Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico

We report a preterm infant with 30 weeks of gestation, that received broad spectrum antimicrobials during the first days of life. At nine days of life, the infant appeared with abdominal distension and hematochezia. A systolic murmur with changing auscultatory features also appeared. An echocardiogr...

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Autores principales:	Ruiz-Esquide E,Fernando, Díaz J,María Cristina, Wu H,Elba, Silva V,Víctor
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2002
Materias:	Amphotericin B Endocarditis, bacterial Infant, newborn, diseases Saccharomyces cerevisiae
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002001000012
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spelling	oai:scielo:S0034-988720020010000122014-08-21Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínicoRuiz-Esquide E,FernandoDíaz J,María CristinaWu H,ElbaSilva V,Víctor Amphotericin B Endocarditis, bacterial Infant, newborn, diseases Saccharomyces cerevisiae We report a preterm infant with 30 weeks of gestation, that received broad spectrum antimicrobials during the first days of life. At nine days of life, the infant appeared with abdominal distension and hematochezia. A systolic murmur with changing auscultatory features also appeared. An echocardiography showed an atrial vegetation. A yeast, that was identified as the emergent pathogen Saccharomyces cerevisiae appeared in two blood cultures. Treatment with amphotericin B was started, the dose was adjusted calculating the minimal inhibitory concentration of amphotericin B, and measuring plasma levels of the antimicrobial. Therefore the minimal effective dose was prescribed, avoiding its deleterious effects. After 14 days of antifungal therapy, a new echocardiography showed a reduction in the size of the atrial vegetation. At 35 days, it disappeared and amphotericin B was discontinued. On the outpatient follow up, the infant has shown a normal growth and a normal cardiac auscultation (Rev Méd Chile 2002; 130: 1165-9)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.10 20022002-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002001000012es10.4067/S0034-98872002001000012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Amphotericin B Endocarditis, bacterial Infant, newborn, diseases Saccharomyces cerevisiae
spellingShingle	Amphotericin B Endocarditis, bacterial Infant, newborn, diseases Saccharomyces cerevisiae Ruiz-Esquide E,Fernando Díaz J,María Cristina Wu H,Elba Silva V,Víctor Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico
description	We report a preterm infant with 30 weeks of gestation, that received broad spectrum antimicrobials during the first days of life. At nine days of life, the infant appeared with abdominal distension and hematochezia. A systolic murmur with changing auscultatory features also appeared. An echocardiography showed an atrial vegetation. A yeast, that was identified as the emergent pathogen Saccharomyces cerevisiae appeared in two blood cultures. Treatment with amphotericin B was started, the dose was adjusted calculating the minimal inhibitory concentration of amphotericin B, and measuring plasma levels of the antimicrobial. Therefore the minimal effective dose was prescribed, avoiding its deleterious effects. After 14 days of antifungal therapy, a new echocardiography showed a reduction in the size of the atrial vegetation. At 35 days, it disappeared and amphotericin B was discontinued. On the outpatient follow up, the infant has shown a normal growth and a normal cardiac auscultation (Rev Méd Chile 2002; 130: 1165-9)
author	Ruiz-Esquide E,Fernando Díaz J,María Cristina Wu H,Elba Silva V,Víctor
author_facet	Ruiz-Esquide E,Fernando Díaz J,María Cristina Wu H,Elba Silva V,Víctor
author_sort	Ruiz-Esquide E,Fernando
title	Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico
title_short	Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico
title_full	Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico
title_fullStr	Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico
title_full_unstemmed	Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico
title_sort	endocarditis verrucosa secundaria a saccharomyces cerevisiae: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2002
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002001000012
work_keys_str_mv	AT ruizesquideefernando endocarditisverrucosasecundariaasaccharomycescerevisiaecasoclinico AT diazjmariacristina endocarditisverrucosasecundariaasaccharomycescerevisiaecasoclinico AT wuhelba endocarditisverrucosasecundariaasaccharomycescerevisiaecasoclinico AT silvavvictor endocarditisverrucosasecundariaasaccharomycescerevisiaecasoclinico
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Endocarditis verrucosa secundaria a Saccharomyces cerevisiae: Caso clínico

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