Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central

The beginning of puberty is marked by breast growth in girls and testicular enlargement in boys. These occur at the age of 10.5 ± 2.0 years in females and 11.5 ± 2.0 years in males. Recent but controversial publications suggest that these events are being observed at younger ages, at least in the US...

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Autores principales:	García B,Hernán, Youlton R,Ronald, Burrows A,Raquel, Catanni O,Andreína
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2003
Materias:	Gonadorelin Hypothalamo-Hypophyseal System Puberty Puberty Preococious
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000100016
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spelling	oai:scielo:S0034-988720030001000162003-05-13Consenso sobre el diagnóstico y tratamiento de la pubertad precoz centralGarcía B,HernánYoulton R,RonaldBurrows A,RaquelCatanni O,Andreína Gonadorelin Hypothalamo-Hypophyseal System Puberty Puberty Preococious The beginning of puberty is marked by breast growth in girls and testicular enlargement in boys. These occur at the age of 10.5 ± 2.0 years in females and 11.5 ± 2.0 years in males. Recent but controversial publications suggest that these events are being observed at younger ages, at least in the USA. There are no studies demonstrating that this is true in Chile. For this reason we still consider that puberty is precocious when it occurs before 8.0 years in girls and before 9.0 years in boys. True or central precocious puberty (CPP) must be distinguished from peripheral or pseudoprecocious puberty (PPP), from premature telarche and from premature adrenarche. We suggest that the workup of a patient with premature development should include an LHRH test to demonstrate if the hypothalamic-pituitary axis is activated, plasma levels of sex steroids, bone age and pelvic ultrasound in girls. All children with CPP should have a CAT scan or MNR of the brain, since a lesion of the central nervous system is observed in 15% of the girls and 50% of the boys whith CPP. Additional studies are needed in cases of PPP. The aim of treating CPP is to avoid adult short stature that results from premature fusion of the epiphysis and to avoid eventual emotional and psychological stress. Treatment consists of monthly intramuscular injections of a depot preparation of LHRH analogs. Suppression of pituitary and gonadal activity produces regression of secondary sex characteristics and slowing down of growth velocity and bone maturation. The opportunity, duration of treatment and their effect on final stature are discussed (Rev Méd Chile 2003; 131: 95-110)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.1 20032003-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000100016es10.4067/S0034-98872003000100016
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Gonadorelin Hypothalamo-Hypophyseal System Puberty Puberty Preococious
spellingShingle	Gonadorelin Hypothalamo-Hypophyseal System Puberty Puberty Preococious García B,Hernán Youlton R,Ronald Burrows A,Raquel Catanni O,Andreína Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central
description	The beginning of puberty is marked by breast growth in girls and testicular enlargement in boys. These occur at the age of 10.5 ± 2.0 years in females and 11.5 ± 2.0 years in males. Recent but controversial publications suggest that these events are being observed at younger ages, at least in the USA. There are no studies demonstrating that this is true in Chile. For this reason we still consider that puberty is precocious when it occurs before 8.0 years in girls and before 9.0 years in boys. True or central precocious puberty (CPP) must be distinguished from peripheral or pseudoprecocious puberty (PPP), from premature telarche and from premature adrenarche. We suggest that the workup of a patient with premature development should include an LHRH test to demonstrate if the hypothalamic-pituitary axis is activated, plasma levels of sex steroids, bone age and pelvic ultrasound in girls. All children with CPP should have a CAT scan or MNR of the brain, since a lesion of the central nervous system is observed in 15% of the girls and 50% of the boys whith CPP. Additional studies are needed in cases of PPP. The aim of treating CPP is to avoid adult short stature that results from premature fusion of the epiphysis and to avoid eventual emotional and psychological stress. Treatment consists of monthly intramuscular injections of a depot preparation of LHRH analogs. Suppression of pituitary and gonadal activity produces regression of secondary sex characteristics and slowing down of growth velocity and bone maturation. The opportunity, duration of treatment and their effect on final stature are discussed (Rev Méd Chile 2003; 131: 95-110)
author	García B,Hernán Youlton R,Ronald Burrows A,Raquel Catanni O,Andreína
author_facet	García B,Hernán Youlton R,Ronald Burrows A,Raquel Catanni O,Andreína
author_sort	García B,Hernán
title	Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central
title_short	Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central
title_full	Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central
title_fullStr	Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central
title_full_unstemmed	Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central
title_sort	consenso sobre el diagnóstico y tratamiento de la pubertad precoz central
publisher	Sociedad Médica de Santiago
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000100016
work_keys_str_mv	AT garciabhernan consensosobreeldiagnosticoytratamientodelapubertadprecozcentral AT youltonrronald consensosobreeldiagnosticoytratamientodelapubertadprecozcentral AT burrowsaraquel consensosobreeldiagnosticoytratamientodelapubertadprecozcentral AT catannioandreina consensosobreeldiagnosticoytratamientodelapubertadprecozcentral
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Consenso sobre el diagnóstico y tratamiento de la pubertad precoz central

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