Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas

Background: There are changes in inspiratory breath sound intensity in patients with airway obstruction. Airway narrowing may change sound spectral characteristics. Aim: To define the characteristics of lung sounds at standardized air flow during methacholine challenge and to compare acoustic change...

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Autores principales:	Sánchez D,Ignacio, Alvarez G,Cecilia, Clavería R,Cristián, Lisboa B,Carmen
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Asthma Anti-asthmatic agents Lung diseases, obstructive Methacholine chloride
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100006
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spelling	oai:scielo:S0034-988720010011000062002-06-12Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricasSánchez D,IgnacioAlvarez G,CeciliaClavería R,CristiánLisboa B,Carmen Asthma Anti-asthmatic agents Lung diseases, obstructive Methacholine chloride Background: There are changes in inspiratory breath sound intensity in patients with airway obstruction. Airway narrowing may change sound spectral characteristics. Aim: To define the characteristics of lung sounds at standardized air flow during methacholine challenge and to compare acoustic changes with transcutaneous oxygen tension (PtcO2) during induced airway narrowing. Patients and methods: Forty asthmatic children (20 male) aged 5.2±1 years and 40 normal children (18 male), aged 5.6 ± 1 years were studied. All patients were free of respiratory tract infections one month before the study. A methacholine challenge from 0.06 to 8 mg/ml was performed; the test was ended when a fall in PtcO2 of >20% from baseline was observed or if the final concentration was reached. Subjects breathed through a pneumotachograph aiming at flows of 0.4 to 0.6 l/s. Respiratory sounds were recorded using contact sensors at the suprasternal notch and at the posterior right lower lobe. From average spectra, power at low (100-200 Hz=P1) and high frequencies (400-2000 =P2) was calculated. Frequencies below which 50% (F50) and 99% (SEF90) of the spectral power between 100 and 2000 Hz was contained, were also calculated. Results: In asthmatics, the metacholine concentration at which a 20% fall in PtcO2 was observed, was lower than in normal children (p< 0.05). There was an increase in P1 (p<0.01) and a reduction in P2 (p<0.01) during inspiration, in subjects that experienced a 20% reduction in PtcO2. Also, there was an increase in F50 and SEF99 during inspiration in lung sounds, but not over the trachea. Conclusions: Lung sounds analysis can be useful for the assessment of airway reactivity in asthmatic children (Rev Méd Chile 2001; 129: 1271-8)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.11 20012001-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100006es10.4067/S0034-98872001001100006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Asthma Anti-asthmatic agents Lung diseases, obstructive Methacholine chloride
spellingShingle	Asthma Anti-asthmatic agents Lung diseases, obstructive Methacholine chloride Sánchez D,Ignacio Alvarez G,Cecilia Clavería R,Cristián Lisboa B,Carmen Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas
description	Background: There are changes in inspiratory breath sound intensity in patients with airway obstruction. Airway narrowing may change sound spectral characteristics. Aim: To define the characteristics of lung sounds at standardized air flow during methacholine challenge and to compare acoustic changes with transcutaneous oxygen tension (PtcO2) during induced airway narrowing. Patients and methods: Forty asthmatic children (20 male) aged 5.2±1 years and 40 normal children (18 male), aged 5.6 ± 1 years were studied. All patients were free of respiratory tract infections one month before the study. A methacholine challenge from 0.06 to 8 mg/ml was performed; the test was ended when a fall in PtcO2 of >20% from baseline was observed or if the final concentration was reached. Subjects breathed through a pneumotachograph aiming at flows of 0.4 to 0.6 l/s. Respiratory sounds were recorded using contact sensors at the suprasternal notch and at the posterior right lower lobe. From average spectra, power at low (100-200 Hz=P1) and high frequencies (400-2000 =P2) was calculated. Frequencies below which 50% (F50) and 99% (SEF90) of the spectral power between 100 and 2000 Hz was contained, were also calculated. Results: In asthmatics, the metacholine concentration at which a 20% fall in PtcO2 was observed, was lower than in normal children (p< 0.05). There was an increase in P1 (p<0.01) and a reduction in P2 (p<0.01) during inspiration, in subjects that experienced a 20% reduction in PtcO2. Also, there was an increase in F50 and SEF99 during inspiration in lung sounds, but not over the trachea. Conclusions: Lung sounds analysis can be useful for the assessment of airway reactivity in asthmatic children (Rev Méd Chile 2001; 129: 1271-8)
author	Sánchez D,Ignacio Alvarez G,Cecilia Clavería R,Cristián Lisboa B,Carmen
author_facet	Sánchez D,Ignacio Alvarez G,Cecilia Clavería R,Cristián Lisboa B,Carmen
author_sort	Sánchez D,Ignacio
title	Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas
title_short	Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas
title_full	Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas
title_fullStr	Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas
title_full_unstemmed	Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas
title_sort	análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100006
work_keys_str_mv	AT sanchezdignacio analisiscomputacionaldelosruidosrespiratoriosenlaevaluaciondelaobstruccionbronquialenninospequenosquenocolaboranconlaspruebasespirometricas AT alvarezgcecilia analisiscomputacionaldelosruidosrespiratoriosenlaevaluaciondelaobstruccionbronquialenninospequenosquenocolaboranconlaspruebasespirometricas AT claveriarcristian analisiscomputacionaldelosruidosrespiratoriosenlaevaluaciondelaobstruccionbronquialenninospequenosquenocolaboranconlaspruebasespirometricas AT lisboabcarmen analisiscomputacionaldelosruidosrespiratoriosenlaevaluaciondelaobstruccionbronquialenninospequenosquenocolaboranconlaspruebasespirometricas
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Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas

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