Elementos morfológicos pronósticos en el cáncer de la vesícula biliar

Background: The exact survival rates and prognostic factors of gallbladder cancer are still incompletely known. Aim: To report the actuarial survival of patients with gallbladder cancer. Material and methods: Six hundred thirty seven women, aged 59 years old as a mean and 108 men, aged 64 years old...

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Autores principales: Roa E,Iván, de Aretxabala U,Xabier, Araya O,Juan C, Villaseca H,Miguel, Roa S,Juan, Ibacache S,TM Gilda, Burgos S,Luis, Muñoz N,Sergio
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000400005
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spelling oai:scielo:S0034-988720020004000052003-01-24Elementos morfológicos pronósticos en el cáncer de la vesícula biliarRoa E,Ivánde Aretxabala U,XabierAraya O,Juan CVillaseca H,MiguelRoa S,JuanIbacache S,TM GildaBurgos S,LuisMuñoz N,Sergio Cholecystectomy Gallbladder neoplasms Survival analysis Background: The exact survival rates and prognostic factors of gallbladder cancer are still incompletely known. Aim: To report the actuarial survival of patients with gallbladder cancer. Material and methods: Six hundred thirty seven women, aged 59 years old as a mean and 108 men, aged 64 years old as a mean, with gallbladder cancer are reported. Patients were followed for up to 150 months. Results: Two hundred twenty four patients had an early and 521 had an advanced carcinoma. Overall survival was 38% at ten years. Sex or ethnic origin did not influence survival. Early tumors had a 92% survival at 10 years whereas the survival of advanced tumors was 16% at 5 years. Subserous tumors had a 5 years survival of 32% whereas serous tumors had a 5 years survival of 11%. Well-differentiated advanced tumors had a significantly better survival than moderately or poorly differentiated tumors. Vascular or lymphatic infiltration was also associated to a lower survival. All patients with advanced tumors and vascular infiltration died before 5 years. Conclusions: Tumor infiltration and differentiation degree were the most important prognostic independent factors in gallbladder cancer (Rev Méd Chile 2002; 130: 387-395)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.4 20022002-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000400005es10.4067/S0034-98872002000400005
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Cholecystectomy
Gallbladder neoplasms
Survival analysis
spellingShingle Cholecystectomy
Gallbladder neoplasms
Survival analysis
Roa E,Iván
de Aretxabala U,Xabier
Araya O,Juan C
Villaseca H,Miguel
Roa S,Juan
Ibacache S,TM Gilda
Burgos S,Luis
Muñoz N,Sergio
Elementos morfológicos pronósticos en el cáncer de la vesícula biliar
description Background: The exact survival rates and prognostic factors of gallbladder cancer are still incompletely known. Aim: To report the actuarial survival of patients with gallbladder cancer. Material and methods: Six hundred thirty seven women, aged 59 years old as a mean and 108 men, aged 64 years old as a mean, with gallbladder cancer are reported. Patients were followed for up to 150 months. Results: Two hundred twenty four patients had an early and 521 had an advanced carcinoma. Overall survival was 38% at ten years. Sex or ethnic origin did not influence survival. Early tumors had a 92% survival at 10 years whereas the survival of advanced tumors was 16% at 5 years. Subserous tumors had a 5 years survival of 32% whereas serous tumors had a 5 years survival of 11%. Well-differentiated advanced tumors had a significantly better survival than moderately or poorly differentiated tumors. Vascular or lymphatic infiltration was also associated to a lower survival. All patients with advanced tumors and vascular infiltration died before 5 years. Conclusions: Tumor infiltration and differentiation degree were the most important prognostic independent factors in gallbladder cancer (Rev Méd Chile 2002; 130: 387-395)
author Roa E,Iván
de Aretxabala U,Xabier
Araya O,Juan C
Villaseca H,Miguel
Roa S,Juan
Ibacache S,TM Gilda
Burgos S,Luis
Muñoz N,Sergio
author_facet Roa E,Iván
de Aretxabala U,Xabier
Araya O,Juan C
Villaseca H,Miguel
Roa S,Juan
Ibacache S,TM Gilda
Burgos S,Luis
Muñoz N,Sergio
author_sort Roa E,Iván
title Elementos morfológicos pronósticos en el cáncer de la vesícula biliar
title_short Elementos morfológicos pronósticos en el cáncer de la vesícula biliar
title_full Elementos morfológicos pronósticos en el cáncer de la vesícula biliar
title_fullStr Elementos morfológicos pronósticos en el cáncer de la vesícula biliar
title_full_unstemmed Elementos morfológicos pronósticos en el cáncer de la vesícula biliar
title_sort elementos morfológicos pronósticos en el cáncer de la vesícula biliar
publisher Sociedad Médica de Santiago
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000400005
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