Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES

Background: PRONARES (Programa Nacional de Vigilancia de Resistencia) is a national surveillance program for antimicrobial susceptibility, focused in different syndromes and among these, urinary tract infections. The work is done in a laboratory net that uses common protocols and whose data are cent...

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Autores principales:	Prado J,Valeria, Trucco A,Olivia, Durán T,Claudia, Mamani J,Rosana, Royer F,Michel
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Anti-infective agents, urinary Infection control Pediatrics Urinary tract
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000800006
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spelling	oai:scielo:S0034-988720010008000062001-10-29Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARESPrado J,ValeriaTrucco A,OliviaDurán T,ClaudiaMamani J,RosanaRoyer F,Michel Anti-infective agents, urinary Infection control Pediatrics Urinary tract Background: PRONARES (Programa Nacional de Vigilancia de Resistencia) is a national surveillance program for antimicrobial susceptibility, focused in different syndromes and among these, urinary tract infections. The work is done in a laboratory net that uses common protocols and whose data are centrally analyzed using the WHONET program. Aim: To analyze the pattern of antimicrobial susceptibility of agents causing urinary infections in children in the period 1997-1999. Material and methods: In the study period, 5,525 strains were analyzed. Of these, 2,307 came from pediatric patients (1,495 hospitalized and 803 ambulatory). Results: The most common causative agent was E. coli in 74,2% of cases, followed by Klebsiella spp in 8,2% and other agents in a lower frequency. Of E. coli strains, 74% were resistant to ampicillin, 52% to clotrimoxazole and 30% to first generation cephalosporins. These strains were sensitive to second and third generation cephalosporins, aminoglycosides, ciprofloxacin and nitrofurantoin. Strains from nosocomial or community infections had similar antimicrobial susceptibility. Klebsiella spp had a high rate of antimicrobial resistance (over 40%), that was even higher among nosocomial strains. It was 90% susceptible to ciprofloxacin and 100% to imipenem. All centers from which strains came had a similar pattern of susceptibility, with the exception of a pediatric center that had significantly higher resistance levels. Conclusions: The current therapeutic recommendations for urinary tract infections in children caused by E coli, are still pertinent, but the use of first generation cephalosporins must be cautious. The treatment of Klebsiella spp requires an individual antibiogram (Rev Méd Chile 2001; 129: 877-885).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.8 20012001-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000800006es10.4067/S0034-98872001000800006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Anti-infective agents, urinary Infection control Pediatrics Urinary tract
spellingShingle	Anti-infective agents, urinary Infection control Pediatrics Urinary tract Prado J,Valeria Trucco A,Olivia Durán T,Claudia Mamani J,Rosana Royer F,Michel Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES
description	Background: PRONARES (Programa Nacional de Vigilancia de Resistencia) is a national surveillance program for antimicrobial susceptibility, focused in different syndromes and among these, urinary tract infections. The work is done in a laboratory net that uses common protocols and whose data are centrally analyzed using the WHONET program. Aim: To analyze the pattern of antimicrobial susceptibility of agents causing urinary infections in children in the period 1997-1999. Material and methods: In the study period, 5,525 strains were analyzed. Of these, 2,307 came from pediatric patients (1,495 hospitalized and 803 ambulatory). Results: The most common causative agent was E. coli in 74,2% of cases, followed by Klebsiella spp in 8,2% and other agents in a lower frequency. Of E. coli strains, 74% were resistant to ampicillin, 52% to clotrimoxazole and 30% to first generation cephalosporins. These strains were sensitive to second and third generation cephalosporins, aminoglycosides, ciprofloxacin and nitrofurantoin. Strains from nosocomial or community infections had similar antimicrobial susceptibility. Klebsiella spp had a high rate of antimicrobial resistance (over 40%), that was even higher among nosocomial strains. It was 90% susceptible to ciprofloxacin and 100% to imipenem. All centers from which strains came had a similar pattern of susceptibility, with the exception of a pediatric center that had significantly higher resistance levels. Conclusions: The current therapeutic recommendations for urinary tract infections in children caused by E coli, are still pertinent, but the use of first generation cephalosporins must be cautious. The treatment of Klebsiella spp requires an individual antibiogram (Rev Méd Chile 2001; 129: 877-885).
author	Prado J,Valeria Trucco A,Olivia Durán T,Claudia Mamani J,Rosana Royer F,Michel
author_facet	Prado J,Valeria Trucco A,Olivia Durán T,Claudia Mamani J,Rosana Royer F,Michel
author_sort	Prado J,Valeria
title	Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES
title_short	Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES
title_full	Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES
title_fullStr	Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES
title_full_unstemmed	Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES
title_sort	perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: programa de vigilancia pronares
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000800006
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Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES

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