Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90

Background: Sanitary and socioeconomic changes and the identification of new causative virus, have changed the epidemiology of hepatitis in Chile. Aim: To study the natural history of acute hepatitis caused by virus A, E and non A-E in Chilean adults. Patients and methods: A special study protocol w...

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Autores principales:	Ibarra V,Humberto, Riedemann G,Stella, Siegel G,Freddy, Toledo A,Claudio, Reinhardt V,Germán
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Epidemiology Hepatitis A virus, human Hepatitis antibodies Hepatitis B Hepatitis C Hepatitis D Hepatitis E
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500008
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spelling	oai:scielo:S0034-988720010005000082005-11-24Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90Ibarra V,HumbertoRiedemann G,StellaSiegel G,FreddyToledo A,ClaudioReinhardt V,Germán Epidemiology Hepatitis A virus, human Hepatitis antibodies Hepatitis B Hepatitis C Hepatitis D Hepatitis E Background: Sanitary and socioeconomic changes and the identification of new causative virus, have changed the epidemiology of hepatitis in Chile. Aim: To study the natural history of acute hepatitis caused by virus A, E and non A-E in Chilean adults. Patients and methods: A special study protocol was followed for patients with a clinical picture of acute hepatitis. Anti HAV IgM, anti HBc IgM, anti HEV IgG and IgM and Anti HCV antibodies were determined by ELISA. Results: Fifty nine patients (30 male), aged 15 to 58 years old were studied. Eighty nine percent had jaundice and 50 to 70% had malaise and abdominal pain. Virus A was positive in 80%, virus E in 7%. In 14% of patients, all viral markers were negative. The evolution was typical in 78%, biphasic in 14% and cholestatic in 5%. One patient had a prolonged and one a fulminant course. Mean ALT was 1148 U/l and mean total bilirubin was 5.5 mg/dl. Seventy three percent of cases occurred during early winter and spring and 27% during summer and early autumm. Conclusions: The main etiology of acute viral hepatitis in Chile is virus A and most cases occur during the rainy season. Clinical features of hepatitis non A-E are similar to enteral transmission forms. (Rev Méd Chile 2001; 129: 523-30)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.5 20012001-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500008es10.4067/S0034-98872001000500008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Epidemiology Hepatitis A virus, human Hepatitis antibodies Hepatitis B Hepatitis C Hepatitis D Hepatitis E
spellingShingle	Epidemiology Hepatitis A virus, human Hepatitis antibodies Hepatitis B Hepatitis C Hepatitis D Hepatitis E Ibarra V,Humberto Riedemann G,Stella Siegel G,Freddy Toledo A,Claudio Reinhardt V,Germán Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90
description	Background: Sanitary and socioeconomic changes and the identification of new causative virus, have changed the epidemiology of hepatitis in Chile. Aim: To study the natural history of acute hepatitis caused by virus A, E and non A-E in Chilean adults. Patients and methods: A special study protocol was followed for patients with a clinical picture of acute hepatitis. Anti HAV IgM, anti HBc IgM, anti HEV IgG and IgM and Anti HCV antibodies were determined by ELISA. Results: Fifty nine patients (30 male), aged 15 to 58 years old were studied. Eighty nine percent had jaundice and 50 to 70% had malaise and abdominal pain. Virus A was positive in 80%, virus E in 7%. In 14% of patients, all viral markers were negative. The evolution was typical in 78%, biphasic in 14% and cholestatic in 5%. One patient had a prolonged and one a fulminant course. Mean ALT was 1148 U/l and mean total bilirubin was 5.5 mg/dl. Seventy three percent of cases occurred during early winter and spring and 27% during summer and early autumm. Conclusions: The main etiology of acute viral hepatitis in Chile is virus A and most cases occur during the rainy season. Clinical features of hepatitis non A-E are similar to enteral transmission forms. (Rev Méd Chile 2001; 129: 523-30)
author	Ibarra V,Humberto Riedemann G,Stella Siegel G,Freddy Toledo A,Claudio Reinhardt V,Germán
author_facet	Ibarra V,Humberto Riedemann G,Stella Siegel G,Freddy Toledo A,Claudio Reinhardt V,Germán
author_sort	Ibarra V,Humberto
title	Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90
title_short	Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90
title_full	Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90
title_fullStr	Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90
title_full_unstemmed	Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90
title_sort	hepatitis aguda por virus a, e y no a-e en adultos chilenos a fines de los años 90
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000500008
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Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90

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