Hipersensibilidad visceral: Un concepto a nuestro alcance

Despite significant advances in the recognition of etiological factors and pathological mechanisms, the pathophysiology of functional gastrointestinal disorders (FGD) is still not fully understood. Visceral hypersensitivity has been recognized as a characteristic of patients with FGD, especially in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Quera P,Rodrigo, Valenzuela E,Jorge
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2003
Materias:	Colonic diseases, functional Serotonin uptake inhibitors Visceral afferents
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000100014
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872003000100014
record_format	dspace
spelling	oai:scielo:S0034-988720030001000142003-05-13Hipersensibilidad visceral: Un concepto a nuestro alcanceQuera P,RodrigoValenzuela E,Jorge Colonic diseases, functional Serotonin uptake inhibitors Visceral afferents Despite significant advances in the recognition of etiological factors and pathological mechanisms, the pathophysiology of functional gastrointestinal disorders (FGD) is still not fully understood. Visceral hypersensitivity has been recognized as a characteristic of patients with FGD, especially in patients with irritable bowel syndrome (IBS). Visceral afferent input is modulated by a variety of mechanisms, operating between the gastrointestinal tract and the brain. Dysfunction of these regulatory mechanisms could distort gastrointestinal perceptions. Recent findings suggest that in the majority of cases of IBS the primary abnormality may be at the periphery with alterations of the motor and secretory sensory activity. Although imaging techniques indicate that there are also differences in cortical activation. Furthermore, selective serotonin reuptake inhibitors may benefit FGD. Recent pharmacological studies suggest that 5-HT3 antagonist such as alosetron and cilansetron, and 5-HT4 agonist such as tegaserod and prucalopride may also have a potential use in FGD (Rev Méd Chile 2003; 131: 85-92)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.1 20032003-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000100014es10.4067/S0034-98872003000100014
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Colonic diseases, functional Serotonin uptake inhibitors Visceral afferents
spellingShingle	Colonic diseases, functional Serotonin uptake inhibitors Visceral afferents Quera P,Rodrigo Valenzuela E,Jorge Hipersensibilidad visceral: Un concepto a nuestro alcance
description	Despite significant advances in the recognition of etiological factors and pathological mechanisms, the pathophysiology of functional gastrointestinal disorders (FGD) is still not fully understood. Visceral hypersensitivity has been recognized as a characteristic of patients with FGD, especially in patients with irritable bowel syndrome (IBS). Visceral afferent input is modulated by a variety of mechanisms, operating between the gastrointestinal tract and the brain. Dysfunction of these regulatory mechanisms could distort gastrointestinal perceptions. Recent findings suggest that in the majority of cases of IBS the primary abnormality may be at the periphery with alterations of the motor and secretory sensory activity. Although imaging techniques indicate that there are also differences in cortical activation. Furthermore, selective serotonin reuptake inhibitors may benefit FGD. Recent pharmacological studies suggest that 5-HT3 antagonist such as alosetron and cilansetron, and 5-HT4 agonist such as tegaserod and prucalopride may also have a potential use in FGD (Rev Méd Chile 2003; 131: 85-92)
author	Quera P,Rodrigo Valenzuela E,Jorge
author_facet	Quera P,Rodrigo Valenzuela E,Jorge
author_sort	Quera P,Rodrigo
title	Hipersensibilidad visceral: Un concepto a nuestro alcance
title_short	Hipersensibilidad visceral: Un concepto a nuestro alcance
title_full	Hipersensibilidad visceral: Un concepto a nuestro alcance
title_fullStr	Hipersensibilidad visceral: Un concepto a nuestro alcance
title_full_unstemmed	Hipersensibilidad visceral: Un concepto a nuestro alcance
title_sort	hipersensibilidad visceral: un concepto a nuestro alcance
publisher	Sociedad Médica de Santiago
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000100014
work_keys_str_mv	AT queraprodrigo hipersensibilidadvisceralunconceptoanuestroalcance AT valenzuelaejorge hipersensibilidadvisceralunconceptoanuestroalcance
_version_	1718436076606980096

Hipersensibilidad visceral: Un concepto a nuestro alcance

Ejemplares similares