Efecto de la midodrina en la hipotensión sintomática en hemodiálisis

Background: Hypotension occurs in 20% of hemodialysis procedures. Aim: To study the effects of midodrine on hypotension during hemodialysis. Patients and methods: Ten patients on chronic hemodialysis and with a history of hypotension during the procedure, were studied. They received midodrine 10 mg...

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Autores principales: Cotera F,Alejandro, Alvo A,Miriam, Sanhueza V,María Eugenia, Elgueta S,Leticia, Gormaz B,Juan Pablo, Ibáñez B,Carlos, Cuadra C,Cristián
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000900007
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spelling oai:scielo:S0034-988720020009000072005-11-29Efecto de la midodrina en la hipotensión sintomática en hemodiálisisCotera F,AlejandroAlvo A,MiriamSanhueza V,María EugeniaElgueta S,LeticiaGormaz B,Juan PabloIbáñez B,CarlosCuadra C,Cristián Hemodialysis Hypotension orthostatic Midodrine Background: Hypotension occurs in 20% of hemodialysis procedures. Aim: To study the effects of midodrine on hypotension during hemodialysis. Patients and methods: Ten patients on chronic hemodialysis and with a history of hypotension during the procedure, were studied. They received midodrine 10 mg per os or placebo during 5 dialytic procedures each, in a double blind cross over design. Results: Blood pressure levels prior to dialysis were similar during the midodrine or placebo administration periods. During dialysis, systolic blood pressure fell 19.3±28 mmHg with midodrine and 23.4±28 mmHg with placebo. Diastolic blood pressure fell 7.3±11.5 mmHg with midodrine and 11.1±12 mmHg with placebo. The reduction in median arterial pressure was also less pronounced with midodrine. Conclusions: Midodrine lessens the fall in arterial pressure during hemodialysis, in patients with symptomatic hypotension (Rev Méd Chile 2002; 130: 1009-13)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.9 20022002-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000900007es10.4067/S0034-98872002000900007
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Hemodialysis
Hypotension
orthostatic
Midodrine
spellingShingle Hemodialysis
Hypotension
orthostatic
Midodrine
Cotera F,Alejandro
Alvo A,Miriam
Sanhueza V,María Eugenia
Elgueta S,Leticia
Gormaz B,Juan Pablo
Ibáñez B,Carlos
Cuadra C,Cristián
Efecto de la midodrina en la hipotensión sintomática en hemodiálisis
description Background: Hypotension occurs in 20% of hemodialysis procedures. Aim: To study the effects of midodrine on hypotension during hemodialysis. Patients and methods: Ten patients on chronic hemodialysis and with a history of hypotension during the procedure, were studied. They received midodrine 10 mg per os or placebo during 5 dialytic procedures each, in a double blind cross over design. Results: Blood pressure levels prior to dialysis were similar during the midodrine or placebo administration periods. During dialysis, systolic blood pressure fell 19.3±28 mmHg with midodrine and 23.4±28 mmHg with placebo. Diastolic blood pressure fell 7.3±11.5 mmHg with midodrine and 11.1±12 mmHg with placebo. The reduction in median arterial pressure was also less pronounced with midodrine. Conclusions: Midodrine lessens the fall in arterial pressure during hemodialysis, in patients with symptomatic hypotension (Rev Méd Chile 2002; 130: 1009-13)
author Cotera F,Alejandro
Alvo A,Miriam
Sanhueza V,María Eugenia
Elgueta S,Leticia
Gormaz B,Juan Pablo
Ibáñez B,Carlos
Cuadra C,Cristián
author_facet Cotera F,Alejandro
Alvo A,Miriam
Sanhueza V,María Eugenia
Elgueta S,Leticia
Gormaz B,Juan Pablo
Ibáñez B,Carlos
Cuadra C,Cristián
author_sort Cotera F,Alejandro
title Efecto de la midodrina en la hipotensión sintomática en hemodiálisis
title_short Efecto de la midodrina en la hipotensión sintomática en hemodiálisis
title_full Efecto de la midodrina en la hipotensión sintomática en hemodiálisis
title_fullStr Efecto de la midodrina en la hipotensión sintomática en hemodiálisis
title_full_unstemmed Efecto de la midodrina en la hipotensión sintomática en hemodiálisis
title_sort efecto de la midodrina en la hipotensión sintomática en hemodiálisis
publisher Sociedad Médica de Santiago
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002000900007
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