Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico
Resistant arterial hypertension is uncommon when there is good compliance to antihypertensive therapy and secondary causes have been ruled out. We report a 41 years old male that suffered hypertensive encephalopathy and received prophylactic anticonvulsant therapy showing progressive raise of arteri...
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Sociedad Médica de Santiago
2001
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oai:scielo:S0034-988720010011000142002-06-12Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínicoDowney C,PatricioFajuri N,AlejandroValdés S,Gloria Antihypertensive agents Carbamazepine Hypertension Phenytoin Resistant arterial hypertension is uncommon when there is good compliance to antihypertensive therapy and secondary causes have been ruled out. We report a 41 years old male that suffered hypertensive encephalopathy and received prophylactic anticonvulsant therapy showing progressive raise of arterial pressure levels. Renovascular hypertension, aldosteronism and pheochromocytoma were discarded and, in spite of combined use of antihypertensive drugs, he did not achieve normal blood pressure. When phenytoin was discontinued, blood pressure temporarily normalized. Carbamazepine was started and blood pressure raised again. lt fell when this medication was discontinued. Antiepileptic agents could induce drug metabolizing system and thus reduce the effects of antihypertensive medications. (Rev Méd Chile 2001; 129: 1325-7)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.11 20012001-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100014es10.4067/S0034-98872001001100014 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Antihypertensive agents Carbamazepine Hypertension Phenytoin |
spellingShingle |
Antihypertensive agents Carbamazepine Hypertension Phenytoin Downey C,Patricio Fajuri N,Alejandro Valdés S,Gloria Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico |
description |
Resistant arterial hypertension is uncommon when there is good compliance to antihypertensive therapy and secondary causes have been ruled out. We report a 41 years old male that suffered hypertensive encephalopathy and received prophylactic anticonvulsant therapy showing progressive raise of arterial pressure levels. Renovascular hypertension, aldosteronism and pheochromocytoma were discarded and, in spite of combined use of antihypertensive drugs, he did not achieve normal blood pressure. When phenytoin was discontinued, blood pressure temporarily normalized. Carbamazepine was started and blood pressure raised again. lt fell when this medication was discontinued. Antiepileptic agents could induce drug metabolizing system and thus reduce the effects of antihypertensive medications. (Rev Méd Chile 2001; 129: 1325-7) |
author |
Downey C,Patricio Fajuri N,Alejandro Valdés S,Gloria |
author_facet |
Downey C,Patricio Fajuri N,Alejandro Valdés S,Gloria |
author_sort |
Downey C,Patricio |
title |
Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico |
title_short |
Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico |
title_full |
Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico |
title_fullStr |
Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico |
title_full_unstemmed |
Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico |
title_sort |
hipertensión arterial refractaria y uso de drogas anticonvulsivantes: caso clínico |
publisher |
Sociedad Médica de Santiago |
publishDate |
2001 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100014 |
work_keys_str_mv |
AT downeycpatricio hipertensionarterialrefractariayusodedrogasanticonvulsivantescasoclinico AT fajurinalejandro hipertensionarterialrefractariayusodedrogasanticonvulsivantescasoclinico AT valdessgloria hipertensionarterialrefractariayusodedrogasanticonvulsivantescasoclinico |
_version_ |
1718436002022817792 |