Diabetes mellitus inducida por olanzapina: Caso clínico

Atypical antipsychotics are widely used in psychotic disorders, refractory to conventional neuroleptic agents. They induce minimal extra pyramidal side effects, probably due to their greater affinity for certain dopaminergic receptors. However, this polyreceptor affinity may be responsible for the d...

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Autores principales:	Rojas G,Paula, Arancibia S,Pablo, Bravo S,Verónica, Varela G,Susana
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Antipsychotic Agents Diabetes Mellitus Drug Toxicity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001000011
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spelling	oai:scielo:S0034-988720010010000112005-11-14Diabetes mellitus inducida por olanzapina: Caso clínicoRojas G,PaulaArancibia S,PabloBravo S,VerónicaVarela G,Susana Antipsychotic Agents Diabetes Mellitus Drug Toxicity Atypical antipsychotics are widely used in psychotic disorders, refractory to conventional neuroleptic agents. They induce minimal extra pyramidal side effects, probably due to their greater affinity for certain dopaminergic receptors. However, this polyreceptor affinity may be responsible for the development of other side effects. We report a 48 years old male drinker and addicted to cocaine, that after two months of Olanzapine use, developed a severe diabetes mellitus with fasting blood glucose values reaching 514 mg/dl. When he was admitted to the hospital, physical examination was normal and his body mass index was 28 kg/m2. Olanzapine was discontinued and blood glucose values gradually returned to normal. After two months of follow up, the patient is on dietary treatment and with a fasting glucose of 132 mg/dl (Rev Méd Chile 2001; 129: 1183-85)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.10 20012001-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001000011es10.4067/S0034-98872001001000011
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antipsychotic Agents Diabetes Mellitus Drug Toxicity
spellingShingle	Antipsychotic Agents Diabetes Mellitus Drug Toxicity Rojas G,Paula Arancibia S,Pablo Bravo S,Verónica Varela G,Susana Diabetes mellitus inducida por olanzapina: Caso clínico
description	Atypical antipsychotics are widely used in psychotic disorders, refractory to conventional neuroleptic agents. They induce minimal extra pyramidal side effects, probably due to their greater affinity for certain dopaminergic receptors. However, this polyreceptor affinity may be responsible for the development of other side effects. We report a 48 years old male drinker and addicted to cocaine, that after two months of Olanzapine use, developed a severe diabetes mellitus with fasting blood glucose values reaching 514 mg/dl. When he was admitted to the hospital, physical examination was normal and his body mass index was 28 kg/m2. Olanzapine was discontinued and blood glucose values gradually returned to normal. After two months of follow up, the patient is on dietary treatment and with a fasting glucose of 132 mg/dl (Rev Méd Chile 2001; 129: 1183-85)
author	Rojas G,Paula Arancibia S,Pablo Bravo S,Verónica Varela G,Susana
author_facet	Rojas G,Paula Arancibia S,Pablo Bravo S,Verónica Varela G,Susana
author_sort	Rojas G,Paula
title	Diabetes mellitus inducida por olanzapina: Caso clínico
title_short	Diabetes mellitus inducida por olanzapina: Caso clínico
title_full	Diabetes mellitus inducida por olanzapina: Caso clínico
title_fullStr	Diabetes mellitus inducida por olanzapina: Caso clínico
title_full_unstemmed	Diabetes mellitus inducida por olanzapina: Caso clínico
title_sort	diabetes mellitus inducida por olanzapina: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001000011
work_keys_str_mv	AT rojasgpaula diabetesmellitusinducidaporolanzapinacasoclinico AT arancibiaspablo diabetesmellitusinducidaporolanzapinacasoclinico AT bravosveronica diabetesmellitusinducidaporolanzapinacasoclinico AT varelagsusana diabetesmellitusinducidaporolanzapinacasoclinico
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Diabetes mellitus inducida por olanzapina: Caso clínico

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