Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano

Background: Small intestinal bacterial overgrowth generates endogenous ethanol production both in experimental animals and humans. Patients with cirrhosis have small intestinal bacterial overgrowth, but endogenous ethanol production has not been studied in them. Aim: To investigate endogenou ethanol...

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Autores principales:	Madrid S,Ana María, Hurtado H,Carmen, Gatica I,Sara, Chacón B,Inelia, Toyos D,Ana, Defilippi C,Carlos
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2002
Materias:	Breath tests Ethanol Lactulose Liver cirrhosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002001200001
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spelling	oai:scielo:S0034-988720020012000012003-02-05Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacterianoMadrid S,Ana MaríaHurtado H,CarmenGatica I,SaraChacón B,IneliaToyos D,AnaDefilippi C,Carlos Breath tests Ethanol Lactulose Liver cirrhosis Background: Small intestinal bacterial overgrowth generates endogenous ethanol production both in experimental animals and humans. Patients with cirrhosis have small intestinal bacterial overgrowth, but endogenous ethanol production has not been studied in them. Aim: To investigate endogenou ethanol production in patients with cirrhosis, altered intestinal motility and small intestinal bacterial overgrowth. Patients and methods: Eight patients with cirrhosis of different etiologies and altered gastrointestinal motility, consisting in changes in the migrating motor complex, were studied. All had also small intestinal bacterial overgrowth, measured by means of the H2 breath test with lactulose. Plasma ethanol levels were measured by gas liquid chromatography in fasting conditions and 120 min after a carbohydrate rich meal. Results: In fasting conditions, no patient had endogenous ethanol production. Alter the meal, ethanol in concentrations of 11.3 and 8.2 mg/del were detected in two patients. Negligible amounts of ethanol were detected in 4 patients and two patients had undetectable alcohol levels. Conclusions: A low endogenous production of ethanol was demonstrated in six of eight patients with cirrhosis (Rev Méd Chile 2002; 130: 1329-34)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.130 n.12 20022002-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002001200001es10.4067/S0034-98872002001200001
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Breath tests Ethanol Lactulose Liver cirrhosis
spellingShingle	Breath tests Ethanol Lactulose Liver cirrhosis Madrid S,Ana María Hurtado H,Carmen Gatica I,Sara Chacón B,Inelia Toyos D,Ana Defilippi C,Carlos Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano
description	Background: Small intestinal bacterial overgrowth generates endogenous ethanol production both in experimental animals and humans. Patients with cirrhosis have small intestinal bacterial overgrowth, but endogenous ethanol production has not been studied in them. Aim: To investigate endogenou ethanol production in patients with cirrhosis, altered intestinal motility and small intestinal bacterial overgrowth. Patients and methods: Eight patients with cirrhosis of different etiologies and altered gastrointestinal motility, consisting in changes in the migrating motor complex, were studied. All had also small intestinal bacterial overgrowth, measured by means of the H2 breath test with lactulose. Plasma ethanol levels were measured by gas liquid chromatography in fasting conditions and 120 min after a carbohydrate rich meal. Results: In fasting conditions, no patient had endogenous ethanol production. Alter the meal, ethanol in concentrations of 11.3 and 8.2 mg/del were detected in two patients. Negligible amounts of ethanol were detected in 4 patients and two patients had undetectable alcohol levels. Conclusions: A low endogenous production of ethanol was demonstrated in six of eight patients with cirrhosis (Rev Méd Chile 2002; 130: 1329-34)
author	Madrid S,Ana María Hurtado H,Carmen Gatica I,Sara Chacón B,Inelia Toyos D,Ana Defilippi C,Carlos
author_facet	Madrid S,Ana María Hurtado H,Carmen Gatica I,Sara Chacón B,Inelia Toyos D,Ana Defilippi C,Carlos
author_sort	Madrid S,Ana María
title	Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano
title_short	Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano
title_full	Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano
title_fullStr	Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano
title_full_unstemmed	Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano
title_sort	producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano
publisher	Sociedad Médica de Santiago
publishDate	2002
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872002001200001
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Producción endógena de alcohol en pacientes con cirrosis hepática, alteración motora y sobrecrecimiento bacteriano

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