"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados

We report a 54 years old male that received a renal allograft without complications. One year after the transplantation, she was receiving cyclosporine doses of 2 to 3 mg/kg and maintained serum levels of 60 to 90 mg/dl. An abrupt increase in cyclosporine serum levels to 469 and 600 mg/dl was noted...

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Autores principales:	Duclos H,Jaime, Goecke S,Helmuth
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Cyclosporine Medicine, herbal Transplantation, kidney
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000700013
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spelling	oai:scielo:S0034-988720010007000132005-11-22"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantadosDuclos H,JaimeGoecke S,Helmuth Cyclosporine Medicine, herbal Transplantation, kidney We report a 54 years old male that received a renal allograft without complications. One year after the transplantation, she was receiving cyclosporine doses of 2 to 3 mg/kg and maintained serum levels of 60 to 90 mg/dl. An abrupt increase in cyclosporine serum levels to 469 and 600 mg/dl was noted after 15 months of transplantation. After a careful interrogation the patient admitted the use of Geum chiloense ("hierba del clavo"). Discontinuing this herbal remedy, cyclosporine levels decreased to 55 mg/dl, despite the maintenance of the same cyclosporine dose. The potential side effects of herbal remedies must be borne in mind (Rev Méd Chile 2001; 129: 789-90).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.7 20012001-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000700013es10.4067/S0034-98872001000700013
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cyclosporine Medicine, herbal Transplantation, kidney
spellingShingle	Cyclosporine Medicine, herbal Transplantation, kidney Duclos H,Jaime Goecke S,Helmuth "Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados
description	We report a 54 years old male that received a renal allograft without complications. One year after the transplantation, she was receiving cyclosporine doses of 2 to 3 mg/kg and maintained serum levels of 60 to 90 mg/dl. An abrupt increase in cyclosporine serum levels to 469 and 600 mg/dl was noted after 15 months of transplantation. After a careful interrogation the patient admitted the use of Geum chiloense ("hierba del clavo"). Discontinuing this herbal remedy, cyclosporine levels decreased to 55 mg/dl, despite the maintenance of the same cyclosporine dose. The potential side effects of herbal remedies must be borne in mind (Rev Méd Chile 2001; 129: 789-90).
author	Duclos H,Jaime Goecke S,Helmuth
author_facet	Duclos H,Jaime Goecke S,Helmuth
author_sort	Duclos H,Jaime
title	"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados
title_short	"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados
title_full	"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados
title_fullStr	"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados
title_full_unstemmed	"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados
title_sort	"hierba del clavo" (geum chiloense) interfiere niveles de ciclosporina: potencial riesgo para trasplantados
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000700013
work_keys_str_mv	AT ducloshjaime hierbadelclavogeumchiloenseinterfierenivelesdeciclosporinapotencialriesgoparatrasplantados AT goeckeshelmuth hierbadelclavogeumchiloenseinterfierenivelesdeciclosporinapotencialriesgoparatrasplantados
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"Hierba del Clavo" (Geum chiloense) interfiere niveles de ciclosporina: Potencial riesgo para trasplantados

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