Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico

Resistant arterial hypertension is uncommon when there is good compliance to antihypertensive therapy and secondary causes have been ruled out. We report a 41 years old male that suffered hypertensive encephalopathy and received prophylactic anticonvulsant therapy showing progressive raise of arteri...

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Autores principales: Downey C,Patricio, Fajuri N,Alejandro, Valdés S,Gloria
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2001
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100014
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spelling oai:scielo:S0034-988720010011000142002-06-12Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínicoDowney C,PatricioFajuri N,AlejandroValdés S,Gloria Antihypertensive agents Carbamazepine Hypertension Phenytoin Resistant arterial hypertension is uncommon when there is good compliance to antihypertensive therapy and secondary causes have been ruled out. We report a 41 years old male that suffered hypertensive encephalopathy and received prophylactic anticonvulsant therapy showing progressive raise of arterial pressure levels. Renovascular hypertension, aldosteronism and pheochromocytoma were discarded and, in spite of combined use of antihypertensive drugs, he did not achieve normal blood pressure. When phenytoin was discontinued, blood pressure temporarily normalized. Carbamazepine was started and blood pressure raised again. lt fell when this medication was discontinued. Antiepileptic agents could induce drug metabolizing system and thus reduce the effects of antihypertensive medications. (Rev Méd Chile 2001; 129: 1325-7)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.11 20012001-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100014es10.4067/S0034-98872001001100014
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Antihypertensive agents
Carbamazepine
Hypertension
Phenytoin
spellingShingle Antihypertensive agents
Carbamazepine
Hypertension
Phenytoin
Downey C,Patricio
Fajuri N,Alejandro
Valdés S,Gloria
Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico
description Resistant arterial hypertension is uncommon when there is good compliance to antihypertensive therapy and secondary causes have been ruled out. We report a 41 years old male that suffered hypertensive encephalopathy and received prophylactic anticonvulsant therapy showing progressive raise of arterial pressure levels. Renovascular hypertension, aldosteronism and pheochromocytoma were discarded and, in spite of combined use of antihypertensive drugs, he did not achieve normal blood pressure. When phenytoin was discontinued, blood pressure temporarily normalized. Carbamazepine was started and blood pressure raised again. lt fell when this medication was discontinued. Antiepileptic agents could induce drug metabolizing system and thus reduce the effects of antihypertensive medications. (Rev Méd Chile 2001; 129: 1325-7)
author Downey C,Patricio
Fajuri N,Alejandro
Valdés S,Gloria
author_facet Downey C,Patricio
Fajuri N,Alejandro
Valdés S,Gloria
author_sort Downey C,Patricio
title Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico
title_short Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico
title_full Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico
title_fullStr Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico
title_full_unstemmed Hipertensión arterial refractaria y uso de drogas anticonvulsivantes: Caso clínico
title_sort hipertensión arterial refractaria y uso de drogas anticonvulsivantes: caso clínico
publisher Sociedad Médica de Santiago
publishDate 2001
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100014
work_keys_str_mv AT downeycpatricio hipertensionarterialrefractariayusodedrogasanticonvulsivantescasoclinico
AT fajurinalejandro hipertensionarterialrefractariayusodedrogasanticonvulsivantescasoclinico
AT valdessgloria hipertensionarterialrefractariayusodedrogasanticonvulsivantescasoclinico
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