Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos

Background: Follow-up of celiac patients in Chile is often interrupted when adolescents are referred to adult gastroenterologists. Aim: To study the evolution of patients with celiac disease when they reach adolescence or young adulthood. Patients and methods: Current adherence to gluten-free diet a...

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Autores principales:	Roessler B,José Luis, Ríos M,Gloria, Alarcón O,Teresa, Bergenfreid O,Carmen, Mondragón O,Alexandra, Araya Q,Magdalena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Antibodies, antiendomysial Celiac disease, Gluten Jejunal diseases
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000700006
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spelling	oai:scielo:S0034-988720010007000062005-11-22Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultosRoessler B,José LuisRíos M,GloriaAlarcón O,TeresaBergenfreid O,CarmenMondragón O,AlexandraAraya Q,Magdalena Antibodies, antiendomysial Celiac disease, Gluten Jejunal diseases Background: Follow-up of celiac patients in Chile is often interrupted when adolescents are referred to adult gastroenterologists. Aim: To study the evolution of patients with celiac disease when they reach adolescence or young adulthood. Patients and methods: Current adherence to gluten-free diet and its relation to symptoms and circulating antiendomysial antibodies were evaluated in the 58 confirmed celiac patients older than 12 years of age controlled at 3 hospitals in Santiago. Results: Mean age at the moment of this assessment was 17.8 ± 5 years, 65.5% were women, 12.5% were at nutritional risk (-IDS) while 20% were overweight/obese. Although all patients declared themselves asymptomatic, a focused questionnaire revealed that 26% suffered some symptoms. Only 24.1% followed a strict gluten-free diet. Eight of 20 patients who ate gluten-containing diets had negative antiendomysial antibodies (EMA), three of whom turned positive within 6 to 9 months. In three of four (asymptomatic) cases that accepted a new jejunal biopsy, histology was abnormal. One patient who followed a strict diet had EMA (+) and normal histology. Conclusions: These results confirm that after childhood, symptoms abate significantly in celiac patients. The observed sensitivity and specificity of EMA makes necessary to maintain small intestinal biopsies as the gold standard for diagnosis and confirmation of the disease. (Rev Méd Chile 2001; 743-8)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.7 20012001-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000700006es10.4067/S0034-98872001000700006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antibodies, antiendomysial Celiac disease, Gluten Jejunal diseases
spellingShingle	Antibodies, antiendomysial Celiac disease, Gluten Jejunal diseases Roessler B,José Luis Ríos M,Gloria Alarcón O,Teresa Bergenfreid O,Carmen Mondragón O,Alexandra Araya Q,Magdalena Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos
description	Background: Follow-up of celiac patients in Chile is often interrupted when adolescents are referred to adult gastroenterologists. Aim: To study the evolution of patients with celiac disease when they reach adolescence or young adulthood. Patients and methods: Current adherence to gluten-free diet and its relation to symptoms and circulating antiendomysial antibodies were evaluated in the 58 confirmed celiac patients older than 12 years of age controlled at 3 hospitals in Santiago. Results: Mean age at the moment of this assessment was 17.8 ± 5 years, 65.5% were women, 12.5% were at nutritional risk (-IDS) while 20% were overweight/obese. Although all patients declared themselves asymptomatic, a focused questionnaire revealed that 26% suffered some symptoms. Only 24.1% followed a strict gluten-free diet. Eight of 20 patients who ate gluten-containing diets had negative antiendomysial antibodies (EMA), three of whom turned positive within 6 to 9 months. In three of four (asymptomatic) cases that accepted a new jejunal biopsy, histology was abnormal. One patient who followed a strict diet had EMA (+) and normal histology. Conclusions: These results confirm that after childhood, symptoms abate significantly in celiac patients. The observed sensitivity and specificity of EMA makes necessary to maintain small intestinal biopsies as the gold standard for diagnosis and confirmation of the disease. (Rev Méd Chile 2001; 743-8)
author	Roessler B,José Luis Ríos M,Gloria Alarcón O,Teresa Bergenfreid O,Carmen Mondragón O,Alexandra Araya Q,Magdalena
author_facet	Roessler B,José Luis Ríos M,Gloria Alarcón O,Teresa Bergenfreid O,Carmen Mondragón O,Alexandra Araya Q,Magdalena
author_sort	Roessler B,José Luis
title	Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos
title_short	Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos
title_full	Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos
title_fullStr	Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos
title_full_unstemmed	Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos
title_sort	enfermedad celíaca en el adolescente y adulto joven.: un desafío para gastroenterólogos de niños y adultos
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000700006
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Enfermedad celíaca en el adolescente y adulto joven.: Un desafío para gastroenterólogos de niños y adultos

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