Impacto de los factores de riesgo coronario en mujeres de edad media
Background: In Chile, 40% of deaths due to acute myocardial infarction occur in women. Aim: To assess the presence of cardiovascular risk factors in women with acute coronary syndromes. Patients and methods: Thirty four women aged 46 to 55 years old, admitted to the hospital due to an acute coronary...
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| Autores principales: | , , , , |
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| Lenguaje: | Spanish / Castilian |
| Publicado: |
Sociedad Médica de Santiago
2001
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| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000900004 |
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| Sumario: | Background: In Chile, 40% of deaths due to acute myocardial infarction occur in women. Aim: To assess the presence of cardiovascular risk factors in women with acute coronary syndromes. Patients and methods: Thirty four women aged 46 to 55 years old, admitted to the hospital due to an acute coronary syndrome and 102 age matched healthy women were studied. A clinical history was obtained, blood pressure and fasting serum lipids were measured. Results: A history of high blood pressure was present in 65 and 16% of patients and healthy controls respectively. Seventy seven percent of patients and 36% of controls smoked, 76% of patients and 48% of controls were postmenopausal, 21% of patients an 5% of controls were diabetic. In patients and controls respectively serum total cholesterol was 230.1±36.2 and 211.2±34.8 mg/dl, serum triacylglycerol was 213.4±109.4 and 143.2±76.9 mg/dl and serum HDL cholesterol was 44.1±10.8 and 49.8±13.3 mg/dl (p<0.001 or less). In univariate analysis, the risk of acute coronary syndrome increased with high blood pressure (OR: 9.3, CI: 2.5-18.6), menopause (OR: 8.3, CI: 2,2-31:5), smoking (OR: 6.9, CI: 2.5-18.6), diabetes mellitus (OR: 5.0, CI: 1.4-17.5), a high total cholesterol/HDL cholesterol ratio (OR: 6.6, CI: 1.8-12.5) and hypertriglyceridemia (OR: 3.6, CI: 1.5-8.5). Logistic regression analysis showed that hypertension and menopause had the higher predictive values for acute coronary syndrome. Conclusions: In this group of women with acute coronary syndromes, the main coronary risk factors were high blood pressure and menopause (Rev Méd Chile 2001; 129: 995-1002) |
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