Corrección de la anemia en hemodiálisis, efecto del fierro intravenoso sin eritropoyetina

Background: In the last two decades, the use of erythropoietin for the correction of anemia in hemodialysis patients has been recommended. In Chile, only 10% of hemodialysis patients use erythropoietin, therefore, the correction of iron deficiency must be optimized. Aim: To report the effects of int...

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Autores principales: Alvo A,Miriam, Elgueta S,Leticia, Aragón V,Henry, Cotera F,Alejandro
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000800004
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Sumario:Background: In the last two decades, the use of erythropoietin for the correction of anemia in hemodialysis patients has been recommended. In Chile, only 10% of hemodialysis patients use erythropoietin, therefore, the correction of iron deficiency must be optimized. Aim: To report the effects of intravenous iron without erythropoietin in the management of anemia in hemodialysis patients. Material and methods: Retrospective analysis of 42 patients that received intravenous ferrous sacarate in doses of 100 mg/week during 5 weeks and 100 mg bimonthly during six months. These patients did not receive erythropoietin. Results. Thirty six patients had iron deficiency. Basal ferritin was 137±22 µg/l and increased to 321±28 µg/l after treatment. Packed red cell volume increased from 24±2% to 29±3%. No adverse effects were reported. Conclusions: Iron deficiency is frequent in hemodialyzed patients. Intravenous iron is safe and effective in the treatment of iron deficiency in these patients (Rev Méd Chile 2002; 130: 865-8)