Síndrome de Turner: Crecimiento y descripción clínica en 83 niñas chilenas
Background: Short stature is the main feature of patients with Turner's syndrome. There is limited information regarding the spontaneous growth of these patients in Chile. Aim: To develop a specific growth chart for Chilean patients with Turner's syndrome. Material and methods: We retrospe...
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| Autores principales: | , , , , , , |
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| Lenguaje: | Spanish / Castilian |
| Publicado: |
Sociedad Médica de Santiago
2002
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| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000900003 |
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| Sumario: | Background: Short stature is the main feature of patients with Turner's syndrome. There is limited information regarding the spontaneous growth of these patients in Chile. Aim: To develop a specific growth chart for Chilean patients with Turner's syndrome. Material and methods: We retrospectively analyzed 668 height measurements from 85 Chilean girls, born after 1968, with 45XO karyotype (minimum 15%), and without an Y chromosome fragment. Patients with hormonal therapy, such as growth hormone or estrogen, except thyroid hormone replacement, were excluded. Results: The karyotypes were 60% 45XO, 25% 45XO, 46XX, and 15% other complex mosaics. The birth length was 46.8 ± 2.1 cm. The final height of our patients was 138,20 ± 7,0 cm. Conclusions: The final height achieved by our patients, is similar to Argentinian and Japanese patients, but is below the mean stature reported for Scandinavian and Northamerican patients who achieve a mean adult height of approximately 147 and 142 cm respectively. The birth length is also lower than that reported in those studies (Rev Méd Chile 2002; 130: 977-84). |
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