Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en Chile

Background. Chilean women have one of the highest mortality rates from gallstone disease in the world. There is no primary prevention for the disease and the benefits of prophylactic cholecystectomy in high risk groups have not been studied. Aim: To analyze the cost and effectiveness of a screening...

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Autores principales: Puschel I,Klaus, Sullivan,Sean, Montero L,Joaquín, Thompson,Beti, Díaz F,Alfonso
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000400014
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spelling oai:scielo:S0034-988720020004000142003-01-24Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en ChilePuschel I,KlausSullivan,SeanMontero L,JoaquínThompson,BetiDíaz F,Alfonso Cholecystectomy Cholelithiasis Gallbladder diseases Background. Chilean women have one of the highest mortality rates from gallstone disease in the world. There is no primary prevention for the disease and the benefits of prophylactic cholecystectomy in high risk groups have not been studied. Aim: To analyze the cost and effectiveness of a screening program for gallbladder disease in the Chilean women population. Methods. A decision analytic model is used to compare lifetime cost and effectiveness of standard care with three screening strategies. The first two strategies consider "universal ultrasound screening" for all women 40 years old and laparoscopic cholecystectomy for those with gallstones ("elective intervention") or with calculous ≥3 cm ("high risk intervention"). The third strategy is based on "selective screening" for obese women. Results. The lifetime probability of a 40 years old Chilean woman of dying from gallbladder disease is reduced by 70% in the universal screening/elective intervention, by 63% in the high risk intervention and by 18% in the selective screening strategy. Her lifetime expectancy increases by 5.25, 4.64 and 1.24 months respectively. The incremental cost-effectiveness ratio of each screening strategy is US$ 180, US$ 147 and US$ 481 respectively. Conclusion. A screening program for gallbladder disease in a high risk population achieves significant benefits at a low incremental cost and acceptable cost-effectivenessinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.4 20022002-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000400014es10.4067/S0034-98872002000400014
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Cholecystectomy
Cholelithiasis
Gallbladder diseases
spellingShingle Cholecystectomy
Cholelithiasis
Gallbladder diseases
Puschel I,Klaus
Sullivan,Sean
Montero L,Joaquín
Thompson,Beti
Díaz F,Alfonso
Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en Chile
description Background. Chilean women have one of the highest mortality rates from gallstone disease in the world. There is no primary prevention for the disease and the benefits of prophylactic cholecystectomy in high risk groups have not been studied. Aim: To analyze the cost and effectiveness of a screening program for gallbladder disease in the Chilean women population. Methods. A decision analytic model is used to compare lifetime cost and effectiveness of standard care with three screening strategies. The first two strategies consider "universal ultrasound screening" for all women 40 years old and laparoscopic cholecystectomy for those with gallstones ("elective intervention") or with calculous ≥3 cm ("high risk intervention"). The third strategy is based on "selective screening" for obese women. Results. The lifetime probability of a 40 years old Chilean woman of dying from gallbladder disease is reduced by 70% in the universal screening/elective intervention, by 63% in the high risk intervention and by 18% in the selective screening strategy. Her lifetime expectancy increases by 5.25, 4.64 and 1.24 months respectively. The incremental cost-effectiveness ratio of each screening strategy is US$ 180, US$ 147 and US$ 481 respectively. Conclusion. A screening program for gallbladder disease in a high risk population achieves significant benefits at a low incremental cost and acceptable cost-effectiveness
author Puschel I,Klaus
Sullivan,Sean
Montero L,Joaquín
Thompson,Beti
Díaz F,Alfonso
author_facet Puschel I,Klaus
Sullivan,Sean
Montero L,Joaquín
Thompson,Beti
Díaz F,Alfonso
author_sort Puschel I,Klaus
title Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en Chile
title_short Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en Chile
title_full Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en Chile
title_fullStr Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en Chile
title_full_unstemmed Análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en Chile
title_sort análisis de costo-efectividad de un programa preventivo de enfermedad vesicular en chile
publisher Sociedad Médica de Santiago
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000400014
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