Fascitis eosinofílica: experiencia en tres casos

Eosinophilic fasciitis (EF) is a scleroderma-like disease of unknown etiology characterized by cutaneous swelling and induration that affects predominantly the extremities, elevated immune globulins, and peripheral eosinophilia. We report three patients with clinical, laboratory and pathologic chara...

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Autores principales: Velásquez G,Ximena, Gutiérrez T,Miguel A, Rosenberg G,Helmar, Figueroa E,Fernando, Bronstein A,Eduardo, Jacobelli G,Sergio
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200011
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spelling oai:scielo:S0034-988720020002000112014-08-20Fascitis eosinofílica: experiencia en tres casosVelásquez G,XimenaGutiérrez T,Miguel ARosenberg G,HelmarFigueroa E,FernandoBronstein A,EduardoJacobelli G,Sergio Eosinophilic fasciitis Fasciitis Scleroderma, circumscribed Sclerodermat systemic Eosinophilic fasciitis (EF) is a scleroderma-like disease of unknown etiology characterized by cutaneous swelling and induration that affects predominantly the extremities, elevated immune globulins, and peripheral eosinophilia. We report three patients with clinical, laboratory and pathologic characteristics of EF. The main symptoms were cutaneous and included "peau d' orange", groove signs and induration of the affected extremities. Two patients had skin changes after exercising and one had a hypothyroidism. None had extra-cutaneous manifestations. All patients had peripheral eosinophilia. Pathologic findings were thickening and inflammation of the fascia and normal epidermis. Only one patient was treated with prednisone 30 mg daily and showed only moderate improvement. There is no follow up information about the other two cases. EF is a rare disorder classified at times as scleroderma variants. However, its clinical picture, capillary microscopy findings, pathology and prognosis differentiate it from systemic sclerosis. (Rev Méd Chile 2002; 130: 209-14)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.2 20022002-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200011es10.4067/S0034-98872002000200011
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Eosinophilic fasciitis
Fasciitis
Scleroderma, circumscribed
Sclerodermat systemic
spellingShingle Eosinophilic fasciitis
Fasciitis
Scleroderma, circumscribed
Sclerodermat systemic
Velásquez G,Ximena
Gutiérrez T,Miguel A
Rosenberg G,Helmar
Figueroa E,Fernando
Bronstein A,Eduardo
Jacobelli G,Sergio
Fascitis eosinofílica: experiencia en tres casos
description Eosinophilic fasciitis (EF) is a scleroderma-like disease of unknown etiology characterized by cutaneous swelling and induration that affects predominantly the extremities, elevated immune globulins, and peripheral eosinophilia. We report three patients with clinical, laboratory and pathologic characteristics of EF. The main symptoms were cutaneous and included "peau d' orange", groove signs and induration of the affected extremities. Two patients had skin changes after exercising and one had a hypothyroidism. None had extra-cutaneous manifestations. All patients had peripheral eosinophilia. Pathologic findings were thickening and inflammation of the fascia and normal epidermis. Only one patient was treated with prednisone 30 mg daily and showed only moderate improvement. There is no follow up information about the other two cases. EF is a rare disorder classified at times as scleroderma variants. However, its clinical picture, capillary microscopy findings, pathology and prognosis differentiate it from systemic sclerosis. (Rev Méd Chile 2002; 130: 209-14)
author Velásquez G,Ximena
Gutiérrez T,Miguel A
Rosenberg G,Helmar
Figueroa E,Fernando
Bronstein A,Eduardo
Jacobelli G,Sergio
author_facet Velásquez G,Ximena
Gutiérrez T,Miguel A
Rosenberg G,Helmar
Figueroa E,Fernando
Bronstein A,Eduardo
Jacobelli G,Sergio
author_sort Velásquez G,Ximena
title Fascitis eosinofílica: experiencia en tres casos
title_short Fascitis eosinofílica: experiencia en tres casos
title_full Fascitis eosinofílica: experiencia en tres casos
title_fullStr Fascitis eosinofílica: experiencia en tres casos
title_full_unstemmed Fascitis eosinofílica: experiencia en tres casos
title_sort fascitis eosinofílica: experiencia en tres casos
publisher Sociedad Médica de Santiago
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200011
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AT rosenbergghelmar fascitiseosinofilicaexperienciaentrescasos
AT figueroaefernando fascitiseosinofilicaexperienciaentrescasos
AT bronsteinaeduardo fascitiseosinofilicaexperienciaentrescasos
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