Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)

Background: Pediatric patients in treatment for cancer can have fatal bacterial infections. Thus, in the presence of fever or other signs infection, antimicrobials have to be prescribed empirically. Aim: To know the causative agents of bacteremia in children with cancer, their changes with time and...

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Autores principales:	Payá G,Ernesto, Alvarez P,Ana María, Avilés L,Carmen, Cofré G,José, Enríquez O,Nancy, Salgado M,Carmen, Santolaya de P,María Elena, Silva G,Pamela, Tordecilla C,Juan, Varas P,Mónica, Villarroel C,Milena, Zubieta A,Marcela
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Bacteremia Bacterial infections Infection control, Neoplasms
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100009
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spelling	oai:scielo:S0034-988720010011000092002-06-12Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)Payá G,ErnestoAlvarez P,Ana MaríaAvilés L,CarmenCofré G,JoséEnríquez O,NancySalgado M,CarmenSantolaya de P,María ElenaSilva G,PamelaTordecilla C,JuanVaras P,MónicaVillarroel C,MilenaZubieta A,Marcela Bacteremia Bacterial infections Infection control, Neoplasms Background: Pediatric patients in treatment for cancer can have fatal bacterial infections. Thus, in the presence of fever or other signs infection, antimicrobials have to be prescribed empirically. Aim: To know the causative agents of bacteremia in children with cancer, their changes with time and between different hospitals and their patterns of susceptibility. Material and methods: We reviewed the blood cultores of children with cancer in five hospitals of Santiago, from 1994 at 1998. Results: During the study period, 707 agents were isolated. The most frequently isolated species or genus were coagulase negative Staphylococcus (43%), Staphylococcus aureus (16%), Escherichia coli (9%), Klebsiella spp. (8%), Pseudomonas spp. (5%) and Candida spp. (4%). Coagulase negative Staphylococcus was 55% resistant to meticilin and S. aureus was 44% resistant. Enterobacteriae had 15% resistance to gentamicin and amikacin, 2% to imipenem, 26% to ceftriaxone, 21% to cefotaxim and 20% to ceftazidim. Among non fermenting agents resistance was 6% for imipenem, 9% for amikacin 10% for ciprofloxacin, 19% for ceftazidim and 22% for cefoperazone. The resistance of Streptococcus spp. (non pneumoniae) to penicillin reached 50% and that of Enterococcus spp. was of 33%. Conclusions: Treatment for pediatric patients with cancer must be modified and new guidelines including more active medications for patients at risk for bacteremia, should be devised (Rev Méd Chile 2001; 129: 1297-1304)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.11 20012001-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100009es10.4067/S0034-98872001001100009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Bacteremia Bacterial infections Infection control, Neoplasms
spellingShingle	Bacteremia Bacterial infections Infection control, Neoplasms Payá G,Ernesto Alvarez P,Ana María Avilés L,Carmen Cofré G,José Enríquez O,Nancy Salgado M,Carmen Santolaya de P,María Elena Silva G,Pamela Tordecilla C,Juan Varas P,Mónica Villarroel C,Milena Zubieta A,Marcela Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)
description	Background: Pediatric patients in treatment for cancer can have fatal bacterial infections. Thus, in the presence of fever or other signs infection, antimicrobials have to be prescribed empirically. Aim: To know the causative agents of bacteremia in children with cancer, their changes with time and between different hospitals and their patterns of susceptibility. Material and methods: We reviewed the blood cultores of children with cancer in five hospitals of Santiago, from 1994 at 1998. Results: During the study period, 707 agents were isolated. The most frequently isolated species or genus were coagulase negative Staphylococcus (43%), Staphylococcus aureus (16%), Escherichia coli (9%), Klebsiella spp. (8%), Pseudomonas spp. (5%) and Candida spp. (4%). Coagulase negative Staphylococcus was 55% resistant to meticilin and S. aureus was 44% resistant. Enterobacteriae had 15% resistance to gentamicin and amikacin, 2% to imipenem, 26% to ceftriaxone, 21% to cefotaxim and 20% to ceftazidim. Among non fermenting agents resistance was 6% for imipenem, 9% for amikacin 10% for ciprofloxacin, 19% for ceftazidim and 22% for cefoperazone. The resistance of Streptococcus spp. (non pneumoniae) to penicillin reached 50% and that of Enterococcus spp. was of 33%. Conclusions: Treatment for pediatric patients with cancer must be modified and new guidelines including more active medications for patients at risk for bacteremia, should be devised (Rev Méd Chile 2001; 129: 1297-1304)
author	Payá G,Ernesto Alvarez P,Ana María Avilés L,Carmen Cofré G,José Enríquez O,Nancy Salgado M,Carmen Santolaya de P,María Elena Silva G,Pamela Tordecilla C,Juan Varas P,Mónica Villarroel C,Milena Zubieta A,Marcela
author_facet	Payá G,Ernesto Alvarez P,Ana María Avilés L,Carmen Cofré G,José Enríquez O,Nancy Salgado M,Carmen Santolaya de P,María Elena Silva G,Pamela Tordecilla C,Juan Varas P,Mónica Villarroel C,Milena Zubieta A,Marcela
author_sort	Payá G,Ernesto
title	Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)
title_short	Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)
title_full	Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)
title_fullStr	Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)
title_full_unstemmed	Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)
title_sort	agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de santiago (1994-1998)
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100009
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Agentes causantes de infecciones del torrente circulatorio en niños con cáncer, en cinco hospitales de Santiago (1994-1998)

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