Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo

The risk for invasive bacterial infection (IBI) in cancer pediatric patients with febrile neutropenia, is variable. Clinicians worldwide are increasingly considering selective strategies for children at low risk for IBI, including shortened antimicrobial course, early hospital discharge, oral antimi...

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Autor principal:	Santolaya de P,María Elena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2001
Materias:	Anti-infective agents Neoplasms Neutropenia Models, Theoretical
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001200012
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spelling	oai:scielo:S0034-988720010012000122005-11-22Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivoSantolaya de P,María Elena Anti-infective agents Neoplasms Neutropenia Models, Theoretical The risk for invasive bacterial infection (IBI) in cancer pediatric patients with febrile neutropenia, is variable. Clinicians worldwide are increasingly considering selective strategies for children at low risk for IBI, including shortened antimicrobial course, early hospital discharge, oral antimicrobial treatment, and management as outpatients. These strategies would significantly benefit these children and health care systems. The critical issue is to identify the most reliable risk factors useful for selection of those individuals who are at low risk for IBI. In Chile, during the past 10 years, a group of physicians from the Subcommittee of Infectious Diseases of the National Child Program of Antineoplastic Drugs and the University of Chile have worked to develop more selective strategies for pediatric patients with cancer, fever and neutropenia. During 1996-1997 we identified risk factors of IBI in a group of 447 febrile neutropenic episodes. During 1999-2000 we validated these risk factors in a prospective study that included 263 febrile neutropenic episodes. A model of risk prediction was developed and is currently being evaluated for the selection of low risk patients who are treated as inpatients for 24 hours, followed by outpatient treatment (Rev Méd Chile 2001; 129: 1449-1454)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.12 20012001-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001200012es10.4067/S0034-98872001001200012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Anti-infective agents Neoplasms Neutropenia Models, Theoretical
spellingShingle	Anti-infective agents Neoplasms Neutropenia Models, Theoretical Santolaya de P,María Elena Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo
description	The risk for invasive bacterial infection (IBI) in cancer pediatric patients with febrile neutropenia, is variable. Clinicians worldwide are increasingly considering selective strategies for children at low risk for IBI, including shortened antimicrobial course, early hospital discharge, oral antimicrobial treatment, and management as outpatients. These strategies would significantly benefit these children and health care systems. The critical issue is to identify the most reliable risk factors useful for selection of those individuals who are at low risk for IBI. In Chile, during the past 10 years, a group of physicians from the Subcommittee of Infectious Diseases of the National Child Program of Antineoplastic Drugs and the University of Chile have worked to develop more selective strategies for pediatric patients with cancer, fever and neutropenia. During 1996-1997 we identified risk factors of IBI in a group of 447 febrile neutropenic episodes. During 1999-2000 we validated these risk factors in a prospective study that included 263 febrile neutropenic episodes. A model of risk prediction was developed and is currently being evaluated for the selection of low risk patients who are treated as inpatients for 24 hours, followed by outpatient treatment (Rev Méd Chile 2001; 129: 1449-1454)
author	Santolaya de P,María Elena
author_facet	Santolaya de P,María Elena
author_sort	Santolaya de P,María Elena
title	Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo
title_short	Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo
title_full	Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo
title_fullStr	Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo
title_full_unstemmed	Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo
title_sort	neutropenia febril en el niño con cáncer: conceptos actuales sobre criterios de riesgo y manejo selectivo
publisher	Sociedad Médica de Santiago
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001200012
work_keys_str_mv	AT santolayadepmariaelena neutropeniafebrilenelninoconcancerconceptosactualessobrecriteriosderiesgoymanejoselectivo
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Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo

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