Macroglosia y amiloidosis oculta

Amyloidosis is a rare disease characterized by the pathological deposit of extracellular proteins in organs or tissues. We report a 78 years old female with a history of euthyroid goiter and carpal syndrome, that presented complaining of weight loss and the sensation of a big and rough tongue. On ph...

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Autores principales: Moroni L,Ana María, Benavides M,Alicia, Retamal E,Yasmina
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200012
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spelling oai:scielo:S0034-988720020002000122014-08-20Macroglosia y amiloidosis ocultaMoroni L,Ana MaríaBenavides M,AliciaRetamal E,Yasmina Amyloidosis Macroglossia Melphalan Prednisone Amyloidosis is a rare disease characterized by the pathological deposit of extracellular proteins in organs or tissues. We report a 78 years old female with a history of euthyroid goiter and carpal syndrome, that presented complaining of weight loss and the sensation of a big and rough tongue. On physical examination, macroglossia and white nodules of 1.5 cm diameter in the mucosa of the mouth, were observed. The pathological examination of these nodules disclosed amyloid infiltration. A bone marrow biopsy showed plasma cell infiltration. The patient was treated with melphalan and prednisone, but she deteriorated progressively and died 14 months after the diagnosis. (Rev Méd Chile 2002; 130: 215-8)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.2 20022002-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200012es10.4067/S0034-98872002000200012
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Amyloidosis
Macroglossia
Melphalan
Prednisone
spellingShingle Amyloidosis
Macroglossia
Melphalan
Prednisone
Moroni L,Ana María
Benavides M,Alicia
Retamal E,Yasmina
Macroglosia y amiloidosis oculta
description Amyloidosis is a rare disease characterized by the pathological deposit of extracellular proteins in organs or tissues. We report a 78 years old female with a history of euthyroid goiter and carpal syndrome, that presented complaining of weight loss and the sensation of a big and rough tongue. On physical examination, macroglossia and white nodules of 1.5 cm diameter in the mucosa of the mouth, were observed. The pathological examination of these nodules disclosed amyloid infiltration. A bone marrow biopsy showed plasma cell infiltration. The patient was treated with melphalan and prednisone, but she deteriorated progressively and died 14 months after the diagnosis. (Rev Méd Chile 2002; 130: 215-8)
author Moroni L,Ana María
Benavides M,Alicia
Retamal E,Yasmina
author_facet Moroni L,Ana María
Benavides M,Alicia
Retamal E,Yasmina
author_sort Moroni L,Ana María
title Macroglosia y amiloidosis oculta
title_short Macroglosia y amiloidosis oculta
title_full Macroglosia y amiloidosis oculta
title_fullStr Macroglosia y amiloidosis oculta
title_full_unstemmed Macroglosia y amiloidosis oculta
title_sort macroglosia y amiloidosis oculta
publisher Sociedad Médica de Santiago
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000200012
work_keys_str_mv AT moronilanamaria macroglosiayamiloidosisoculta
AT benavidesmalicia macroglosiayamiloidosisoculta
AT retamaleyasmina macroglosiayamiloidosisoculta
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