Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal

Background: The pathophysiological hallmark of the hepatorenal syndrome (HRS) is renal vasoconstriction. Doppler ultrasonography can be used to assess the vascular resistance in small renal intraparenchymal vessels through analysis of the Doppler waveform by a parameter termed Resistive Index (RI)....

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Autores principales: Bardi S,Alberto, Sapunar P,Jorge, Oksenberg R,Dan, Poniachik T,Jaime, Fernández A,Manuel, Paolinelli G,Paola, Orozco S,René, Biagini A,Leandro
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200007
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spelling oai:scielo:S0034-988720020002000072014-08-20Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenalBardi S,AlbertoSapunar P,JorgeOksenberg R,DanPoniachik T,JaimeFernández A,ManuelPaolinelli G,PaolaOrozco S,RenéBiagini A,Leandro Ascites Hepatorenal syndrome Liver cirrhosis Ultrasonography, Doppler, color Ultrasonography, Doppler, pulsed Background: The pathophysiological hallmark of the hepatorenal syndrome (HRS) is renal vasoconstriction. Doppler ultrasonography can be used to assess the vascular resistance in small renal intraparenchymal vessels through analysis of the Doppler waveform by a parameter termed Resistive Index (RI). We postulated that the RI could be important for the diagnosis and prognosis of HRS. Aims: to assess the RI in cirrhotic patients with ascites, with and without HRS. Patients and methods: We studied 48 cirrhotics with ascites, of whom 12 were with and 36 without HRS and other 23 were normal subjects. We measured the intrarenal arterial RI (Resistive index = Peak systolic velocity - Minimum diastolic velocity/Peak systolic velocity) with color Doppler ultrasonography after visualization of interlobular or arcuate arteries. It was considered abnormal when higher than 0.70. Results: The RI values, mean and SD) were: normal subjects: 0.58 ± 0.05, cirrhotics with ascites: 0.65 ± 0.05 and cirrhotics with ascites and HRS: 0.78 ± 0.11. Patients with HRS had significantly higher values than those without HRS (p < 0.001). The Relative Risk of developing the HRS in patients with a RI &#8805; 0.70 were 3.32 (CI 95% = 1.79 - 6.2) Conclusions: The RI was useful in patients with cirrhosis and ascites for the prognosis of HRS and could suggest diagnosis of HRS with values of 0.78 or higher, if other clinical conditions that produce renal vasoconstriction are excluded (Rev Méd Chile 2002; 130: 173-80)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.2 20022002-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200007es10.4067/S0034-98872002000200007
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Ascites
Hepatorenal syndrome
Liver cirrhosis
Ultrasonography, Doppler, color
Ultrasonography, Doppler, pulsed
spellingShingle Ascites
Hepatorenal syndrome
Liver cirrhosis
Ultrasonography, Doppler, color
Ultrasonography, Doppler, pulsed
Bardi S,Alberto
Sapunar P,Jorge
Oksenberg R,Dan
Poniachik T,Jaime
Fernández A,Manuel
Paolinelli G,Paola
Orozco S,René
Biagini A,Leandro
Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal
description Background: The pathophysiological hallmark of the hepatorenal syndrome (HRS) is renal vasoconstriction. Doppler ultrasonography can be used to assess the vascular resistance in small renal intraparenchymal vessels through analysis of the Doppler waveform by a parameter termed Resistive Index (RI). We postulated that the RI could be important for the diagnosis and prognosis of HRS. Aims: to assess the RI in cirrhotic patients with ascites, with and without HRS. Patients and methods: We studied 48 cirrhotics with ascites, of whom 12 were with and 36 without HRS and other 23 were normal subjects. We measured the intrarenal arterial RI (Resistive index = Peak systolic velocity - Minimum diastolic velocity/Peak systolic velocity) with color Doppler ultrasonography after visualization of interlobular or arcuate arteries. It was considered abnormal when higher than 0.70. Results: The RI values, mean and SD) were: normal subjects: 0.58 ± 0.05, cirrhotics with ascites: 0.65 ± 0.05 and cirrhotics with ascites and HRS: 0.78 ± 0.11. Patients with HRS had significantly higher values than those without HRS (p < 0.001). The Relative Risk of developing the HRS in patients with a RI &#8805; 0.70 were 3.32 (CI 95% = 1.79 - 6.2) Conclusions: The RI was useful in patients with cirrhosis and ascites for the prognosis of HRS and could suggest diagnosis of HRS with values of 0.78 or higher, if other clinical conditions that produce renal vasoconstriction are excluded (Rev Méd Chile 2002; 130: 173-80)
author Bardi S,Alberto
Sapunar P,Jorge
Oksenberg R,Dan
Poniachik T,Jaime
Fernández A,Manuel
Paolinelli G,Paola
Orozco S,René
Biagini A,Leandro
author_facet Bardi S,Alberto
Sapunar P,Jorge
Oksenberg R,Dan
Poniachik T,Jaime
Fernández A,Manuel
Paolinelli G,Paola
Orozco S,René
Biagini A,Leandro
author_sort Bardi S,Alberto
title Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal
title_short Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal
title_full Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal
title_fullStr Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal
title_full_unstemmed Ecotomografía Doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal
title_sort ecotomografía doppler arterial intrarrenal en pacientes cirróticos con ascitis, con y sin síndrome hepatorrenal
publisher Sociedad Médica de Santiago
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200007
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AT orozcosrene ecotomografiadopplerarterialintrarrenalenpacientescirroticosconascitisconysinsindromehepatorrenal
AT biaginialeandro ecotomografiadopplerarterialintrarrenalenpacientescirroticosconascitisconysinsindromehepatorrenal
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