Leucemia mieloide crónica en hemofilia B: Report of one case

A known hemophiliac B male (blood coagulation factor IX level of 15%), HIV negative, in whom a Philadelphia chromosome positive chronic myeloid leukemia developed at the age of 29 years, is presented. The leukemia was diagnosed after an upper digestive tract bleeding, due to a duodenal ulcer. Two ye...

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Autor principal:	Larraín A,Camilo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2002
Materias:	Busulfan Hemophilia B Leukemia, myeloid, Philadelphia-positive
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000800009
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spelling	oai:scielo:S0034-988720020008000092014-08-21Leucemia mieloide crónica en hemofilia B: Report of one caseLarraín A,Camilo Busulfan Hemophilia B Leukemia, myeloid, Philadelphia-positive A known hemophiliac B male (blood coagulation factor IX level of 15%), HIV negative, in whom a Philadelphia chromosome positive chronic myeloid leukemia developed at the age of 29 years, is presented. The leukemia was diagnosed after an upper digestive tract bleeding, due to a duodenal ulcer. Two years elapsed between the diagnosis of leukemia and the start of busulfan therapy. During that period and after the start of treatment, the hemorrhagic tendency did not increase. The follow up of the patient was almost 8 years, with favorable clinical response to busulfan therapy. The patient survived more than twice the average survival of chronic myeloid leukemia patients treated with busulfan. A reciprocal influence between chronic myeloid leukemia and hemophilia appears illustrated by this case report (Rev Méd Chile 2002; 130: 897-900)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.8 20022002-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000800009es10.4067/S0034-98872002000800009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Busulfan Hemophilia B Leukemia, myeloid, Philadelphia-positive
spellingShingle	Busulfan Hemophilia B Leukemia, myeloid, Philadelphia-positive Larraín A,Camilo Leucemia mieloide crónica en hemofilia B: Report of one case
description	A known hemophiliac B male (blood coagulation factor IX level of 15%), HIV negative, in whom a Philadelphia chromosome positive chronic myeloid leukemia developed at the age of 29 years, is presented. The leukemia was diagnosed after an upper digestive tract bleeding, due to a duodenal ulcer. Two years elapsed between the diagnosis of leukemia and the start of busulfan therapy. During that period and after the start of treatment, the hemorrhagic tendency did not increase. The follow up of the patient was almost 8 years, with favorable clinical response to busulfan therapy. The patient survived more than twice the average survival of chronic myeloid leukemia patients treated with busulfan. A reciprocal influence between chronic myeloid leukemia and hemophilia appears illustrated by this case report (Rev Méd Chile 2002; 130: 897-900)
author	Larraín A,Camilo
author_facet	Larraín A,Camilo
author_sort	Larraín A,Camilo
title	Leucemia mieloide crónica en hemofilia B: Report of one case
title_short	Leucemia mieloide crónica en hemofilia B: Report of one case
title_full	Leucemia mieloide crónica en hemofilia B: Report of one case
title_fullStr	Leucemia mieloide crónica en hemofilia B: Report of one case
title_full_unstemmed	Leucemia mieloide crónica en hemofilia B: Report of one case
title_sort	leucemia mieloide crónica en hemofilia b: report of one case
publisher	Sociedad Médica de Santiago
publishDate	2002
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000800009
work_keys_str_mv	AT larrainacamilo leucemiamieloidecronicaenhemofiliabreportofonecase
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Leucemia mieloide crónica en hemofilia B: Report of one case

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