1.9 per 10000). (Rev Méd Chile 2001; 129: 509-14)
author Hubner G,María Eugenia
Nazer H,Julio
Cifuentes O,Lucía
author_facet Hubner G,María Eugenia
Nazer H,Julio
Cifuentes O,Lucía
author_sort Hubner G,María Eugenia
title Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile
title_short Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile
title_full Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile
title_fullStr Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile
title_full_unstemmed Sexo ambiguo: prevalencia al nacimiento en la maternidad del Hospital Clínico de la Universidad de Chile
title_sort sexo ambiguo: prevalencia al nacimiento en la maternidad del hospital clínico de la universidad de chile
publisher Sociedad Médica de Santiago
publishDate 2001
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500006
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